Measles Clinical Features
For Healthcare Professionals
On this Page
- Clinical Features
- The Virus
- People at High Risk for Complications
- Diagnosis and Laboratory Testing
- Evidence of Immunity
- Post-exposure Prophylaxis
Advice for Travelers
- Travel Notice: Watch (Level 1):Measles in the Philippines
- One out of every 1,000 measles cases will develop acute encephalitis, which often results in permanent brain damage.
- One or two out of every 1,000 children who become infected with measles will die from respiratory and neurologic complications.
- Subacute sclerosing panencephalitis (SSPE) is a rare, but fatal degenerative disease of the central nervous system characterized by behavioral and intellectual deterioration and seizures that generally develop 7 to 10 years after measles infection.
- Infants and children aged <5 li="" years="">
- Adults aged >20 years
- Pregnant women
- People with compromised immune systems, such as from leukemia and HIV infection 5>
- written documentation of adequate vaccination:
- one or more doses of a measles-containing vaccine administered on or after the first birthday for preschool-age children and adults not at high risk
- two doses of measles-containing vaccine for school-age children and adults at high risk, including college students, healthcare personnel, and international travelers
- laboratory evidence of immunity
- laboratory confirmation of measles
- birth in the United States before 1957
Students at post-high school educational institutions
- Infants 6 through 11 months of age should receive one dose of MMR vaccine
- Children 12 months of age or older should have documentation of two doses of MMR vaccine (the first dose of MMR vaccine should be administered at age 12 months or older; the second dose no earlier than 28 days after the first dose)
- Teenagers and adults born during or after 1957 without evidence of immunity against measles should have documentation of two doses of MMR vaccine, with the second dose administered no earlier than 28 days after the first dose
- CDC. Prevention of Measles, Rubella, Congenital Rubella Syndrome, and Mumps, 2013: Summary Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR 2013;62(RR04);1-34.
MMR vaccine as post-exposure prophylaxis
Immunoglobulin (IG) as post-exposure prophylaxis
Post-exposure prophylaxis for healthcare personnel
- Siegel JD, Rhinehart E, Jackson M, Chiarello L, and the Healthcare Infection Control Practices Advisory Committee, 2007 Guidelines for Isolation Precautions: Preventing Transmission of Infectious Agents in Healthcare Settings.