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George Shuklin [CC BY-SA 1.0 (https://creativecommons.org/licenses/by-sa/1.0)]

Featured Article: Mouse germ line mutations due to retrotransposon insertions

In this review article, the authors explore the role of tranposable elements insertions in germ line mutations in mice as well as the similarities and differences between mice and humans with respect to TE-induced mutations.

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1. Content Type:Research

     |  3 May 2019

   Characterization of a relaxase belonging to the MOBTfamily, a widespread family in Firmicutes mediating the transfer of ICEs

   Authors:Nicolas Soler, Emilie Robert, Isaure Chauvot de Beauchêne, Philippe Monteiro, Virginie Libante, Bernard Maigret, Johan Staub, David W. Ritchie, Gérard Guédon, Sophie Payot, Marie-Dominique Devignes and Nathalie Leblond-Bourget
2. Content Type:Research

     |  3 May 2019

   Insertion of a chimeric retrotransposon sequence in mouse Axin1 locus causes metastable kinky tail phenotype

   Authors:Zhuqing Wang, Hayden McSwiggin, Simon J. Newkirk, Yue Wang, Daniel Oliver, Chong Tang, Sandy Lee, Shawn Wang, Shuiqiao Yuan, Huili Zheng, Ping Ye, Wenfeng An and Wei Yan
3. Content Type:Research

     |  27 April 2019

   Human transposons are an abundant supply of transcription factor binding sites and promoter activities in breast cancer cell lines

   Authors:Jiayue-Clara Jiang and Kyle R. Upton
4. Content Type:Review

     |  13 April 2019

   Mouse germ line mutations due to retrotransposon insertions

   Authors:Liane Gagnier, Victoria P. Belancio and Dixie L. Mager
5. Content Type:Research

     |  8 April 2019

   Subtype classification and functional annotation of L1Md retrotransposon promoters

   Authors:Meng Zhou and Andrew D. Smith