Pollution and epigenetics

Pollution and Epigenetics

About this collection

From diesel particulates to endocrine disruptors, asbestos, heavy metals to molecules like bisphenol A (BPA), it is becoming increasingly clear that man’s propensity to pollute has significant consequences on human health. Moreover, strong evidence now links such pollution to changes within our epigenomes. In this new thematic series in Clinical Epigenetics, we explore the causes and consequences of pollution on the epigenome, how this may have effects not only on the epigenetics of the individual exposed to such pollution, but also review how this may be further exacerbated by downstream or “transgenerational” inheritance of these epigenetic changes.

Guest Editors: Steven Gray and Wim Vanden Berghe

Submit your research on pollution and epigenetics to Clinical Epigenetics.

1. Content Type:Review

   Prenatal epigenetics diets play protective roles against environmental pollution

   It is thought that germ cells and preimplantation embryos during development are most susceptible to endogenous and exogenous environmental factors because the epigenome in those cells is undergoing dramatic e...

   Authors:Shizhao Li, Min Chen, Yuanyuan Li and Trygve O. Tollefsbol

   Citation:Clinical Epigenetics 2019 11:82

   Published on: 16 May 2019

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2. Content Type:Research

   Genome-wide DNA methylation and long-term ambient air pollution exposure in Korean adults

   Ambient air pollution is associated with numerous adverse health outcomes, but the underlying mechanisms are not well understood; epigenetic effects including altered DNA methylation could play a role. To eval...

   Authors:Mi Kyeong Lee, Cheng-Jian Xu, Megan U. Carnes, Cody E. Nichols, James M. Ward, Sung Ok Kwon, Sun-Young Kim, Woo Jin Kim and Stephanie J. London

   Citation:Clinical Epigenetics 2019 11:37

   Published on: 28 February 2019

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3. Content Type:Review

   Epigenetic impacts of maternal tobacco and e-vapour exposure on the offspring lung

   In utero exposure to tobacco products, whether maternal or environmental, have harmful effects on first neonatal and later adult respiratory outcomes. These effects have been shown to persist across subsequent...

   Authors:Razia Zakarya, Ian Adcock and Brian G. Oliver

   Citation:Clinical Epigenetics 2019 11:32

   Published on: 19 February 2019

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4. Content Type:Research

   Aberrant methylation of Pax3 gene and neural tube defects in association with exposure to polycyclic aromatic hydrocarbons

   Neural tube defects (NTDs) are common and severe congenital malformations. Pax3 is an essential gene for neural tube closure in mice but it is unknown whether altered expression or methylation of PAX3 contributes...

   Authors:Shanshan Lin, Aiguo Ren, Linlin Wang, Chloe Santos, Yun Huang, Lei Jin, Zhiwen Li and Nicholas D. E. Greene

   Citation:Clinical Epigenetics 2019 11:13

   Published on: 21 January 2019

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