lunes, 26 de diciembre de 2016

Precision Medicine: What Does it Mean for Your Health? | Features | CDC

Precision Medicine: What Does it Mean for Your Health? | Features | CDC
Centers for Disease Control and Prevention. CDC twenty four seven. Saving Lives, Protecting People

Precision Medicine: What Does it Mean for Your Health?

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Precision medicine, sometimes called personalized medicine, is an approach for protecting health and treating disease that takes into account a person’s genes, behaviors, and environment. Interventions are tailored to individuals or groups, rather than using a one-size-fits-all approach in which everyone receives the same care. But what does this mean and how can precision medicine protect your health?
You might have heard the term "precision medicine" and wondered how it relates to you. Precision medicine is about finding your unique disease risks and treatments that will work best for you. Here are some ways that a precision medicine approach can protect your health:
  • Using Family Health History: If you have a family health history of certain diseases, you are more likely to get that disease than someone without that family history. Knowing about your family health history can help you and your doctor take steps to prevent disease or find it early. In some cases, your doctor might recommend genetic counseling to help you decide whether to have genetic testing for a disease that runs in your family.
  • Screening for Diseases Before You Get Sick: Currently, all newborns in the United States are screened for certain medical conditions at birth as part of newborn screening. Screening helps doctors find and treat these babies early, often before they get sick. Babies with certain newborn screening conditions need specific treatments, which can include following a special diet or taking medications.
  • Tailoring Prevention: Most common diseases like cancer and heart disease are due to a combination of lifestyle and genetic factors. However, some people have inherited conditions that make them more likely to get a disease, and these people could benefit from targeted interventions. Women with a BRCA1 or BRCA2 mutation are more likely to get breast or ovarian cancer, and men with a BRCA1 or BRCA2 mutation have an increased risk for some cancers as well. People with Lynch syndrome are more likely to get colorectal (colon) cancer. People with familial hypercholesterolemia are more likely to develop heart disease at a younger age and to die from the disease. However, if you have one of these conditions which makes you more likely to get a disease, knowing about it can allow you to take steps to prevent the disease or find it early. These steps can include screening earlier or more often, taking medications, or surgery.
A precision medicine approach can also improve your treatment if you get sick and help public health better track disease:
  • Tailoring Treatments: Certain treatments only work on some people with a disease. For example, ivacaftor, a drug used to treat cystic fibrosis, only works on patients whose cystic fibrosis is due to certain genetic changes. Also, some people have versions of genes (gene variants) that make them more likely to suffer from rare side effects from certain medications. Checking for these gene variants before you take one of these medications can help you avoid medications that could be harmful for you.
  • Finding and Tracking Infectious Diseases: Looking at the DNA of germs can help track disease outbreaks when they occur. Doctors and public health officials can more easily find out which people’s illnesses are caused by the germ. Knowing exactly which germ is making their patient sick can help doctors determine the treatment that will work best. Testing for the germ can also identify affected products, such as specific foods, more easily.

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