martes, 11 de junio de 2019

How animal models are helping us understand migraine and cluster headache symptoms - On Medicine

How animal models are helping us understand migraine and cluster headache symptoms - On Medicine

Anne-Sophie Wattiez & Doga Vuralli

Anne-Sophie Wattiez is a Research Scientist in Andrew Russo’s laboratory at the University of Iowa. Her research focuses on elucidating the pathophysiology of migraine and post-traumatic headaches using behavioral and molecular assays. This research is supported by grants from the VA, DOD and NIH.

Doga Vuralli obtained her basic medical degree and training at Hacettepe University, Faculty of Medicine, Ankara, Turkey. She completed her neurology residency and pain medicine fellowship at Gazi University, Ankara, Turkey. She is interested in both clinical and basic research studies in the headache field, including the electrophysiological studies in headache disorders and the studies on the pathophysiology of migraine. She is a fellow of the European Board of Neurology and a member of the International Headache Society.


How animal models are helping us understand migraine and cluster headache symptoms

March is an important month for raising awareness of primary headache disorders and the research being done to understand and treat them, with Brain Awareness Week 11th – 17th and Cluster Headache Awareness Day on the 21st. To coincide with these important events we invited Anne-Sophie Wattiez and Doga Vuralli to talk about their recent review in The Journal of Headache and Pain which explores how we can use animal models to better understand the pathophysiology of headache disorders and develop potential treatments.

Primary headache disorders such as migraine are very common and their mechanisms are not entirely understood. Aside from being painful, headache disorders are also disabling. Migraine has recently been ranked as the second highest cause of years lost due to disability worldwide. Cluster headache is another disabling primary headache and extremely painful form of trigeminal autonomic cephalalgia.

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