herenciageneticayenfermedad: BioEdge: Frankenstein: the real experiments that inspired the fictional science

domingo, 4 de noviembre de 2018

BioEdge: Frankenstein: the real experiments that inspired the fictional science

BioEdge: Frankenstein: the real experiments that inspired the fictional science

Bioedge

Frankenstein: the real experiments that inspired the fictional science

by Iwan Morus | 2 Nov 2018 |

On January 17, 1803, a young man named George Forster was hanged for murder at Newgate prison in London. After his execution, as often happened, his body was carried ceremoniously across the city to the Royal College of Surgeons, where it would be publicly dissected. What actually happened was rather more shocking than simple dissection though. Forster was going to be electrified.

The experiments were to be carried out by the Italian natural philosopher Giovanni Aldini, the nephew of Luigi Galvani, who discovered “animal electricity” in 1780, and for whom the field of galvanism is named. With Forster on the slab before him, Aldini and his assistants started to experiment. The Times newspaper reported:

On the first application of the process to the face, the jaw of the deceased criminal began to quiver, the adjoining muscles were horribly contorted, and one eye was actually opened. In the subsequent part of the process, the right hand was raised and clenched, and the legs and thighs were set in motion.

It looked to some spectators “as if the wretched man was on the eve of being restored to life.”

By the time Aldini was experimenting on Forster the idea that there was some peculiarly intimate relationship between electricity and the processes of life was at least a century old. Isaac Newton speculated along such lines in the early 1700s. In 1730, the English astronomer and dyer Stephen Gray demonstrated the principle of electrical conductivity. Gray suspended an orphan boy on silk cords in mid air, and placed a positively charged tube near the boy’s feet, creating a negative charge in them. Due to his electrical isolation, this created a positive charge in the child’s other extremities, causing a nearby dish of gold leaf to be attracted to his fingers.

In France in 1746 Jean Antoine Nollet entertained the court at Versailles by causing a company of 180 royal guardsmen to jump simultaneously when the charge from a Leyden jar (an electrical storage device) passed through their bodies.

It was to defend his uncle’s theories against the attacks of opponents such as Alessandro Volta that Aldini carried out his experiments on Forster. Volta claimed that “animal” electricity was produced by the contact of metals rather than being a property of living tissue, but there were several other natural philosophers who took up Galvani’s ideas with enthusiasm. Alexander von Humboldt experimented with batteries made entirely from animal tissue. Johannes Ritter even carried out electrical experiments on himself to explore how electricity affected the sensations.

**Actor Boris Karloff as Frankenstein’s monster, 1935. Wikimedia**

The idea that electricity really was the stuff of life and that it might be used to bring back the dead was certainly a familiar one in the kinds of circles in which the young Mary Wollstonecraft Shelley – the author of Frankenstein – moved. The English poet, and family friend, Samuel Taylor Coleridge was fascinated by the connections between electricity and life. Writing to his friend the chemist Humphry Davy after hearing that he was giving lectures at the Royal Institution in London, he told him how his “motive muscles tingled and contracted at the news, as if you had bared them and were zincifying the life-mocking fibres”. Percy Bysshe Shelley himself – who would become Wollstonecraft’s husband in 1816 – was another enthusiast for galvanic experimentation.

Vital knowledge

Aldini’s experiments with the dead attracted considerable attention. Some commentators poked fun at the idea that electricity could restore life, laughing at the thought that Aldini could “make dead people cut droll capers”. Others took the idea very seriously. Lecturer Charles Wilkinson, who assisted Aldini in his experiments, argued that galvanism was “an energising principle, which forms the line of distinction between matter and spirit, constituting in the great chain of the creation, the intervening link between corporeal substance and the essence of vitality”.

In 1814 the English surgeon John Abernethy made much the same sort of claim in the annual Hunterian lecture at the Royal College of Surgeons. His lecture sparked a violent debate with fellow surgeon William Lawrence. Abernethy claimed that electricity was (or was like) the vital force while Lawrence denied that there was any need to invoke a vital force at all to explain the processes of life. Both Mary and Percy Shelley certainly knew about this debate – Lawrence was their doctor.

By the time Frankenstein was published in 1818, its readers would have been familiar with the notion that life could be created or restored with electricity. Just a few months after the book appeared, the Scottish chemist Andrew Ure carried out his own electrical experiments on the body of Matthew Clydesdale, who had been executed for murder. When the dead man was electrified, Ure wrote, “every muscle in his countenance was simultaneously thrown into fearful action; rage, horror, despair, anguish, and ghastly smiles, united their hideous expression in the murderer’s face”.

Ure reported that the experiments were so gruesome that “several of the spectators were forced to leave the apartment, and one gentleman fainted”. It is tempting to speculate about the degree to which Ure had Mary Shelley’s recent novel in mind as he carried out his experiments. His own account of them was certainly quite deliberately written to highlight their more lurid elements.

Frankenstein might look like fantasy to modern eyes, but to its author and original readers there was nothing fantastic about it. Just as everyone knows about artificial intelligence now, so Shelley’s readers knew about the possibilities of electrical life. And just as artificial intelligence (AI) invokes a range of responses and arguments now, so did the prospect of electrical life – and Shelley’s novel – then.

The science behind Frankenstein reminds us that current debates have a long history – and that in many ways the terms of our debates now are determined by it. It was during the 19th century that people started thinking about the future as a different country, made out of science and technology. Novels such as Frankenstein, in which authors made their future out of the ingredients of their present, were an important element in that new way of thinking about tomorrow.

Thinking about the science that made Frankenstein seem so real in 1818 might help us consider more carefully the ways we think now about the possibilities – and the dangers – of our present futures.

Iwan Morus, Professor of History, Aberystwyth University. This article is republished from The Conversation under a Creative Commons license. Read the original article.

Sunday, November 4, 2018

It happened so long ago that the exact details are dim in my mind, but I seem to remember that a nominee for the US Supreme Court nearly failed to score his dream job because of an alleged crime of attempted rape when he was a 17-year-old high school student. There was a huge controversy, wasn’t there? Demonstrations, twitterstorms, talking heads across the nation in a frenzy, politicians grandstanding...

Of course times were different way back then and public figures were held to a higher moral and legal standard. As the saying goes, "The past is a foreign country; they do things differently there." Nonetheless it is disturbing to read that the Democratic candidate for the governor of California, Gavin Newsom, casually told a journalist for The New Yorker that he assisted his mother to commit suicide in 2002. Assisting a suicide was a crime in California in 2002– and it still is if you are not a doctor. And at the time Newsom was not a callow teenager, but a member of the San Francisco Board of Supervisors.

The odd thing about this is that there has been almost no reaction. Assisting a suicide is just as much a crime as attempted rape and in this case Newsom has admitted that he did it. You would think that at least his Republican opponent would seize upon this blithe admission as a golden opportunity to knock off Newsom's Kennedy-esque halo.

But no one seems to care. What more do you need to show that assisted suicide has been normalised in California?