T cell infiltration and upregulation of MHCII in microglia leads to accelerated neuronal loss in an α-synuclein rat model of Parkinson’s disease | Journal of Neuroinflammation | Full Text

T cell infiltration and upregulation of MHCII in microglia leads to accelerated neuronal loss in an α-synuclein rat model of Parkinson’s disease | Journal of Neuroinflammation | Full Text

T cell infiltration and upregulation of MHCII in microglia leads to accelerated neuronal loss in an α-synuclein rat model of Parkinson’s disease

Parkinson’s disease (PD) is the second most prevalent movement disorder characterized by up to 80% loss of dopamine (DA) neurons and accumulation of Lewy body deposits composed of α-synuclein (α-syn). Accumula...

Authors:Meena S. Subbarayan, Charles Hudson, Lauren D. Moss, Kevin R. Nash and Paula C. Bickford

Citation:Journal of Neuroinflammation 2020 17:242

Content type:Research

 

Published on: 15 August 2020

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