Loss of homeostatic microglial phenotype in CSF1R- related Leukoencephalopathy | Acta Neuropathologica Communications | Full Text

Loss of homeostatic microglial phenotype in CSF1R- related Leukoencephalopathy | Acta Neuropathologica Communications | Full Text

Loss of homeostatic microglial phenotype in CSF1R-related Leukoencephalopathy

Microglia are resident macrophages of the central nervous system, and their unique molecular signature is dependent upon CSF-1 signaling. Previous studies have demonstrated the importance of CSF-1R in survival...

Authors:Liam Kempthorne, Hyejin Yoon, Charlotte Madore, Scott Smith, Zbigniew K. Wszolek, Rosa Rademakers, Jungsu Kim, Oleg Butovsky and Dennis W. Dickson

Citation:Acta Neuropathologica Communications 2020 8:72

Content type:Research

Published on: 19 May 2020

• ViewFull Text
 
• ViewPDF