Incidental findings ► Public Health Genomics Knowledge Base (v1.0)

Public Health Genomics Knowledge Base (v1.0)








Last Updated: May 19, 2016

• Ethical considerations in biobanks: how a public health ethics perspective sheds new light on old controversies.
  Virani Alice Hawkins et al. Journal of genetic counseling 2015 Jun 24(3) 428-32
• The challenge of consent in clinical genome-wide testing.
  Burke Katherine et al. Archives of disease in childhood 2016 Apr
• Research participant interest in primary, secondary, and incidental genomic findings.
  Loud Jennifer T et al. Genetics in medicine : official journal of the American College of Medical Genetics 2016 Apr
• Patient preferences regarding incidental genomic findings discovered during tumor profiling.
  Yushak Melinda L et al. Cancer 2016 Mar
• Ethical Considerations for the Return of Incidental Findings in Ophthalmic Genomic Research.
  Souzeau Emmanuelle et al. Translational vision science & technology 2016 Feb 5(1) 3
• Patients' views on incidental findings from clinical exome sequencing.
  Clift Kristin E et al. Applied & translational genomics 2015 Mar 438-43
• Incidental Findings: The Importance of Pretest Counseling.
  Buchtel Kathryn M et al. Pediatric neurology briefs 2015 Dec 29(12) 91
• A Clinical Service to Support the Return of Secondary Genomic Findings in Human Research
  AJ Darnell et al, AM J Human Genetics, March 3, 2016
• Incidental findings of uncertain significance: To know or not to know - that is not the question.
  Hofmann Bjørn et al. BMC medical ethics 2016 (1) 13
• Generating a taxonomy for genetic conditions relevant to reproductive planning.
  Korngiebel Diane M et al. American journal of medical genetics. Part A 2016 Mar 170(3) 565-73
• Oncologists' and cancer patients' views on whole-exome sequencing and incidental findings: results from the CanSeq study.
  Gray Stacy W et al. Genetics in medicine : official journal of the American College of Medical Genetics 2016 Feb
• Improving performance of multigene panels for genomic analysis of cancer predisposition.
  Shirts Brian H et al. Genetics in medicine : official journal of the American College of Medical Genetics 2016 Feb
• Association of Arrhythmia-Related Genetic Variants With Phenotypes Documented in Electronic Medical Records.
  Van Driest Sara L et al. JAMA 2016 Jan 315(1) 47-57
• In Guanine We Trust: Genetic Testing and the Sense of Coherence.
  DuBois James M et al. Narrative inquiry in bioethics 2015 5(3) 237-44
• Automatic Placement of Genomic Research Results in Medical Records: Do Researchers Have a Duty? Should Participants Have a Choice?
  Prince Anya E R et al. The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics 2015 Dec 43(4) 827-42
• You have a possibly faulty gene. Should your doctor tell you?
  By Patrick Skerrett, STAT, January 5, 2016
• Next-generation sequencing using a pre-designed gene panel for the molecular diagnosis of congenital disorders in pediatric patients.
  Lim Eileen C P et al. Human genomics 2015 9(1) 33
• Statement of principles on the return of research results and incidental findings in paediatric research: a multi-site consultative process.
  Published on 2015 by The Network of Applied Genetic Medicine
• Incidental Findings with Genomic Testing: Implications for Genetic Counseling Practice.
  Roche Myra I et al. Current genetic medicine reports 3(4) 166-176
• Precision medicine ethics: selected issues and developments in next-generation sequencing, clinical oncology, and ethics.
  Fiore Robin N et al. Current opinion in oncology 2015 Nov
• Review of Commercially Available Epilepsy Genetic Panels.
  Chambers Chelsea et al. Journal of genetic counseling 2015 Nov
• To disclose, or not to disclose? Context matters.
  Rahimzadeh Vasiliki et al. European journal of human genetics : EJHG 2015 Mar 23(3) 279-84
• Genetics: Fluent in DNA.
  Eisenstein Michael et al. Nature 2015 Oct 526(7571) 151-2
• Returning a Research Participant's Genomic Results to Relatives: Analysis and Recommendations.
  Published on 2015 by Expert panel
• Molecular analysis of clinical isolates previously diagnosed as Mycobacterium intracellulare reveals incidental findings of "Mycobacterium indicus pranii" genotypes in human lung infection.
  Kim Su-Young, Park Hye Yun, Jeong Byeong-Ho, Jeon Kyeongman, Huh Hee Jae, Ki Chang-Seok, Lee Nam Yong, Han Seung-Jung, Shin Sung Jae, Koh Won-Jung.BMC infectious diseases 2015 (1) 406
• Minimum information for reporting next generation sequence genotyping (MIRING): Guidelines for reporting HLA and KIR genotyping via next generation sequencing.
  Mack Steven J et al. Human immunology 2015 Sep
• Attitudes of the general public towards the disclosure of individual research results and incidental findings from biobank genomic research in Australia.
  Fleming J et al. Intern Med J 2015 Sep 21.
• A protocol for the identification and validation of novel genetic causes of kidney disease.
  Mallett Andrew, et al. BMC nephrology 2015 0 (1) 152
• The clinical application of genome-wide sequencing for monogenic diseases in Canada: Position Statement of the Canadian College of Medical Geneticists.
  Published on 2015 by Canadian College of Medical Geneticists
• College of American Pathologists' Laboratory Standards for Next-Generation Sequencing Clinical Tests.
  Published on 2015 by College of American Pathologists

• CDC Information (1)
• CDC-Authored Pub (2)

• Human (12)
• Pathogen (0)

• Human (42)
• Pathogen (1)

• Guidelines (6)
• Tier Table (0)
• Synthesis (7)

Relevant Resources

• Cancer Genomics and Epidemiology Navigator (CGEN)
• Genetics and Genomics Competencies Center (G2C2)
• NIH Genetic Testing Registry
• NIH MedGen Database
• Online Mendelian Inheritance in Man (OMIM)
• PharmGKB