ACTUALIZACIÓN MÉDICO-CONTINUADA EN AUTISMO ► Genomics|Features|Autism [idioma inglés únicamente]

Genomics|Features|Autism

Autism

Autism: Genomic Insights - September 1, 2015

CDC and Related Info

• CDC autism information: Why act early?
• The association between assisted reproductive technology and autism spectrum disorder
• New CDC funding will expand knowledge about children with autism spectrum disorder
• CDC information on autism spectrum disorders
• Living with Autism
• Autism and Developmental Disabilities Monitoring (ADDM) Network
• Study to Explore Early Development (SEED)
• CDC key findings:Using standardized diagnostic instruments to classify children with autism to help find causes of the disorder
• CDC is funding the largest multistate collaborative study in the United States to help identify factors that may put children at risk for autism spectrum disorders
• Genes reported in relation to autism, including genomewide association studies via theHuGE Navigator

Complex autism spectrum disorders and cutting-edge molecular diagnostic tests
Miles JH, JAMA, September 1, 2015

Molecular diagnostic yield of chromosomal microarray analysis and whole-exome sequencing in children with autism spectrum disorder
Tammimies K et al. JAMA, September 1, 2015

Decoding autism, by H Millar et al, Genome Magazine, July 2015

Genetic testing for developmental disabilities, intellectual disability, and autism spectrum disorder
Rockville (MD):Agency for Healthcare Research and Quality (US) 2015 Jun

Monogenic and chromosomal causes of isolated speech and language impairment.
Barnett CP et al. J. Med. Genet. 2015 Jul 2.

Genetics of autism spectrum disorder: an update on copy number variations leading to autism in the next generation sequencing era.
Alsagob M et al. Discov Med 2015 May (106) 367-79

Discovery of rare mutations in autism: Elucidating neurodevelopmental mechanisms.
Gamsiz ED et al. Neurotherapeutics 2015 Jul (3) 553-71

The role of epigenetic change in autism spectrum disorders.
Loke YJ et al. Front Neurol 2015 107

Autism Awareness Month - May 18, 2015

Excess of rare, inherited truncating mutations in autism.
Krumm N et al. Nat. Genet. 2015 May 11.

Promising forecast for autism spectrum disorders.
King B H et al. JAMA 2015 Apr 21. (15) 1518-9

CDC autism information: Why act early?

CDC information on Autism Awareness Month  [PDF 532.33 KB]

CDC Key Findings: The association between assisted reproductive technology and autism spectrum disorder

Heritability of autism spectrum disorder in a UK population-based twin sample.
Colvert E et al. JAMA Psychiatry 2015 Mar 4.

The promise of multi-omics and clinical data integration to identify and target personalized healthcare approaches in autism spectrum disorders.
Higdon R et al. OMICS 2015 Apr (4) 197-208

Autism spectrum disorder (ASD) and Fragile X syndrome (FXS): Two overlapping disorders reviewed through electroencephalography-what can be interpreted from the available information?
Devitt NM et al. Brain Sci 2015 (2) 92-117

Inhibition-based biomarkers for autism spectrum disorder.
Levin AR et al. Neurotherapeutics 2015 Mar 27.

Loss of δ-catenin function in severe autism.
Turner TN et al. Nature 2015 Mar 25.

High-resolution chromosome ideogram representation of currently recognized genes for autism spectrum disorders.
Butler MG et al. Int J Mol Sci 2015 (3) 6464-95

Update on autism spectrum disorder: Vaccines, genomes, and social skills training.
McGuinness TM et al. J Psychosoc Nurs Ment Health Serv 2015 Mar 18. 1-4

Common polygenic risk for autism spectrum disorder (ASD) is associated with cognitive ability in the general population.
Clarke TK et al. Mol. Psychiatry 2015 Mar 10.

Genetic factors are "substantial" in aetiology of autism, study of UK twins finds.
Wise J et al. BMJ 2015 h1212

Prediction of Autism by Translation and Immune/Inflammation Coexpressed Genes in Toddlers From Pediatric Community Practices.
Pramparo T et al. JAMA Psychiatry 2015 Apr 1. (4) 386-394

Genetic investigation of autism-related social communication deficits.
Campbell DB et al. Am J Psychiatry 2015 Mar 1. (3) 212-3

Autism: New CDC Funding and Recent Genomic Studies - February 3, 2015

New CDC funding will expand knowledge about children with autism spectrum disorder

Predictors of later outcomes in younger siblings of children with autism spectrum disorder, by William Riley, NIH OBSSR Jan 21

18-month predictors of later outcomes in younger siblings of children with autism spectrum disorder: a baby siblings research consortium study.
Chawarska Katarzyna et al. Journal of the American Academy of Child and Adolescent Psychiatry2014 Dec (12) 1317-1327.e1

Whole-genome sequencing of quartet families with autism spectrum disorder. 
Ryan K C Yuen, et al. Nature Medicine, January 26, 2015

Largest-ever autism genome study finds most siblings have different autism-risk genes, Medical Xpress, Jan 26

From de novo mutations to personalized therapeutic interventions in autism.
Brandler WM, Sebat J. Annu Rev Med. 2015 Jan 14;66:487-507.

Integrated systems analysis reveals a molecular network underlying autism spectrum disorders.
Li J, et al. Mol Syst Biol. 2014 Dec 30;10(12):774

The phenotypic manifestations of rare genic CNVs in autism spectrum disorder.
Merikangas AK, et al. Mol Psychiatry. 2014 Nov 25

Where are the strongest associations between autistic traits and traits of ADHD? evidence from a community-based twin study.
Taylor MJ, et al. Eur Child Adolesc Psychiatry. 2015 Jan 20.

Autism: Recent Genomic Insights - November 6, 2014

Scientists implicate more than 100 genes in causing autism, by Nancy Shute, NPR, October 29, 2014 

The contribution of de novo coding mutations to autism spectrum disorder. 
Ivan Iossifov et al. Nature, October 29, 2014

Anarchic autism genetics gain a touch of clarity, by Gary Stix, Scientific American, Oct 30

Synaptic, transcriptional and chromatin genes disrupted in autism 
Silvia De Rubeis, et al Nature, October 29, 2014

CDC information on autism spectrum disorders

CDC key findings: Using standardized diagnostic instruments to classify children with autism to help find causes of the disorder

Gene trawls haul in new finds on autism, MS, NBS News, Oct 29

Autism: Genetic and Environmental Contributions - July 31, 2014

CDC Expert Commentary Medscape Podcast:  Autism spectrum disorders: Learn the signs. Act early. Georgina Peacock, July 21, 2014

Most genetic risk for autism resides with common variation. 
Trent Gaugler et al. Nature Genetics, July 20, 2014

Autism spectrum disorder. Swimming in autism mutations
Anne Schaefer. Science Translational Medicine, July 23, 2014

NIH news release: Common gene variants account for most genetic risk for autism-Roles of heritability, mutations, environment estimated

Common genes implicated in autism study, by Robert Preidt, HealthDay, Jul 20

CDC information on autism spectrum disorders

CDC is funding the largest multistate collaborative study in the United States to help identify factors that may put children at risk for autism spectrum disorders

Editorial: The genetic and environmental contributions to autism: Looking beyond twins
Diana E. Schendel, et al. JAMA, May 7, 2014

Did you know? >450 genes have been reported in relation to risk and outcomes of Autism including 13 genomewide association studies. To find out more, visit the HuGE Navigator 

Check out genetic disorders and tests associated with autism using the NIH Genetic Testing Registry