miércoles, 15 de mayo de 2019

Cystic Fibrosis News Today Weekly Digest


Cystic Fibrosis Weekly Update

Contents:

Early, Rapid BMI Increase May Affect Overall Growth of CF Children, Study Suggests

May 15, 2019 07:00 am | Alice Melão



BMI and growthRapid weight gain early in life may have a long-term negative impact on the growth of children with cystic fibrosis (CF), a study has found. This finding suggests that nutritional interventions aimed at supporting the child’s normal growth should be implemented early on, taking into consideration their weight and overall body mass index. The study, […]
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In Cystic Fibrosis Awareness Month, I Look Back to Anticipate the Future

May 14, 2019 09:00 am | Brad Dell



What CF Feels Like, cystic fibrosis awareness monthThe night I received my first Hill-Rom Vest — at age 5 — was a fun one. It was a beast of a machine in the mid-1990s, a white box weighing maybe 50 pounds. Large, plastic, hollow coils connected the machine to a bulky, black vest, which fitted around my torso and shoulders. The goal […]
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Phages, Viruses that Attack Bacteria, Are a Potential Therapy Against Infections, Case Report Suggests

May 14, 2019 07:30 am | Alejandra Viviescas



phages potential therapyThe case report of a cystic fibrosis (CF) patient suggests that phages — viruses that naturally infect and kill bacteria — are a potential personalized therapy against infections caused by antibiotic-resistant bacteria. The study, “Engineered bacteriophages for treatment of a patient with a disseminated drug-resistant Mycobacterium abscessus,” was published in the journal Nature Medicine. Patients […]
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Trial of Nebulized CF Candidate Therapy Completes Single-ascending Dosing

May 13, 2019 09:30 am | Patricia Inacio, PhD



MRT5005The RESTORE-CF clinical trial investigating Translate Bio’s candidate therapy MRT5005 has completed the single-ascending dose regimen in patients with cystic fibrosis (CF), the company announced. The ongoing Phase 1/2 trial (NCT03375047) is testing the safety and efficacy of single and multiple escalating doses of nebulized MRT5005, compared with each other and a placebo, in 32 adults with CF who have class […]
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