HMGB1 protein may play a key role in pulmonary inflammation, tissue damage in severe COVID-19 cases

HMGB1 protein may play a key role in pulmonary inflammation, tissue damage in severe COVID-19 cases

HMGB1 protein may play a key role in pulmonary inflammation, tissue damage in severe COVID-19 cases

In severe cases of COVID-19, a massive release of the endogenous protein HMGB1 in the lungs may contribute to pulmonary inflammation and tissue damage, according to a review article published today in the scientific journal Molecular Medicine.