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Genomics|Features|Abdominal Aortic Aneurysm

Abdominal Aortic Aneurysm

Abdominal Aortic Aneurysm: Public Health and Genomic Insights - March 18, 2015

Screening for abdominal aortic aneurysm 
Bird AN et al. JAMA March 17, 2015

Abdominal aortic diameter is increased in males with a family history of abdominal aortic aneurysms: results from the Danish VIVA-trial.
Joergensen TMM et al. Eur J Vasc Endovasc Surg 2014 Dec (6) 669-75

Risk profiles for aortic dissection and ruptured or surgically treated aneurysms: a prospective cohort study.
Landenhed M et al. J Am Heart Assoc 2015 Jan (1) e001513

Biomechanics and gene expression in abdominal aortic aneurysm.
Reeps C et al. J. Vasc. Surg. 2014 Dec (6) 1640-7.e1-2

Genomic insights into abdominal aortic aneurysms.
Bown MJ et al. Ann R Coll Surg Engl 2014 Sep (6) 405-14

2014 ESC Guidelines on the diagnosis and treatment of aortic diseases: Document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. The Task Force for the Diagnosis and Treatment of Aortic Diseases of the European Society of Cardiology (ESC).
Erbel R et al. Eur. Heart J. 2014 Nov 1. (41) 2873-926

The alpha-2-antiplasmin Arg407Lys polymorphism is associated with Abdominal Aortic Aneurysm.
Bridge KI et al. Thromb. Res. 2014 Sep (3) 723-8

Anatomical similarity of abdominal aortic aneurysms in monozygotic twins.
Kitagawa A et al. Ann Vasc Dis 2014 (2) 187-90

ELN gene triplication responsible for familial supravalvular aortic aneurysm.
Guemann AS et al. Cardiol Young 2015 Apr (4) 712-7

Analysis of multiple genetic polymorphisms in aggressive-growing and slow-growing abdominal aortic aneurysms.
Duellman Tyler et al. J. Vasc. Surg. 2014 Sep (3) 613-21.e3

Abdominal Aortic Aneurysm: Screening, Family History and Genetics - September 4, 2014

CDC information: Aortic aneurysm fact sheet. Accounts for more than 10,000 deaths every year in the United States

Risk factors for abdominal aortic aneurysm include family history, from the Mayo Clinic 

The United States Preventive Services Task Force recommends one-time screening for abdominal aortic aneurysm (AAA) by ultrasonography in men ages 65 to 75 years who have ever smoked. Family history of abdominal aortic aneurysm requiring surgical repair can be used in informed decision making among nonsmokers (2014)

Did you know? > 100 genes have been reported in relation to risk and outcomes of abdominal aortic aneurysm including 6 genomewide association studies. To find out more, visit the HuGE Navigator

Epidemiology, risk factors, pathogenesis and natural history of abdominal aortic aneurysm, Emile Mohler, Up to Date, August 2014

Genetics of abdominal aortic aneurysm.
Golledge J, Kuivaniemi H. Curr Opin Cardiol. 2013 May;28(3):290-6.  

2014 ESC guidelines on the diagnosis and treatment of aortic diseases: Document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult 
Erbel R, et al. Eur Heart J 2014 Aug