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• Quick and affordable saliva-based COVID-19 test developed by Yale scientists receives FDA Emergency Use Authorization
  M Greenwood, Yale News, August 15, 2020
  
• SalivaDirect: Simple and sensitive molecular diagnostic test for SARS-CoV-2 surveillance
  CBF Vogels et al, MEDRXIV, August 2020
  
  Using saliva instead of respiratory swabs enables non-invasive frequent sampling and reduces the need for trained healthcare professionals during collection. Our test does not require nucleic acid preservatives at sample collection and replaces nucleic acid extraction with a simple proteinase K and heat treatment step.
• Employing a Systematic Approach to Biobanking and Analyzing Genetic and Clinical Data for Advancing COVID-19 Research
  S Daga et al, MEDRXIV, August 14, 2020
• Mobility network modeling explains higher SARS-CoV-2 infection rates among disadvantaged groups and informs reopening strategies
  SY Chang et al, MEDRXIV, August 14, 2020
  
  We simulate the spread of SARS-CoV-2 from March 1 - May 2, 2020 among a population of 98 million people in 10 of the largest US metropolitan areas. We show that by integrating mobility networks, even a relatively simple epidemiological model can accurately capture the case trajectory despite dramatic changes in population behavior due to the virus.
• Quantitative analysis of SARS-CoV-2 RNA from wastewater solids in communities with low COVID-19 incidence and prevalence
  PM D'Aoust al, MEDRXIV, August 14, 2020
• Host polymorphisms may impact SARS-CoV-2 infectivity
  P Brest et al, Trends in Genetics, August 10, 2020
  
  Based on a broad public database compilation, we support the hypothesis that germinal polymorphisms may regulate the expression of the SARS-CoV-2 cellular target itself and proteases controlling the process of its shedding or, conversely, its internalization. A genetic influence on individual susceptibility to COVID-19 infection is strongly suspected.
• A multimethod approach for county-scale geospatial analysis of emerging infectious diseases: a cross-sectional case study of COVID-19 incidence in Germany.
  Scarpone Christopher, et al. International journal of health geographics 2020 8 0. (1) 32
  
• COVID-19 Prediction Models and Unexploited Data.
  Santosh K C, et al. Journal of medical systems 2020 8 0. (9) 170
  
• Trove: Ontology-driven weak supervision for medical entity classification.
  Fries Jason A, et al. ArXiv 2020 8 0.
  
  
• An artificial intelligence system for predicting the deterioration of COVID-19 patients in the emergency department.
  Shamout Farah E, et al. ArXiv 2020 8 0.
  
• Transmission dynamics of Covid-19 in Italy, Germany and Turkey considering social distancing, testing and quarantine.
  Gul Serdar, et al. Journal of infection in developing countries 2020 7 0. (7) 713-720
  
• Machine learning-based CT radiomics method for predicting hospital stay in patients with pneumonia associated with SARS-CoV-2 infection: a multicenter study.
  Yue Hongmei, et al. Annals of translational medicine 2020 7 0. (14) 859
  
  
• A diagnostic genomic signal processing (GSP)-based system for automatic feature analysis and detection of COVID-19.
  Naeem Safaa M, et al. Briefings in bioinformatics 2020 8 0.
  
• Familial Clustering of COVID-19 Skin Manifestations.
  Tatu Alin Laurentiu, et al. Dermatologic therapy 2020 8 0. e14181
  
• Sequence-based prediction of SARS-CoV-2 vaccine targets using a mass spectrometry-based bioinformatics predictor identifies immunogenic T cell epitopes.
  Poran Asaf, et al. Genome medicine 2020 8 0. (1) 70
  
• Receptor utilization of angiotensin converting enzyme 2 (ACE2) indicates a narrower host range of SARS-CoV-2 than that of SARS-CoV.
  Wang Qiong, et al. Transboundary and emerging diseases 2020 8 0.
  
• SARS-CoV-2 infection, neuropathogenesis and transmission among deer mice: Implications for reverse zoonosis to New World rodents.
  Fagre Anna, et al. bioRxiv : the preprint server for biology 2020 8 0.
  
  
• mRNA induced expression of human angiotensin-converting enzyme 2 in mice for the study of the adaptive immune response to severe acute respiratory syndrome coronavirus 2.
  Hassert Mariah, et al. bioRxiv : the preprint server for biology 2020 8 0.
  
  
• A Rational Design of a Multi-Epitope Vaccine Against SARS-CoV-2 Which Accounts for the Glycan Shield of the Spike Glycoprotein.
  Martin William R, et al. ChemRxiv : the preprint server for chemistry 2020 8 0.
  
• IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection.
  Rosa Bruce A, et al. bioRxiv : the preprint server for biology 2020 8 0.
  
• Computational Hot-Spot Analysis of the SARS-CoV-2 Receptor Binding Domain / ACE2 Complex.
  Rosario Pedro A, et al. bioRxiv : the preprint server for biology 2020 8 0.
  
• IFN- γ and TNF- α drive a CXCL10 + CCL2 + macrophage phenotype expanded in severe COVID-19 and other diseases with tissue inflammation.
  Zhang Fan, et al. bioRxiv : the preprint server for biology 2020 8 0.
  
• Comparison of media and standards for SARS-CoV-2 RT-qPCR without prior RNA preparation.
  Ragan Katherine B, et al. medRxiv : the preprint server for health sciences 2020 8 0.
  
• Viable SARS-CoV-2 in the air of a hospital room with COVID-19 patients.
  Lednicky John A, et al. medRxiv : the preprint server for health sciences 2020 8 0.
  
  
• De novo design of ACE2 protein decoys to neutralize SARS-CoV-2.
  Linsky Thomas W, et al. bioRxiv : the preprint server for biology 2020 8 0.
  
• Similarity between mutation spectra in hypermutated genomes of rubella virus and in SARS-CoV-2 genomes accumulated during the COVID-19 pandemic.
  Klimczak Leszek J, et al. bioRxiv : the preprint server for biology 2020 8 0.
  
• Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020.
  Alm Erik, et al. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 2020 8 0. (32)
  
  
• One-step nested RT-PCR for COVID-19 detection: A flexible, locally developed test for SARS-CoV2 nucleic acid detection.
  Meza-Robles Carmen, et al. Journal of infection in developing countries 2020 7 0. (7) 679-684
  
• Geographic and Genomic Distribution of SARS-CoV-2 Mutations.
  Mercatelli Daniele, et al. Frontiers in microbiology 2020 0 0. 1800
  
  
• Women are most affected by pandemics - lessons from past outbreaks.
  Wenham Clare, et al. Nature 2020 0 0. (7815) 194-198
  
  

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Disclaimer: Articles listed in the Public Health Knowledge Base are selected by the CDC Office of Public Health Genomics to provide current awareness of the literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the update, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.