PARP inhibitors combined with ionizing radiation induce different effects in melanoma cells and healthy fibroblasts | BMC Cancer | Full Text

PARP inhibitors combined with ionizing radiation induce different effects in melanoma cells and healthy fibroblasts | BMC Cancer | Full Text

PARP inhibitors combined with ionizing radiation induce different effects in melanoma cells and healthy fibroblasts

PARP inhibitors niraparib and talazoparib are FDA approved for special cases of breast cancer. PARP is an interesting repair protein which is frequently affected in cancer cells. We studied the combined action...

Authors:Verena Weigert, Tina Jost, Markus Hecht, Ilka Knippertz, Lucie Heinzerling, Rainer Fietkau and Luitpold V. Distel

Citation:BMC Cancer 2020 20:775

Content type:Research article

 

Published on: 18 August 2020

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