Incidental findings|https://phgkb.cdc.gov/GAPPKB/phgHome.do|Incidental findings

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Last Posted: Apr 26, 2017

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• Stakeholder views on secondary findings in whole-genome and whole-exome sequencing: a systematic review of quantitative and qualitative studies. 
  Mackley Michael P et al. Genetics in medicine : official journal of the American College of Medical Genetics 2017 Mar 19(3) 283-293
• How do clinical genetics consent forms address the familial approach to confidentiality and incidental findings? A mixed-methods study.  
  Dheensa Sandi et al. Familial cancer 2017 Apr
• Defining categories of actionability for secondary findings in next-generation sequencing.  
  Moret Celine et al. Journal of medical ethics 2016 Dec
• Choices for return of primary and secondary genomic research results of 790 members of families with Mendelian disease.  
  Fiallos Katie et al. European journal of human genetics : EJHG 2017 Mar
• Development and Validation of Clinical Whole-Exome and Whole-Genome Sequencing for Detection of Germline Variants in Inherited Disease.  
  Hegde Madhuri et al. Archives of pathology & laboratory medicine 2017 Mar
• Discussing molecular testing in oncology care: Comparing patient and physician information preferences.  
  Pinheiro Ana P M et al. Cancer 2017 Jan
• Ethical signposts for clinical geneticists in secondary variant and incidental finding disclosure discussions.  
  Christenhusz Gabrielle M et al. Medicine, health care, and philosophy 2015 Aug 18(3) 361-70
• Incidental findings of uncertain significance: To know or not to know--that is not the question.  
  Hofmann Bjørn et al. BMC medical ethics 2016 Feb 1713
• Incidentalome from Genomic Sequencing: A Barrier to Personalized Medicine?  
  Jamuar Saumya Shekhar et al. EBioMedicine 2016 Mar 5211-6
• The fiduciary relationship model for managing clinical genomic "incidental" findings.  
  Lázaro-Muñoz Gabriel et al. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics 2014 42(4) 576-89
• Will Unanticipated Genetic Mutations Lead to Subsequent Disease?  
  Brigham and Women's Hospital press release, November 9, 2016
• Clinical and Pathological Characteristics of Incidental Diagnostic Early Occult Malignancy After Risk-Reducing Salpingo-Oophorectomy in BRCA Mutation Carriers.  
  Lavie Ofer et al. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2016 Feb 26(2) 233-9
• Reporting Incidental Findings in Clinical Whole Exome Sequencing: Incorporation of the 2013 ACMG Recommendations into Current Practices of Genetic Counseling.  
  Smith Lacey A et al. Journal of genetic counseling 2015 Aug 24(4) 654-62
• Consideration surrounding incidental findings throughout multigene panel testing in cancer genetics.  
  Grandval P et al. Clinical genetics 2016 Feb 89(2) 267-8
• Ethical, Legal, and Social Implications of Personalized Genomic Medicine Research: Current Literature and Suggestions for the Future.  
  Callier Shawneequa L et al. Bioethics 2016 Nov 30(9) 698-705
• PIGSR: A Preference Instrument for Genomics Secondary Results  
  CSER Consortium Online Tool

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