Allergy, Asthma & Clinical Immunology
The official journal of CSACI
Volume 14 Supplement 2
Practical guide for allergy and immunology in Canada 2018
Reviews
An extensive update to the prominent and widely-popular Practical Guide for Allergy and Immunology in Canada published in 2011, this broad-ranging supplement is designed to provide all healthcare professionals with a comprehensive, yet easy-to-follow, series of peer-reviewed articles focussed on all of the common conditions dealt with in the field of allergy and immunology.
Edited by Harold Kim, Richard Warrington and Wade Watson
Declarations
Publication of this supplement has been supported by AstraZeneca, Boehringer Ingelheim, CSL Behring Canada Inc., MEDA Pharmaceuticals Ltd., Merck Canada Inc., Pfizer Canada Inc., Shire Pharma Canada ULC, Stallergenes Greer Canada, Takeda Canada, Teva Canada Innovation, Aralez Tribute and Pediapharm. The articles have undergone the journal's standard peer review process for supplements. All Supplement Editors confirm they were not involved in the review process of papers that they are listed as authors.
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An introduction to immunology and immunopathology
Beyond structural and chemical barriers to pathogens, the immune system has two fundamental lines of defense: innate immunity and adaptive immunity. Innate immunity is the first immunological mechanism for fig...14(Suppl 2):49Allergy, Asthma & Clinical Immunology 2018Asthma
Asthma is the most common respiratory disorder in Canada. Despite significant improvement in the diagnosis and management of this disorder, the majority of Canadians with asthma remain poorly controlled. In mo...14(Suppl 2):50Allergy, Asthma & Clinical Immunology 2018Allergic rhinitis
Allergic rhinitis is a common disorder that is strongly linked to asthma and conjunctivitis. It is usually a long-standing condition that often goes undetected in the primary-care setting. The classic symptoms...14(Suppl 2):51Allergy, Asthma & Clinical Immunology 2018Atopic dermatitis
Atopic dermatitis (AD) is a common, chronic skin disorder that can significantly impact the quality of life of affected individuals as well as their families. Although the pathogenesis of the disorder is not c...14(Suppl 2):52Allergy, Asthma & Clinical Immunology 2018Allergen-specific immunotherapy
Allergen-specific immunotherapy is a potentially disease-modifying therapy that is effective for the treatment of allergic rhinitis/conjunctivitis, allergic asthma and stinging insect hypersensitivity. However...14(Suppl 2):53Allergy, Asthma & Clinical Immunology 2018Anaphylaxis
Anaphylaxis is an acute, potentially fatal systemic allergic reaction with varied mechanisms and clinical presentations. Although prompt recognition and treatment of anaphylaxis are imperative, both patients a...14(Suppl 2):54Allergy, Asthma & Clinical Immunology 2018IgE-mediated food allergy
Food allergy is defined as an adverse immunologic response to a food protein. Food-related reactions are associated with a broad range of signs and symptoms that may involve any body system, including the skin...14(Suppl 2):55Allergy, Asthma & Clinical Immunology 2018Non-IgE-mediated food hypersensitivity
Non-immunoglobulin E (IgE)-mediated food hypersensitivity includes a spectrum of disorders that predominantly affect the gastrointestinal tract. This review will focus on the following more common non-IgE-medi...14(Suppl 2):56Allergy, Asthma & Clinical Immunology 2018Early introduction of foods to prevent food allergy
Food allergy is a growing public health problem, and in many affected individuals, the food allergy begins early in life and persists as a lifelong condition (e.g., peanut allergy). Although early clinical pra...14(Suppl 2):57Allergy, Asthma & Clinical Immunology 2018Eosinophilic esophagitis
Eosinophilic esophagitis (EoE) is an atopic condition of the esophagus that has become increasingly recognized over the last 15 years. Diagnosis of the disorder is dependent on the patient’s clinical manifesta...14(Suppl 2):58Allergy, Asthma & Clinical Immunology 2018Urticaria and angioedema
Urticaria (hives) is a common disorder that often presents with angioedema (swelling that occurs beneath the skin). It is generally classified as acute or chronic. Second-generation, non-sedating, non-impairin...14(Suppl 2):59Allergy, Asthma & Clinical Immunology 2018Drug allergy
Drug allergy encompasses a spectrum of immunologically-mediated hypersensitivity reactions with varying mechanisms and clinical presentations. This type of adverse drug reaction not only affects patient qualit...14(Suppl 2):60Allergy, Asthma & Clinical Immunology 2018Primary immunodeficiency
Primary immunodeficiency disorder (PID) refers to a large heterogeneous group of disorders that result from defects in immune system development and/or function. PIDs are broadly classified as disorders of ada...14(Suppl 2):61Allergy, Asthma & Clinical Immunology 2018
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