Coronavirus [NEW TOPIC PAGE]

Hot Topics of the Day|PHGKB

 Coronavirus

Employing a Systematic Approach to Biobanking and Analyzing Genetic and Clinical Data for Advancing COVID-19 Research
S Daga et al, MEDRXIV, August 14, 2020

Mobility network modeling explains higher SARS-CoV-2 infection rates among disadvantaged groups and informs reopening strategies
SY Chang et al, MEDRXIV, August 14, 2020

We simulate the spread of SARS-CoV-2 from March 1 - May 2, 2020 among a population of 98 million people in 10 of the largest US metropolitan areas. We show that by integrating mobility networks, even a relatively simple epidemiological model can accurately capture the case trajectory despite dramatic changes in population behavior due to the virus.

Quantitative analysis of SARS-CoV-2 RNA from wastewater solids in communities with low COVID-19 incidence and prevalence
PM D'Aoust al, MEDRXIV, August 14, 2020

The Plan That Could Give Us Our Lives Back The U.S. has never had enough coronavirus tests. Now a group of epidemiologists, economists, and dreamers is plotting a new strategy to defeat the virus, even before a vaccine is found.
R Meyer et al, The Atlantic, August 2020

Host polymorphisms may impact SARS-CoV-2 infectivity
P Brest et al, Trends in Genetics, August 10, 2020

Based on a broad public database compilation, we support the hypothesis that germinal polymorphisms may regulate the expression of the SARS-CoV-2 cellular target itself and proteases controlling the process of its shedding or, conversely, its internalization. A genetic influence on individual susceptibility to COVID-19 infection is strongly suspected.