domingo, 2 de agosto de 2020

Coronavirus [NEW TOPIC PAGE]

Hot Topics of the Day|PHGKB

Coronavirus

How does SARS-CoV-2 cause COVID-19?
NJ Matheson, et al, Science, July 31, 2020
As with all coronaviruses, SARS-CoV-2 cell entry is dependent on its 180-kDa spike (S) protein, which mediates two essential events: binding to ACE2 by the amino-terminal region, and fusion of viral and cellular membranes through the carboxyl-terminal region.
Swabs Collected by Patients or Health Care Workers for SARS-CoV-2 Testing.
Tu Yuan-Po et al. The New England journal of medicine 2020 07 (5) 494-496
Our study shows the clinical usefulness of tongue, nasal, or mid-turbinate samples collected by patients as compared with nasopharyngeal samples collected by health care workers for the diagnosis of Covid-19.
Covid's Color Line - Infectious Disease, Inequity, and Racial Justice.
Evans Michele K et al. The New England journal of medicine 2020 Jul (5) 408-410
Glucocorticoids probably reduce mortality and mechanical ventilation in patients with covid-19 compared with standard care. The effectiveness of most interventions is uncertain because most of the randomised controlled trials so far have been small and have important study limitations.

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