viernes, 14 de junio de 2019

BMC Cancer | Articles

BMC Cancer | Articles



BMC Cancer

  1. Study Protocol

    Detection of circulating tumor DNA (ctDNA) is a promising method for postoperative surveillance of lung cancer. However, relatively low positive rate in early stage patients restricts its application. Aberrant...
    Authors:Guannan Kang, Kezhong Chen, Fan Yang, Shannon Chuai, Heng Zhao, Kai Zhang, Bingsi Li, Zhihong Zhang and Jun Wang
    Citation:BMC Cancer 2019 19:579
    Published on: 
  2. Content Type:Research Article

    Eribulin mesylate is a nontaxane microtubule dynamics inhibitor approved for second-line (European Union) or third-line (United States) treatment of metastatic breast cancer. Two phase 2 single trials, evaluat...
    Authors:Lee Schwartzberg, Kristi McIntyre, Sharon Wilks, Shannon Puhalla, Joyce O’Shaughnessy, Erhan Berrak, Yaohua He and Linda Vahdat
    Citation:BMC Cancer 2019 19:578
    Published on: 
  3. Content Type:Research Article

    Triple-negative breast cancer (TNBC) is a type of breast cancer with a high degree of malignancy. Because of the remarkable biological characteristics of high invasion, metastasis and recurrence, TNBC is often...
    Authors:Cheng Wang, Cheng Xu, Ruijie Niu, Guangfu Hu, Zhangyuan Gu and Zhigang Zhuang
    Citation:BMC Cancer 2019 19:577
    Published on: 
  4. Content Type:Research Article

    Cell division cycle associated 2 (CDCA2), upregulated in lung adenocarcinoma and oral squamous cell carcinoma, may be related to some malignant diseases. Nevertheless, its role in colorectal cancer (CRC) remai...
    Authors:Yifei Feng, Wenwei Qian, Yue Zhang, Wen Peng, Jie Li, Qiou Gu, Dongjian Ji, Zhiyuan Zhang, Qingyuan Wang, Dongsheng Zhang and Yueming Sun
    Citation:BMC Cancer 2019 19:576
    Published on: 
  5. Content Type:Research Article

    Distant metastases frequently occur in gastroenteropancreatic neuroendocrine tumors. If hepatic surgery is not feasible, patients are treated with somatostatin analogs. However, the underlying mechanisms of ac...
    Authors:Florian Bösch, Alexandr V. Bazhin, Sabine Heublein, Katharina Brüwer, Thomas Knösel, Florian P. Reiter, Christoph J. Auernhammer, Markus O. Guba, Christine Spitzweg, Jens Werner and Martin K. Angele
    Citation:BMC Cancer 2019 19:575
    Published on: 
  6. Content Type:Research Article

    Thyroid transcription factor (TTF)-1 expression is a diagnostic marker and a good prognostic indicator for lung adenocarcinoma. However, its good prognostic ability might be due to epidermal growth factor rece...
    Authors:Ji Young Park, Seung Hun Jang, Hwan Il Kim, Joo-Hee Kim, Sunghoon Park, Yong Il Hwang, Ki-Suck Jung, Jinwon Seo, Chang Youl Lee, Yousang Ko and Yong-Bum Park
    Citation:BMC Cancer 2019 19:574
    Published on: 
  7. Content Type:Research Article

    Treatment options in metastatic breast cancer are limited. New therapies preferable with predictive biomarkers are needed. The aim of these trials was to investigate if gene copy number of the topoisomerase 1 ...
    Authors:Iben Kümler, Eva Balslev, Jan Stenvang, Nils Brünner, Bent Ejlertsen, Erik Hugger Jakobsen and Dorte Lisbet Nielsen
    Citation:BMC Cancer 2019 19:573
    Published on: 
  8. Content Type:Study Protocol

    In men with a rising PSA following radical prostatectomy, salvage radiation therapy (SRT) offers a second chance for cure. Hormonal therapy can be combined with SRT in order to increase prostate tumor control,...
    Authors:Roche Kapoor, Matthew P. Deek, Riley McIntyre, Natasha Raman, Megan Kummerlowe, Iyah Chen, Matt Gaver, Hao Wang, Sam Denmeade, Tamara Lotan, Channing Paller, Mark Markowski, Michael Carducci, Mario Eisenberger, Tomasz M. Beer, Daniel Y. Song…
    Citation:BMC Cancer 2019 19:572
    Published on: 
  9. Content Type:Research Article

    Using a pathway-focused approach, we aimed to provide a subgroup-specific basis for finding novel therapeutic strategies and further refinement of the risk stratification in pediatric medulloblastoma.
    Authors:Ae Kyung Park, Ji Yeoun Lee, Heesun Cheong, Vijay Ramaswamy, Sung-Hye Park, Marcel Kool, Ji Hoon Phi, Seung Ah Choi, Florence Cavalli, Michael D. Taylor and Seung-Ki Kim
    Citation:BMC Cancer 2019 19:571
    Published on: 
  10. Content Type:Research Article

    In response to the increasing cancer prevalence and the evolving health service landscape across the public and private health sectors in Australia, this study aimed to map cancer services and identify factors...
    Authors:Jennifer Hunter, Caroline Smith, Geoff P. Delaney, Kate Templeman, Suzanne Grant and Jane M. Ussher
    Citation:BMC Cancer 2019 19:570
    Published on: 
  11. Content Type:Research Article

    To evaluate the impact of radiation dose on overall survival (OS) in patients treated with adjuvant chemoradiation (CRT) for pancreatic ductal adenocarcinoma (PDAC).
    Authors:Alessio G. Morganti, Francesco Cellini, Milly Buwenge, Alessandra Arcelli, Sergio Alfieri, Felipe A. Calvo, Riccardo Casadei, Savino Cilla, Francesco Deodato, Giancarmine Di Gioia, Mariacristina Di Marco, Lorenzo Fuccio, Federica Bertini, Alessandra Guido, Joseph M. Herman, Gabriella Macchia…
    Citation:BMC Cancer 2019 19:569
    Published on: 
  12. Content Type:Research Article

    Patients with hepatocellular carcinoma waiting for liver transplantation are commonly treated with locoregional treatments, such as TACE and ablation, to prevent tumor progression and dropout and to improve lo...
    Authors:Malin Sternby Eilard, Mats Andersson, Peter Naredi, Charalampos Geronymakis, Per Lindnér, Christian Cahlin, William Bennet and Magnus Rizell
    Citation:BMC Cancer 2019 19:568
    Published on: 
  13. Content Type:Case Report

    Non-V600E BRAF mutated colorectal cancer (CRC) is a rare disease entity with specific clinical features. These tumors are less likely to have microsatellite instability than CRC with a V600E BRAF mutation and oft...
    Authors:Eduard Callebout, Suzane Moura Ribeiro, Stephanie Laurent, Marc De Man, Liesbeth Ferdinande, Kathleen B. M. Claes, Joni Van der Meulen and Karen P. Geboes
    Citation:BMC Cancer 2019 19:567
    Published on: 
  15. Content Type:Research Article

    Circular RNAs (circRNAs) that form through non-canonical backsplicing events of pre-mRNA transcripts are evolutionarily conserved and abundantly expressed across species. However, the functional relevance of c...
    Authors:Thasni Karedath, Ikhlak Ahmed, Wafa Al Ameri, Fatima M. Al-Dasim, Simeon S. Andrews, Samson Samuel, Iman K. Al-Azwani, Yasmin Ali Mohamoud, Arash Rafii and Joel A. Malek
    Citation:BMC Cancer 2019 19:565
    Published on: 
  16. Content Type:Research Article

    Pre-operative discrimination of malignant from benign adnexal masses is crucial for planning additional imaging, preparation, surgery and postoperative care. This study aimed to define key ultrasound and clini...
    Authors:Maciej Stukan, Michał Badocha and Karol Ratajczak
    Citation:BMC Cancer 2019 19:564
    Published on: 
  17. Content Type:Research Article

    Human papilloma virus (HPV) associated cervical cancer remains a global concern particular, in Sub-Saharan Africa (SSA) where the impact is felt most. Evidence show that many other cancers such as vaginal, ana...
    Authors:Kabelo M. B. Lekoane, Desmond Kuupiel, Tivani P. Mashamba-Thompson and Themba G. Ginindza
    Citation:BMC Cancer 2019 19:563
    Published on: 
  18. Content Type:Case Report

    Cabazitaxel (CBZ) chemotherapy for metastatic castration-resistant prostate cancer (mCRPC) is believed to be palliative because the radiological response rate is low and a durable response is rare. Here, we de...
    Authors:Takeo Kosaka, Hiroshi Hongo and Mototsugu Oya
    Citation:BMC Cancer 2019 19:562
    Published on: 
  19. Content Type:Research Article

    Over-expression of cyclooxygenase (COX)-2 promotes breast cancer progression by multiple mechanisms, including induction of stem-like cells (SLC). Combined gene expression and microRNA microarray analyses of e...
    Authors:Joshua Tordjman, Mousumi Majumder, Mehdi Amiri, Asma Hasan, David Hess and Peeyush K. Lala
    Citation:BMC Cancer 2019 19:561
    Published on: 
  20. Content Type:Research Article

    Hepatocellular carcinoma (HCC) with inferior vena cava (IVC) involvement is a rare disease with poor prognosis. This study aimed to evaluate the outcome of HCC patients receiving radiotherapy (RT) to IVC tumor...
    Authors:Tzu-Hui Pao, Wei-Ting Hsueh, Wei-Lun Chang, Nai-Jung Chiang, Yih-Jyh Lin, Yi-Sheng Liu and Forn-Chia Lin
    Citation:BMC Cancer 2019 19:560
    Published on: 
  21. Content Type:Research Article

    The future of combined immunotherapy (a PD-1/PD-L1 plus a CTLA-4 antagonist) is very bright. However, besides improving efficacy, combined therapy increases treatment-related adverse events (TRAEs). Also, the ...
    Authors:Lihu Gu, Parikshit Asutosh Khadaroo, Hui Su, Liya Kong, Liangliang Chen, Xianfa Wang, Xinlong Li, Hepan Zhu, Xin Zhong, Junhai Pan and Manman Chen
    Citation:BMC Cancer 2019 19:559
    Published on: 
  22. Content Type:Research Article

    Programmed cell death protein-1 (PD-1) and programmed cell death ligand 1 (PD-L1) inhibitors have remarkable clinical efficacy in the treatment of non-small cell lung cancer (NSCLC); however, the breakdown of ...
    Authors:Xiaoying Sun, Raheleh Roudi, Ting Dai, Shangya Chen, Bin Fan, Hongjin Li, Yaqiong Zhou, Min Zhou, Bo Zhu, Chengqian Yin, Bin Li and Xin Li
    Citation:BMC Cancer 2019 19:558
    Published on: 
  23. Content Type:Research Article

    Published genetic risk scores for breast cancer (BC) so far have been based on a relatively small number of markers and are not necessarily using the full potential of large-scale Genome-Wide Association Studi...
    Authors:Kristi Läll, Maarja Lepamets, Marili Palover, Tõnu Esko, Andres Metspalu, Neeme Tõnisson, Peeter Padrik, Reedik Mägi and Krista Fischer
    Citation:BMC Cancer 2019 19:557
    Published on: 
  24. Content Type:Research Article

    The aberrant expression of N-glycolyl GM3 ganglioside (NeuGcGM3) in patients with sarcomas was reevaluated by assessing the relation of this molecule with some clinicopathological features and overall survival...
    Authors:Daniel Pilco-Janeta, Myriam De la Cruz Puebla, Jorge Soriano, Marta Osorio, Iraida Caballero, Adanays Calvo Pérez, Laynes Savon, Natalia Cremades, Rancés Blanco and Adriana Carr
    Citation:BMC Cancer 2019 19:556
    Published on: 
  25. Content Type:Research Article

    Sorting Nexin 27 (SNX27) belongs to a family of sortin nexins and possesses a unique binding domain at the C-terminus which mediates protein-protein interaction in intracellular trafficking, membrane remodelin...
    Authors:Jilei Zhang, Kendy Li, Yongguo Zhang, Rong Lu, Shaoping Wu, Jingrong Tang, Yinglin Xia and Jun Sun
    Citation:BMC Cancer 2019 19:555
    Published on: 
  26. Content Type:Research Article

    The definition of clinical target volume (CTV) in intensity modulated radiation therapy (IMRT) for nasopharyngeal carcinoma (NPC) has not been addressed. We performed this study to assess the feasibility and e...
    Authors:Fang Liu, Ting Luo, Tao Jin, Jiahui Zhang, Zhongzheng Xiang, Ruonan Yan, Li Xie, Xin Wu, Hong Zhang, Feng Wang, Ping Li and Lei Liu
    Citation:BMC Cancer 2019 19:554
    Published on: 
  27. Content Type:Research Article

    Liver function is routinely assessed in clinical practice as liver function tests provide sensitive indicators of hepatocellular injury. However, the prognostic value of enzymes that indicate hepatic injury ha...
    Authors:Ting-Xun Lu, Shuang Wu, Dong-Yan Cai, Ting-Ting Hong, Ying Zhang, Hua-Qiang Gao, Hai-Ying Hua and Xiao-Hong Wu
    Citation:BMC Cancer 2019 19:553
    Published on: 
  28. Content Type:Technical Advance

    Economic evaluations commonly accompany trials of new treatments or interventions; however, regression methods and their corresponding advantages for the analysis of cost-effectiveness data are not widely appr...
    Authors:Jeffrey S. Hoch, Annette Hay, Wanrudee Isaranuwatchai, Kednapa Thavorn, Natasha B. Leighl, Dongsheng Tu, Logan Trenaman, Carolyn S. Dewa, Chris O’Callaghan, Joseph Pater, Derek Jonker, Bingshu E. Chen and Nicole Mittmann
    Citation:BMC Cancer 2019 19:552
    Published on: 
  29. Content Type:Research Article

    Mutated BRCA1/2 genes are associated with hereditary breast and ovarian cancer (HBOC). So far most of the identified BRCA1/2 pathogenic variants are single nucleotide variants (SNVs) or insertions/deletions (Inde...
    Authors:Wen-Ming Cao, Ya-Bing Zheng, Yun Gao, Xiao-Wen Ding, Yan Sun, Yuan Huang, Cai-Jin Lou, Zhi-Wen Pan, Guang Peng and Xiao-Jia Wang
    Citation:BMC Cancer 2019 19:551
    Published on: 
  30. Content Type:Research Article

    To evaluate the value of a three dimension (3D)visualization operative planning system in ultrasound-guided percutaneous microwave ablation (US-PMWA) for large hepatic hemangiomas (LHHs).
    Authors:Xin Li, Chao An, Fangyi Liu, Zhigang Cheng, Zhiyu Han, Xiaoling Yu, Linan Dong, Jie Yu and Ping Liang
    Citation:BMC Cancer 2019 19:550
    Published on: 
  31. Content Type:Research Article

    Breast cancer is a leading cause of cancer-related death in women worldwide. Despite extensive studies in all areas of basic, clinical and applied research, accurate prognosis remains elusive, thus leading to ...
    Authors:Mariana Bustamante Eduardo, Vlad Popovici, Sara Imboden, Stefan Aebi, Nadja Ballabio, Hans Jörg Altermatt, Andreas Günthert and Rolf Jaggi
    Citation:BMC Cancer 2019 19:549
    Published on: 
  32. Content Type:Research Article

    Vascular endothelial growth factor (VEGF), tyrosine kinase (TK) and mechanistic target of rapamycin kinase (mTOR) inhibitors are common first-line (1 L) treatments for metastatic renal cell carcinoma (mRCC). D...
    Authors:Sumanta Pal, Jun Gong, Shivani K. Mhatre, Shih-Wen Lin, Andy Surinach, Sarika Ogale, Rini Vohra, Herschel Wallen and Daniel George
    Citation:BMC Cancer 2019 19:548
    Published on: 
  33. Content Type:Research Article

    Obesity is an important cause of multiple cancer types, amongst which endometrial cancer (EC). The relation between obesity and cancer is complicated and involves alterations in insulin metabolism, response to...
    Authors:Willem Jan van Weelden, Kristine Eldevik Fasmer, Ingvild L. Tangen, Joanna IntHout, Karin Abbink, Antionius E. van Herwaarden, Camilla Krakstad, Leon F. A. G. Massuger, Ingfrid S. Haldorsen and Johanna M. A. Pijnenborg
    Citation:BMC Cancer 2019 19:547
    Published on: 
  34. Content Type:Research Article

    Programmed cell death-1 (PD-1) immune checkpoint inhibitor antibody has proven to be effective in advanced non-small cell lung cancer (NSCLC) patients positive for programmed cell death-1 ligand-1 (PD-L1). How...
    Authors:Akihito Tsunoda, Kei Morikawa, Takeo Inoue, Teruomi Miyazawa, Masahiro Hoshikawa, Masayuki Takagi and Masamichi Mineshita
    Citation:BMC Cancer 2019 19:546
    Published on: 
  35. Content Type:Research Article

    Geospatial technology has facilitated the discovery of disease distributions and etiology and helped target prevention programs. Globally, gastric cancer is the leading infection-associated cancer, and third l...
    Authors:Ricardo L. Dominguez, Charlotte B. Cherry, Dago Estevez-Ordonez, Robertino Mera, Veronica Escamilla, Michael Pawlita, Tim Waterboer, Keith T. Wilson, Richard M. Peek, Gloria Tavera, Scott M. Williams, Margaret L. Gulley, Michael Emch and Douglas R. Morgan
    Citation:BMC Cancer 2019 19:545
    Published on: 
  36. Content Type:Research Article

    The understanding of the molecular biology of pediatric neuronal and mixed neuronal-glial brain tumors is still insufficient due to low frequency and heterogeneity of those lesions which comprise several subty...
    Authors:Magdalena Zakrzewska, Renata Gruszka, Konrad Stawiski, Wojciech Fendler, Joanna Kordacka, Wiesława Grajkowska, Paweł Daszkiewicz, Paweł P. Liberski and Krzysztof Zakrzewski
    Citation:BMC Cancer 2019 19:544
    Published on: 
  38. Content Type:Research Article

    The multi-functional BMCC1 (BCH motif-containing molecule at the carboxyl terminal region 1)/PRUNE2 plays a clear role in suppression of tumor activity. In the patients with neuroblastoma (NB), reduced express...
    Authors:Mohammad Sazzadul Islam, Ryo Takano, Tomoki Yokochi, Jesmin Akter, Yohko Nakamura, Akira Nakagawara and Yasutoshi Tatsumi
    Citation:BMC Cancer 2019 19:542
    Published on: 
  39. Content Type:Research Article

    Triple negative breast cancer (TNBC) is an aggressive and heterogeneous disease. Nomograms predicting outcomes of TNBC are needed for risk management.
    Authors:Yaping Yang, Ying Wang, Heran Deng, Cui Tan, Qian Li, Zhanghai He, Wei Wei, Enxiang Zhou, Qiang Liu and Jieqiong Liu
    Citation:BMC Cancer 2019 19:541
    Published on: 
  40. Content Type:Research Article

    Despite considerable efforts at developing therapeutic vaccines for cancer, clinical translation of preclinical successes has been challenging, largely due to the difficulty of inducing strong and sustained cy...
    Authors:Sean K. Maynard, Jason D. Marshall, Randall S. MacGill, Li Yu, Jennifer A. Cann, Lily I. Cheng, Michael P. McCarthy, Corinne Cayatte and Scott H. Robbins
    Citation:BMC Cancer 2019 19:540
    Published on: 
  41. Content Type:Case Report

    Avelumab is an anti-programmed cell death ligand 1 (PD-L1) antibody approved for treatment of Merkel cell carcinoma (MCC) and locally advanced or metastatic urothelial carcinoma. It shares a similar side effec...
    Authors:Michael A. Cardis, Hong Jiang, Julius Strauss, James L. Gulley and Isaac Brownell
    Citation:BMC Cancer 2019 19:539
    Published on: 
  42. Content Type:Research Article

    Despite recent advances in the treatments of hepatocellular carcinoma (HCC), the prognosis of HCC patients remains controversial. The purpose of this study was to investigate the prognostic performance of pret...
    Authors:Mian-Tao Wu, Su-Yin He, Shu-Lin Chen, Lin-Fang Li, Zheng-Qiang He, Yuan-Ying Zhu, Xia He and Hao Chen
    Citation:BMC Cancer 2019 19:538
    Published on: 
  43. Content Type:Research Article

    Intracranial aneurysms after radiotherapy (RT) have previously been reported. However, the majority of studies were case reports. Therefore, we performed a nationwide study to explore the risk of radiation-ind...
    Authors:Wei-Hsun Yang, Yao-Hsu Yang, Pau-Chung Chen, Ting-Chung Wang, Ko-Jung Chen, Chun-Yu Cheng and Chia-Hsuan Lai
    Citation:BMC Cancer 2019 19:537
    Published on: 
  44. Content Type:Research Article

    Aerobic exercise has been shown to slow tumor progression in rodents and humans, but the mechanisms behind this effect are still unclear. Here we show that aerobic exercise in the form of chronic endurance tra...
    Authors:Amit Hagar, Zemin Wang, Sachiko Koyama, Josua Aponte Serrano, Luma Melo, Stephanie Vargas, Richard Carpenter and John Foley
    Citation:BMC Cancer 2019 19:536
    Published on: 
Publicado por en

No hay comentarios:

Publicar un comentario

Suscribirse a: Enviar comentarios (Atom)