Cystic Fibrosis News Today Daily Digest

Cystic Fibrosis Weekly Update Contents: Phase 1b Study of CB-280 for CF Chronic Lung Infections May Open by September How to Be Forgotten in 800 Words or Less Stuck Between Nostalgia and Reality Rare Diseases Clinical Research Network Opens Online Survey on COVID-19 Gene Therapy, KB407, Seen to Restore CFTR Protein in Cell Studies Phase 1b Study of CB-280 for CF Chronic Lung Infections May Open by September May 13, 2020 07:00 am | Joana Carvalho, PhD Calithera Biosciences announced plans to open by September a first clinical study of its oral investigational therapy CB-280 in people with cystic fibrosis (CF). The Phase 1b, dose-escalating trial (NCT04279769) in up to 32 adults with cystic fibrosis and chronic lung infections caused by Pseudomonas aeruginosa was expected to begin enrolling in April, but its launch was pushed […] The post Phase 1b Study of CB-280 for CF Chronic Lung Infections May Open by September appeared first on Cystic Fibrosis News Today. Read More How to Be Forgotten in 800 Words or Less May 12, 2020 03:00 pm | Bailey Vincent By the time you finish reading this, you’ll have forgotten me. I worry about being forgotten more than I should. I’ve lost countless friends whom I remember at odd times and think, “Wow, I haven’t thought about them for so long.” I remember random celebrities like Jennifer Garner and say, “Why hasn’t Instagram shown her […] The post How to Be Forgotten in 800 Words or Less appeared first on Cystic Fibrosis News Today. Read More Stuck Between Nostalgia and Reality May 12, 2020 09:00 am | Brad Dell “I love the smell of napalm in the morning,” said Lt. Col. Bill Kilgore. He proceeded to describe bombing a hill, and how the resulting carnage “smelled like victory.” He then frowned and said sadly, “Someday this war’s gonna end.” Kilgore serves as the war addict archetype for the film “Apocalypse Now.” My dad has […] The post Stuck Between Nostalgia and Reality appeared first on Cystic Fibrosis News Today. Read More Rare Diseases Clinical Research Network Opens Online Survey on COVID-19 May 12, 2020 07:00 am | Mary Chapman The Rare Diseases Clinical Research Network (RDCRN) has opened an online survey to better understand how the COVID-19 outbreak is affecting people with rare diseases, their families, and caregivers. Survey questions cover a patient’s physical and mental health, supply of treatments, and access to healthcare, among other disease-related issues and those brought by the pandemic. […] The post Rare Diseases Clinical Research Network Opens Online Survey on COVID-19 appeared first on Cystic Fibrosis News Today. Read More Gene Therapy, KB407, Seen to Restore CFTR Protein in Cell Studies May 12, 2020 07:00 am | Marisa Wexler MS A potential gene therapy for cystic fibrosis, KB407, is able to induce the expression of normal CFTR protein in cell models of CF, its developer, Krystal Biotech, reports. These data are in the poster, “In vitro Pharmacology of KB407, an HSV-1 based gene therapy vector, for the treatment of cystic fibrosis” (abstract 282, page 131), […] The post Gene Therapy, KB407, Seen to Restore CFTR Protein in Cell Studies appeared first on Cystic Fibrosis News Today. Read More   Recent News Researchers Develop Promising Antibiotic Molecule for Drug-resistant Lung Infections Trikafta Very Effective CF Therapy, But Still Too Costly, ICER Reports CF Foundation, Beam Partner to Offer Free Online Exercise Classes AzurRx BioPharma Will Conduct Phase 2b Trial of MS1819 at TDN Clinical Sites Stop Making Yourself Sick About Other Sick People