herenciageneticayenfermedad: Genetics

jueves, 30 de noviembre de 2017

Genetics - Nov 29, 2017 Edition

	November 29, 2017
	Genetics
	The latest Genetics news from News Medical

	Research findings will help identify genetic causes of brain disorders New findings will help to identify the genetic causes of brain disorders: researchers at the Universities of Basel, Bonn and Cologne have presented a systematic catalog of specific variable locations in the genome that influence gene activity in the human hippocampus, as they report in the journal Nature Communications.

	People with genetic predisposition to later puberty have lower bone mineral density People whose genetic makeup triggers a later-than-average start to puberty have lower bone mineral density, especially in their lower spine. Because adolescence is a critical period for accruing bone, this effect may increase a person's risk of osteoporosis and bone fractures later in life.

			Genetic, ethnic background may be underlying factors for acquired laryngotracheal stenosis Endotracheal intubation, in which a tube is inserted through the voice box (larynx) into the windpipe, and tracheotomy, in which surgery is undertaken to create a hole through the neck and into the windpipe (trachea) to facilitate breathing, are widely used in the hospital setting for elective surgery and in cases of serious illness or critical injury.

			Leishmania genome study reveals the parasites adaptation to the environment A new study, conducted by researchers from the Institut Pasteur in Paris and the Centre for Genomic Regulation (CRG) in Barcelona, have revealed that Leishmania adaptation is a consequence of reversible and frequent chromosomal amplifications.

			Novel discovery connects innate immunity deficiencies to rampant caries in some children Researchers at Umeå University in Sweden have made a novel discovery connecting genetic innate immunity deficiencies to rampant caries and increased risk of dental caries affecting about one in five children.

	New pluripotent stem cell technology provides insights into neuropsychiatric disorders Studying the genetic code allows researchers to know whether some patients with neuropsychiatric disorders either have extra copies of the CHRNA7 gene or are missing copies. However, little was known about the functional consequences of this genetic imbalance in brain cells.

	Leishmania adaptation to environmental changes results from frequent chromosomal amplifications Leishmaniasis is an important human and veterinary disease caused by Leishmania parasites that affect 12 million people in over 98 endemic countries. The disease is now emerging in Europe due to climate change and massive population displacement.

	New approach can track how superbugs travel among and within health care facilities Killer bacteria – ones that have out-evolved our best antibiotics -- may not go away anytime soon. But a new approach to tracking their spread could eventually give us a fighting chance to keep their death toll down.

	3D folding of DNA during cardiomyocyte differentiation provides vital epigenetic mechanisms, study says A new study conducted at the University of Freiburg suggests that three-dimensional (3D) folding of the DNA reorganizes itself during differentiation of pluripotent stem cells to cardiomyocytes.

	Family risk for childhood asthma may involve microbes found in baby's digestive tract A new University of Alberta study shows that the family risk for asthma--typically passed from moms to babies--may not be a result of genetics alone: it may also involve the microbes found in a baby's digestive tract.

	New molecular taxonomy may lead to precision-medicine treatments for hair disorders Two decades ago, oncologists realized that molecular biologists could see medically important differences between tumors that looked identical to pathologists.

	FSU researchers solve puzzle posed by family of rare premature aging disorders New research from Florida State University is beginning to piece together the stubborn puzzle posed by a family of rare and debilitating premature aging disorders.

	Researchers convert natural bacterial immune system into microscopic data recorder Through a few clever molecular hacks, researchers at Columbia University Medical Center have converted a natural bacterial immune system into a microscopic data recorder, laying the groundwork for a new class of technologies that use bacterial cells for everything from disease diagnosis to environmental monitoring.

	UVA researchers developing new tool to help cancer patients make complex care decisions Researchers at the University of Virginia Cancer Center are developing a tool to help patients with prostate cancer better understand the potential risks and rewards of their treatment options. And that tool could ultimately benefit not just those patients but a broad spectrum of patients making complex care decisions based on their tumor's genomic information.

	Flies could act as autonomous bionic drones to help monitor disease outbreaks An international research team led by Nanyang Technological University, Singapore have proposed that swarms of flies can be used to help monitor disease outbreaks.

	Doctors make big money testing urine for drugs, then ignore abnormal results In April 2014, state and federal drug agents raided Jeffrey Campbell's medical clinic in Jeffersonville, Ind. Police cars blocked the parking lot as bewildered patients scattered and the agents carted off boxes of records from the doctor's office.

	Biophotonics in Cell Biology Studies Biophotonics is a branch of science where the interaction between biological substances as well as light is used for probing, manipulating and imaging cells and tissues. This emerging technique is widely used in various fields such as medicine, agriculture, and in studies related to life science and environment.

	Johnson & Johnson Innovation announces CertaDose as winner of latest QuickFire Challenge Johnson & Johnson Innovation LLC today announced developers at CertaDose, Inc. have won its latest QuickFire Challenge: Advancing the Safe Use of Healthcare Products. The challenge called for potentially game-changing, early stage, innovative ideas to help advance the safe use of healthcare products.

	Johns Hopkins researchers crack key part of mystery surrounding proteins What makes the body of a person or any other organism work can, for the most part, be summed up in a word: proteins.

	High levels of natural immune suppressor in leukemia patients linked to poor survival Patients diagnosed with the most common form of leukemia who also have high levels of an enzyme known to suppress the immune system are most likely to die early, researchers say.

	Researchers reveal impact of RNA-binding protein on memory formation process Learning requires the chemical adaptation of individual synapses. Researchers have now revealed the impact of an RNA-binding protein that is intimately involved in this process on learning and memory formation and learning processes.

	Flies carry more disease-causing bacteria than suspected, study reveals A new study, conducted by researchers from the Penn State Eberly College of Science, indicates that the disease-carrying ability of flies could be much greater than previously thought.

	Virus Painting, Lipids and Single Particle Charge Various viral infections still pose a great threat to human and animal health. A wide range of viral species are surrounded by a lipid shell, the envelope, containing viral and cellular proteins.

	Flies may be more potent pathogen carriers than previously thought Flies can be more than pesky picnic crashers, they may be potent pathogen carriers, too, according to an international team of researchers.

	Studies on evolutionary origin of teeth, vertebra illuminate human link to marine organisms Two new studies on the evolutionary origin of teeth and of vertebra further illuminate the human connection to marine organisms that goes back millions of years.

	New study shows how SNO reaction may contribute to Parkinson's disease A new study from The Scripps Research Institute is the first to show precisely how a process in nerve cells called the S-nitrosylation (SNO) reaction- which can be caused by aging, pesticides and pollution- may contribute to Parkinson's disease.

	Mothers of teenagers with ASD report higher levels of negative psychological symptoms Anyone who has ever survived being a teenager should be well aware that parenting a teenager can be no easy feat. But factor in a diagnosis of autism spectrum disorder (ASD) or intellectual disability (ID), and you'll likely have the recipe for a unique set of challenges to the entire family unit.

	Immunologist focuses on initial stages of infection to fight against HIV In a project funded by the Austrian Science Fund FWF, Doris Wilflingseder investigates the initial stages of infection - the time span when the immune system might still stop HIV.

	Birth complications associated with decreased dopamine levels in the brain, study reveals A new study, published in eLife, shows that most people born prematurely, who also suffered small brain injuries during the time of birth, have lower levels of dopamine in the brain.

	Problems at birth linked to long-lasting chemical changes in the brain New King's College London research, published today (28 November) in eLife, shows that adults born prematurely - who also suffered small brain injuries around the time of birth - have lower levels of dopamine in the brain.

	Researchers tackling deadly TB discuss the way forward in treatment and prevention Researchers from across the world who are tacking the deadly bacterial disease tuberculosis (TB) attended a symposium at St George's, University of London to discuss the way forward in treatment and prevention.

	Challenges in Targeted Metabolomics Targeted metabolomics is a quantitative approach of metabolomics as it depends on measuring the known metabolites of specific pathways. Since targeted metabolomics is a continually evolving field, it faces enormous obstacles in its widespread approach.

	Agoraphobia Causes Agoraphobia is a fear of open spaces, or, sometimes, of leaving the home. It is diagnosed when the affected person experiences anxiety symptoms or panic attacks in multiple situations that fall under the umbrella of agoraphobia triggers. The origins of agoraphobia can be complex. They include trauma, alterations in the brain chemistry, and co-occurring disorders.

	Study finds specific tumor environment that stimulates cancer cells to metastasize A new study, conducted by a team of researchers from the University of California, San Diego, has identified how the environment surrounding a tumor can stimulate metastatic behavior in the individual cancer cells. Researchers found that the tumor cells activate a particular set of genes and begin to form blood vessel-like structures when they are confined in a densely packed environment.

	Distinct small differences in the human brain may contribute to our cognitive abilities The most dramatic divergence between humans and other primates can be found in the brain, the primary organ that gives our species its identity.