Skin Cancer
Skin Cancer: Public Health and Genomic Insights - March 17, 2015
CDC information: Skin cancer prevention
Traveling for spring break? Don't forget to pack, protect yourself from the sun, and go!
Traveling for spring break? Don't forget to pack, protect yourself from the sun, and go!
Common genetic risk for melanoma encourages preventive behavior change.
Diseati Lori et al. J Pers Med 2015 (1) 36-49
Diseati Lori et al. J Pers Med 2015 (1) 36-49
Genetic variants in Hippo pathway genes YAP1, TEAD1 and TEAD4 are associated with melanoma-specific survival.
Yuan Hua et al. Int. J. Cancer 2015 Jan 13.
Yuan Hua et al. Int. J. Cancer 2015 Jan 13.
Cancer systems biology of TCGA SKCM: efficient detection of genomic drivers in melanoma.
Guan Jian et al. Sci Rep 2015 7857
Guan Jian et al. Sci Rep 2015 7857
Genetic basis for clinical response to CTLA-4 blockade in melanoma.
Snyder Alexandra et al. N. Engl. J. Med. 2014 Dec 4. (23) 2189-99
Snyder Alexandra et al. N. Engl. J. Med. 2014 Dec 4. (23) 2189-99
Milestones in skin carcinogenesis: the biology of multistage carcinogenesis.
Balmain Allan et al. J. Invest. Dermatol. 2014 (e1) E2-7
Balmain Allan et al. J. Invest. Dermatol. 2014 (e1) E2-7
Genetics of skin cancer (PDQ®), from the National Cancer Institute
from the National Cancer InstituteMelanoma Genomics: Sun Exposure and New Therapies - November 26, 2014
Risk factors for melanoma include genes and family history, from the National Cancer Institute
from the National Cancer Institute
A special supplement from Nature Outlook: Melanoma — the deadliest form of skin cancer — is on the rise in many parts of the world. But new treatments, and efforts to tell people how to prevent it, could mean we will soon gain the upper hand on the disease. November, 2014
is on the rise in many parts of the world. But new treatments, and efforts to tell people how to prevent it, could mean we will soon gain the upper hand on the disease. November, 2014
The cancer that rises with the Sun.
David Holmes Nature, 515, S110–S111, 20 November 2014
David Holmes Nature, 515, S110–S111, 20 November 2014
Risk factors: Riddle of the rays
Cassandra Willyard, Nature 515, S112–S113 (20 November 2014)
Cassandra Willyard, Nature 515, S112–S113 (20 November 2014)
Epidemiology, risk factors, prevention, and early detection of melanoma.
Azoury SC, Lange JR. Surg Clin North Am. 2014 Oct;94(5):945-62
Azoury SC, Lange JR. Surg Clin North Am. 2014 Oct;94(5):945-62
Did you know? 389 genes have been reported in relation to melanoma risk and outcomes, including 33 genomewide association studies. To find out more, check out the HuGE Navigator
Recent Genomic Insights
Interactions between ultraviolet light and MC1R and OCA2 variants are determinants of childhood nevus and freckle phenotypes.
Anna E. Barón et al. CEBP, November 18, 2014
Anna E. Barón et al. CEBP, November 18, 2014
Genes and sun behaviors during childhood may play large role in future melanoma risk, American Association for Cancer Research, November 19, 2014
American Association for Cancer Research, November 19, 2014
Editorial: Somatic mutations and immunotherapy outcome with CTLA-4 blockade in melanoma.
NEJM, November 19, 2014.
NEJM, November 19, 2014.
Genetic basis for clinical response to CTLA-4 blockade in melanoma.
NEJM, November 19, 2014
NEJM, November 19, 2014
Skin Cancer: Sun Exposure and Genetics - August 7, 2014
Genetics of skin cancer, from the National Cancer Institute
from the National Cancer Institute
Did you know? 286 genes have been reported in relation to risk and outcomes of skin cancer, including 17 genomewide association studies and 29 meta analyses. To find out more, visit the HuGE Navigator
and 29 meta analyses. To find out more, visit the HuGE Navigator
Learn about genetic disorders and tests associated with skin cancer from the NIH Genetic Testing Registry
from the NIH Genetic Testing Registry
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