Dear Prof CERASALE MORTEO,
BMC Medicine is pleased to bring you the first articles from our special thematic collection on landmark oncology trials.
This article collection includes carefully selected articles from invited experts on landmark trials that had the most substantial influence on the clinical practice or provided some critical evidence that enhanced our understanding in this field. It will also feature current topics in the trial design.
Cancer is a heterogeneous disease with no single treatment that is successful across all cancer types. Identification of specific genetic changes in some cancer types has been crucial in improving therapy outcomes, as it has allowed individualized targeted therapy, broadly called ‘precision medicine’. Together with the other characteristics of a tumour, like location, volume, or spread, genetic factors dictate feasible therapeutic options, which range from surgery, radiotherapy, chemotherapy, to novel targeted agents and immunotherapy. With treatment resistance being a wide-spread issue, the most promising solution seems to be the use of combination therapy with different drugs or even treatment modalities. Read more...
The BMC Medicine Team
*The Impact Factor (IF) is just one measure used for evaluating the impact of research. For further information on the IF and alternative metrics used to measure the impact of research, please click here.
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