The contribution of large genomic rearrangements in BRCA1 and BRCA2 to South African familial breast cancer | BMC Cancer | Full Text

The contribution of large genomic rearrangements in BRCA1 and BRCA2 to South African familial breast cancer | BMC Cancer | Full Text

The contribution of large genomic rearrangements in BRCA1 and BRCA2 to South African familial breast cancer

Pathogenic variants that occur in the familial breast cancer genes (BRCA1/2) lead to truncated ineffective proteins in the majority of cases. These variants are mostly represented by small deletions/insertions, n...

Authors:Nerina C. van der Merwe, Jaco Oosthuizen, Magdalena Theron, George Chong and William D. Foulkes

Citation:BMC Cancer 2020 20:391

Content type:Research article

Published on: 6 May 2020

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