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1. Content Type:Study Protocol

     |  8 February 2019

   VIA Family—a family-based early intervention versus treatment as usual for familial high-risk children: a study protocol for a randomized clinical trial

   Authors:Anne D. Müller, Ida C. T. Gjøde, Mette S. Eigil, Helle Busck, Merete Bonne, Merete Nordentoft and Anne A. E. Thorup
2. Content Type:Research

     |  8 February 2019

   Stroke aetiological classification reliability and effect on trial sample size: systematic review, meta-analysis and statistical modelling

   Authors:Azmil H. Abdul-Rahim, David Alexander Dickie, Johann R. Selvarajah, Kennedy R. Lees and Terence J. Quinn
3. Content Type:Study Protocol

     |  8 February 2019

   Physical Activity In Renal Disease (PAIRED) and the effect on hypertension: study protocol for a randomized controlled trial

   Authors:Stephanie Thompson, Natasha Wiebe, Gabor Gyenes, Rachelle Davies, Jeyasundar Radhakrishnan and Michelle Graham
4. Content Type:Methodology

     |  8 February 2019

   Design and implementation of a large and complex trial in emergency medical services

   Authors:Maria J. Robinson, Jodi Taylor, Stephen J. Brett, Jerry P. Nolan, Matthew Thomas, Barnaby C. Reeves, Chris A. Rogers, Sarah Voss, Madeleine Clout and Jonathan R. Benger
5. Content Type:Research

     |  8 February 2019

   How context can impact clinical trials: a multi-country qualitative case study comparison of diagnostic biomarker test interventions

   Authors:Marco J. Haenssgen, Nutcha Charoenboon, Nga T. T. Do, Thomas Althaus, Yuzana Khine Zaw, Heiman F. L. Wertheim and Yoel Lubell

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