Coronavirus [NEW TOPIC PAGE]

Hot Topics of the Day|PHGKB

 Coronavirus

What We Know About COVID-19’s Effects on Child and Maternal Health
NIH Director's Blog, July 31, 2020 

Association between Alzheimer's disease and COVID-19: A bidirectional Mendelian randomization
D Liu et al, MEDRXIV, July 30, 2020

Initial evaluation of a mobile SARS-CoV-2 RT-LAMP testing strategy
C Newman et al, MEDRXIV, July 30, 2020

How does SARS-CoV-2 cause COVID-19?
NJ Matheson, et al, Science, July 31, 2020

As with all coronaviruses, SARS-CoV-2 cell entry is dependent on its 180-kDa spike (S) protein, which mediates two essential events: binding to ACE2 by the amino-terminal region, and fusion of viral and cellular membranes through the carboxyl-terminal region.

Swabs Collected by Patients or Health Care Workers for SARS-CoV-2 Testing.
Tu Yuan-Po et al. The New England journal of medicine 2020 07 (5) 494-496

Our study shows the clinical usefulness of tongue, nasal, or mid-turbinate samples collected by patients as compared with nasopharyngeal samples collected by health care workers for the diagnosis of Covid-19.

Covid's Color Line - Infectious Disease, Inequity, and Racial Justice.
Evans Michele K et al. The New England journal of medicine 2020 Jul (5) 408-410

Drug treatments for covid-19: living systematic review and network meta-analysis
RAC Siemieniuk et al, BMJ, July 30, 2020

Glucocorticoids probably reduce mortality and mechanical ventilation in patients with covid-19 compared with standard care. The effectiveness of most interventions is uncertain because most of the randomised controlled trials so far have been small and have important study limitations.