BRCA MUTATIONS

https://phgkb.cdc.gov/GAPPKB/phgHome.do


Last Posted: Jun 10, 2017

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• Population screening for BRCA1/BRCA2 mutations: lessons from qualitative analysis of the screening experience.  
  Lieberman Sari et al. Genetics in medicine : official journal of the American College of Medical Genetics 2017 Jun (6) 628-634
• Combined immune checkpoint blockade as a therapeutic strategy for BRCA1-mutated breast cancer.  
  Nolan Emma et al. Science translational medicine 2017 Jun (393)
• Making Sense of Cancer Headlines  
  XRAYS, Facing Our Risk Empowered
• Distinct implications of different BRCA mutations: efficacy of cytotoxic chemotherapy, PARP inhibition and clinical outcome in ovarian cancer.  
  Hollis Robert L et al. OncoTargets and therapy 2017 102539-2551
• PARP inhibitors in ovarian cancer: evidence, experience and clinical potential.  
  Evans Tarra et al. Therapeutic advances in medical oncology 2017 Apr 9(4) 253-267
• Multi-institutional Evaluation of Women at High Risk of Developing Breast Cancer.  
  Hermel David J et al. Clinical breast cancer 2017 Apr
• Why Would Men Need Genetic Testing for Breast Cancer Too?  
  Cleveland Clinic Health Essentials
• Multigene panels in Ashkenazi Jewish patients yield high rates of actionable mutations in multiple non-BRCA cancer-associated genes.  
  Frey Melissa K et al. Gynecologic oncology 2017 May
• Practice Patterns of Hereditary Ovarian Cancer Management in Korea.  
  Choi Min Chul et al. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2017 May
• Quantifying family dissemination and identifying barriers to communication of risk information in Australian BRCA families.  
  Healey Emma et al. Genetics in medicine : official journal of the American College of Medical Genetics 2017 May
• Quantifying family dissemination and identifying barriers to communication of risk information in Australian BRCA families  
  E Healey et al, Genetics in Medicine, May 11, 2017
• "I Don't Want to Be an Ostrich": Managing Mothers' Uncertainty during BRCA1/2 Genetic Counseling.  
  Fisher Carla L et al. Journal of genetic counseling 2017 Jun 26(3) 455-468
• A Dedicated Follow-Up Clinic for BRCA Mutation Carriers.  
  Yerushalmi Rinat et al. The Israel Medical Association journal : IMAJ 2016 Sep 18(9) 549-552
• Systemic Treatment Strategies for Patients with Hereditary Breast Cancer Syndromes.  
  Parkes Amanda et al. The oncologist 2017 May
• A Retrospective Exploration of the Impact of the 'Angelina Jolie Effect' on the Single State-Wide Familial Cancer Program in Perth, Western Australia. 
  Freedman Rebecca et al. Journal of genetic counseling 2017 Feb 26(1) 52-62
• Adherence to Recommended Risk Management among Unaffected Women with a BRCA Mutation.  
  Buchanan Adam H et al. Journal of genetic counseling 2017 Feb 26(1) 79-92

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