Breast Cancer - Nov 2, 2017 Edition

November 2, 2017     Breast Cancer     The latest breast cancer news from News Medical

Women can focus on modifiable risk factors to prevent breast cancer   Breast cancer is the most common cancer among American women (except for skin cancers). One in eight women in the United States will develop invasive breast cancer during their lifetime with an estimated 252,710 new cases of invasive breast cancer in 2017.       Researchers investigate how component of soy may suppress breast cancer development   A University of Arizona Cancer Center research team is engaged in a series of studies to investigate how genistein, a component of soy foods, might suppress the development of breast cancer.

Pregnancy does not incur greater risk of relapse for breast cancer survivors   A recent study published in the Journal of the National Cancer Institute indicates that pregnancy does not incur a greater risk of relapse for survivors of breast cancer.         Breast cancer adjuvant treatment discordance linked to general distrust in healthcare system   Nearly one-third of women with breast cancer went against their doctor's advice and chose not to begin or complete the recommended adjuvant anti-cancer therapy to kill residual tumor cells following surgery, according to a study led by a Johns Hopkins Bloomberg School of Public Health researcher.         Majority of women at higher risk for breast cancer decline MRI screenings, study finds   Some women, because of genetic predisposition, personal, or family history, have a higher than average lifetime risk of developing breast cancer. For those women, earlier magnetic resonance imaging (MRI) is recommended for cancer screening.

Researchers show how changes along lining of mammary ducts can lead to breast cancer   Breast cancer researchers have mapped early genetic alterations in normal-looking cells at various distances from primary tumors to show how changes along the lining of mammary ducts can lead to disease.       Regional anesthesia for breast cancer surgery patients associated with better outcomes   Physicians believe that the use of regional anesthesia is associated with lower levels of inflammation and a better immune response in breast cancer surgery patients.       Surveillance rather than surgery can be safe option for women with FEA lesions   The detection of certain non-cancerous "high risk" breast lesions can lead to surgical treatment in women, but one of the largest studies of a specific type of high-risk lesion, flat epithelial atypia (FEA), calls for close observation, rather than surgical removal of these lesions in most cases, according to study results published on the web site of the Journal of the American College of Surgeons in advance of print.       PARP inhibitors may have efficacy in selected TNBC patients outside of germline BRCA mutation   The investigational PARP inhibitor talazoparib caused regression of patient-derived xenografts (PDXs) of triple-negative breast cancers (TNBC) that had BRCA mutations and also those that did not have BRCA mutations but had other alterations in DNA damage-repair pathways.       MUSC and SCSU join forces to address health disparities   Marvella Ford missed out on a fundamental part of childhood: having grandparents to spoil and take care of her. They all died before she was born. "That's a tremendous loss that you can never overcome. I grew up not having met or seen pictures of any of my grandparents," she said.       Understanding obesity-cancer link to develop effective prevention strategies   In 2012, about 28,000 new cases of cancer in men (3.5%) and 72,000 in women (9.5%) were due to overweight or obesity in the United States alone. There is an urgent need for research that focuses on the cancer-promoting effects of obesity as it's the leading preventable cause of cancer for women and the second for men.       Updated guidelines offer support for appropriate, safe use of accelerated partial-breast irradiation   Cleveland Clinic researcher Chirag Shah, M.D., led the development of updated guidelines for the appropriate and safe utilization of accelerated partial-breast irradiation. The guidelines are published online in the journal, Brachytherapy.       Sleeper cells in cancerous tumors can be destroyed if they possess specific defects   In many metastasized types of cancer, disseminated tumors grow back despite successful chemotherapy. As a research team under the direction of the University of Bern, Switzerland, has now discovered, this is because of isolated cancer cells that survive the chemotherapy due to a phase of dormancy.       Newly identified microRNA impedes malignancy of tumor cells and metastasis   Cancer cells can reactivate a cellular process that is an essential part of embryonic development. This allows them to leave the primary tumor, penetrate the surrounding tissue and form metastases in peripheral organs.

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