Hereditary Breast and Ovarian Cancer ▲ Public Health Genomics Knowledge Base (v1.2)

Public Health Genomics Knowledge Base (v1.2)

Hereditary Breast and Ovarian Cancer

This week is hereditary breast and ovarian cancer (HBOC) week. For information on HBOC check out our new web pages and CDC BringYourBrave campaign website.

Last Updated: Sep 28, 2016

• Psychosocial outcomes and counselee satisfaction following genetic counseling for hereditary breast and ovarian cancer: A patient-reported outcome study.
  Oberguggenberger Anne et al. Journal of psychosomatic research 2016 Oct 8939-45
• BRCA Share: A Collection of Clinical BRCA Gene Variants.
  Beroud Christophe et al. Human mutation 2016 Sep
• Hereditary breast and ovarian cancer: successful systematic implementation of a group approach to genetic counselling.
  Benusiglio Patrick R et al. Familial cancer 2016 Sep
• Age at menarche and age at natural menopause in East Asian women: a genome-wide association study.
  Shi Jiajun, et al. Age (Dordrecht, Netherlands) 2016 9
• Occult and subsequent cancer incidence following risk-reducing surgery in BRCA mutation carriers.
  Zakhour Mae, et al. Gynecologic oncology 2016 9
• The RAD51C exonic splice-site mutations c.404G>C and c.404G>T are associated with familial breast and ovarian cancer.
  Neidhardt Guido, et al. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 2016 9
• Gene panel sequencing in familial Breast/Ovarian Cancer patients identifies multiple novel mutations also in genes others than BRCA1/2.
  Kraus Cornelia, et al. International journal of cancer 2016 9
• Molecular determination of the clonal relationships between multiple tumors in BRCA1/2-associated breast and/or ovarian cancer patients is clinically relevant.
  Geurts-Giele Willemina R R, et al. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2016 9
• Detection of ATM germline variants by the p53 mitotic centrosomal localization test in BRCA1/2-negative patients with early-onset breast cancer.
  Prodosmo Andrea, et al. Journal of experimental & clinical cancer research : CR 2016 0 (1) 135
• Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus.
  Lawrenson Kate, et al. Nature communications 2016 0 12675
• BRCA testing within the Department of Veterans Affairs: concordance with clinical practice guidelines.
  Chun Danielle S et al. Familial cancer 2016 Sep
• Ready to clone: CNV detection and breakpoint fine-mapping in breast and ovarian cancer susceptibility genes by high-resolution array CGH.
  Hackmann Karl, et al. Breast cancer research and treatment 2016 8
• Association between BHMT gene rs3733890 polymorphism and cancer risk: evidence from a meta-analysis.
  Xu Yue, et al. OncoTargets and therapy 2016 0 5225-33
• High prevalence and predominance of BRCA1 germline mutations in Pakistani triple-negative breast cancer patients.
  Rashid Muhammad Usman, et al. BMC cancer 2016 0 (1) 673
• Implementation of next-generation sequencing for molecular diagnosis of hereditary breast and ovarian cancer highlights its genetic heterogeneity.
  Pinto Pedro, et al. Breast cancer research and treatment 2016 8

• CDC Information (7)
• CDC-Authored Pub (2)

• Human (26)
• Pathogen (0)

• Human (705)
• Pathogen (0)

• Human (159)
• Pathogen (0)

• Guidelines (8)
• Tier Table (3)
• Synthesis (8)

• Huamn (83)
• Pathogen (0)

Relevant Resources

• Cancer Genomics and Epidemiology Navigator (CGEN)
• Genetics and Genomics Competencies Center (G2C2)
• NIH Genetic Testing Registry
• NIH MedGen Database
• Online Mendelian Inheritance in Man (OMIM)
• PharmGKB