Priya Mistry
Priya is a Journal Development Editor at BMC and works within the Medicine and Life Science portfolio. She graduated from the University of Warwick with a degree in Biomedical Sciences.
Can maternal exposure to carbon black nanoparticles affect male fertility?
Carbon black nanoparticles are manufactured for use in rubber products, as a color pigment in plastics, paint and ink and used to model exposure to air pollution particles. These particles have been shown to have toxic effects andprevious mice studies have shown that maternal exposure can affect the sperm count in male offspring. In this Q&A, Dr Karin Sørig Hougaard and PhD student Astrid Skovmand discuss their recently published paper in Particle and Fibre Toxicology which shows that in contrast to previous studies, maternal exposure to carbon black nanoparticles does not affect future (fourth) generations of male mice sperm counts.
Car Exhaust (via flickr/Simone Ramella)
What made you want to research this issue?
Our group has conducted research on fetal programming by maternal occupational exposures for more than two decades, in order to study whether these may pose a risk for women working during pregnancy. The fetal programming hypothesis proposes that environmental factors may affect fetal development so as to prepare the child for the conditions awaiting in life after birth. Since 2006, a large part of our research has focused on the potential for fetal programming by inhaled nanosized particles.
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