herenciageneticayenfermedad: Pulmonology - Oct 31, 2017 Edition

Pulmonology
	The latest pulmonology news from News Medical

	Survival of early stage lung cancer patients improves with advancement in surgery, radiation With the advancement of surgical and radiation therapy strategies for stage 1 non-small-cell lung cancer (NSCLC), more patients are being treated, resulting in higher survival rates, according to a study published online today in The Annals of Thoracic Surgery.

	Asthma prevalence and urgent care vary widely among different neighborhoods, research reveals In a new study presented at CHEST 2017, researchers from Columbia University Medical Center in New York aimed to determine if the associations between combustion-related air pollutant levels and urgent asthma care differed by neighborhood in New York City.

	Dartmouth study uncovers three novel genetic biomarkers for lung cancer Both environmental and genetic risk factors contribute to development of lung cancer. Tobacco smoking is the most well-known environmental risk factor associated with lung cancer. A Dartmouth research team led by Yafang Li, PhD, has conducted a study to display that gene-smoking interactions play important roles in the etiology of lung cancer.

			Lung microbiome plays major role in asthma severity and response to treatment While the microbiome has gained significant attention for its impact on digestive health in recent years, its effect on lung disease has largely remained unstudied.

			Risk Factors and Walking Pneumonia Prevention Walking pneumonia is a mild form of pneumonia which is likely to spread fast through a community, since it is easily transmitted. The infection is bacterial in nature and is also known as atypical pneumonia (although the latter term may be used more broadly, as it may encompass pneumonias caused by viruses, fungi and protozoa).

			SU2C and its collaborators announce four teams to intercept cancer at earliest stages Stand Up To Cancer, joined by the Lustgarten Foundation for Pancreatic Cancer Research, LUNGevity, and the American Lung Association, announced today four teams of top researchers who will carry out an attack on cancers of the lung and pancreas using a radical new approach of “interception” of cancers at very early stages, when they can be more successfully treated.

	Eczema and family history linked to severe hospitalization for children with asthma Asthma and allergies are related, and many people who suffer from asthma have allergies that trigger their asthma. Research being presented at the American College of Allergy, Asthma and Immunology's Annual Scientific Meeting examines the relationship between medical history and allergic reactions in children, and how long they stayed in the hospital after an asthma attack.

	Dogs may protect children from allergic eczema and asthma "Good dog!" Two studies being presented at the American College of Allergy, Asthma and Immunology Annual Scientific Meeting show there may be even more reason to love your dog.

	Study offers solution to protect against vaccine-enhanced respiratory disease Researchers have discovered that a virus-like particle vaccine can prime the body's immune response and prevent the severe respiratory disease that results when patients given an early form of a vaccine for respiratory syncytial virus (RSV) are exposed to RSV, according to a study led by Georgia State University.

	Physical, psycho-social interventions in advanced lung cancer patients improve functional capacity Physical exercise and psycho-social interventions in patients with advanced stage lung cancer improved functional capacity, which may be linked to quality of life benefits.

	How is Walking Pneumonia Treated? Pneumonia is a respiratory illness that affects the patient’s ability to breathe easily. The air sacs in the lungs are filled up with fluid or pus when the infection strikes. This can result in symptoms such as fever, a slowly worsening cough, runny or leaky nose, and an overwhelming sense of tiredness. There are more than thirty different causes of pneumonia, resulting in different degrees of severity of the illness.

	Researchers identify predator bacteria in microbiota of cystic fibrosis patients For the first time, researchers have found the presence of predator bacteria in the microbiota of cystic fibrosis patients. There are researchers from Universidad Politécnica de Madrid among the authors of this finding.

	Walking Pneumonia: When to See a Doctor? There is a often a general reluctance to visit the doctor when one falls ill. The departure from routine and taking time off when you can hardly afford it seem like strong disincentives.

	New vaccine for pneumonia holds promise to save thousands of lives In 2004, pneumonia killed more than 2 million children worldwide, according to the World Health Organization. By 2015, the number was less than 1 million.

	Yoga can be beneficial to people with lung cancer and their caregivers In a feasibility trial of people with advanced lung cancer receiving radiation therapy, and their caregivers, yoga was beneficial to both parties. These findings will be presented at the upcoming 2017 Palliative and Supportive Care in Oncology Symposium in San Diego, California.

	Pharmacological stimulation of nicotinic receptor could be strategy to treat lung inflammation It has been amply proven that smoking can cause serious diseases such as emphysema and cancer. A new study, however, shows that pharmacological stimulation of a specific type of nicotinic receptor in cells of the immune system could be a strategy to treat inflammatory lung disease.

	Drexel researchers pinpoint new targets for treating chronic lung disease in premature infants Researchers at Drexel University have revealed that inhibiting the micro-RNA miR-34a significantly reduces bronchopulmonary dysplasia (BPD) in mice.

	Cancer researchers make breakthrough in identifying genetic changes during immunotherapy For some cancer patients, the road to remission and healing can have its share of speed bumps. That's particularly true of patients with non-small cell lung cancer (NSCLC) who develop a secondary, or acquired, resistance to immunotherapy, which initially was effective against their tumors.

	Findings suggest e-cigarettes may be just as bad as traditional cigarettes E-cigarettes appear to trigger unique immune responses as well as the same ones that cigarettes trigger that can lead to lung disease, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

	E-cigarettes may activate distinctive and potentially damaging immune responses, study reveals A new study, published in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine, suggests that e-cigarettes may stimulate distinct immune responses along with the same responses that cigarettes stimulate resulting in lung disease.

	Researchers find rare genetic variants that may help explain longevity in some CF patients Cystic fibrosis is an inherited disorder caused by genetic mutations that disrupt the normal movement of chloride in and out of cells. Among other health problems, cystic fibrosis compromises the lungs' ability to fight infection and breathe efficiently, making it the most lethal genetic disease in the Caucasian population. Patients have an average lifespan of just 30 to 40 years.

	Study unlocks complexities of cell death process that plays key role in health and disease University of Pittsburgh scientists are unlocking the complexities of a recently discovered cell death process that plays a key role in health and disease, and new findings link their discovery to asthma, kidney injury, and brain trauma.

	Study finds underlying causes of racial, ethnic disparities in cancer survival Racial/ethnic disparities in cancer survival in the U.S. are well documented, but the underlying causes are not well understood. To better explain disparities, researchers examined cancer survival by racial/ethnic group for 877,662 patients diagnosed with breast, prostate, colorectal or lung cancer between 2000–2013 using California Cancer Registry data.

	Allergists look for ways to improve ‘webside manner’ How does an allergist communicate effectively with his or her patient when they're not in the same room with the person being examined? The issue of improving "webside" manner – is one topic in a panel discussion on telemedicine during the American College of Allergy, Asthma and Immunology Annual Scientific Meeting.

	Study: Most pediatricians do not tell parents about early peanut introduction to prevent allergy Guidelines to help parents introduce peanut-containing products to infants to prevent peanut allergies aren't being discussed. New research presented at the American College of Allergy, Asthma and Immunology Annual Scientific Meeting shows pediatricians are not only not having the discussion, they're not referring high-risk babies for testing prior to peanut introduction.

	Scientists explore popular pre-heart transplant therapy’s impact on kidney function Scientists, nephrologists and cardiac surgeons from The Feinstein Institute for Medical Research and Northwell Health's Department of Internal Medicine, Cardiology and Cardio-Thoracic Surgery examined the impact of a popular pre-heart transplant therapy on the kidney in a study published today by The Clinical Journal of the American Society of Nephrology.

	UC San Diego researchers develop 3D visualization tool for mapping omics data onto organs University of California San Diego researchers have developed the first 3D spatial visualization tool for mapping "'omics" data onto whole organs.

	Research: Peanut allergy in children has increased 21% since 2010 Parents often worry about peanut allergies because the reaction to peanuts can be very severe. New, late-breaking research being presented at the American College of Allergy, Asthma and Immunology Annual Scientific Meeting suggests that peanut allergy in children has increased 21 percent since 2010, and that nearly 2.5 percent of U.S. children may have an allergy to peanuts.

	Research: 45% of adults with food allergies develop them in adulthood When people think of food allergies, it's mostly in relation to children. New research being presented at the American College of Allergy, Asthma and Immunology Annual Scientific Meeting shows that almost half of all food-allergic adults surveyed reported one or more adult-onset food allergies.

	Performing Spring Tests on Respiratory Devices Bespak is an leader in specialty medical devices for anesthesia and inhaled drug delivery. Each year, the company produces over 450 million complex devices, most of which include inhalers that are used to administer exact metered doses of aerosolized medicine or dry powder to patients suffering from conditions like: chronic obstructive pulmonary disease, asthma, and other related illnesses.

	Primary Ciliary Dyskinesia: Signs and Symptoms Primary ciliary dyskinesia (PCD) is a rare disease of childhood and the original ciliopathy to be identified. It leads to a variety of clinical manifestations, which often lead to a fatal outcome in early life.

	Health scientists uncover gene linked to lung fibrosis Health scientists at the University of Leicester and University of Nottingham have heralded the discovery of a gene associated with lung fibrosis as 'a potential new avenue of treatment for further research into this terrible disease.'

	New report highlights global burden of pollution-related disease and death Pollution is linked to an estimated nine million deaths each year worldwide – equivalent to one in six (16%) of all deaths, according to a major new report in The Lancet.

	One nurse per 4,000 pupils = not the healthiest arrangement During a 15-minute recess, the elementary school students trooped from the playground toward nurse Catherin Crofton's office — one with a bloody nose, a second with a scraped knee and a third with a headache.

	Flu season: UAB experts recommend everyone to receive their yearly influenza vaccine Flu season is here. The contagious respiratory illness caused by viruses that infect the nose, throat and lungs can cause mild to severe illness and at times may lead to death. People of every age -; including people in good health -; are at risk for flu.

	Montmorency tart cherry juice found to help extend sleep time among adults 50 years and older Montmorency tart cherry juice was found to help extend sleep time by 84 minutes among eight study participants, ages 50 and older who suffer from insomnia, according to a new pilot study published in American Journal of Therapeutics.

	Multiple adverse experiences in early childhood linked to poor health in teen, preteen years Adverse experiences in childhood -; such as the death of a parent, growing up in poverty, physical or sexual abuse, or having a parent with a psychiatric illness - have been associated with physical and mental health problems later in life.

	KU Leuven researchers identify new rapid response mechanism against bacterial infections When bacteria enter our body, they kick-start a powerful immune response. But this chain of reactions doesn't fully account for our immediate responses. Researchers at KU Leuven, Belgium, show that so-called ion channels play a key role as 'first responders'.

	New targeted therapies help relieve symptoms of atopic dermatitis If you think only infants suffer from eczema, think again. The uncomfortable, itchy rash that most people relate to babies and young children occurs frequently in adults.

	Pollutant from forest and crop fires induces genetic damage in human lung cells When exposed in a laboratory to pollution levels comparable to those found in the atmosphere of the Amazon region during the forest and crop burning season, human lung cells suffer severe DNA damage and stop dividing. After 72 hours of exposure, over 30% of the cultured cells are dead.

	Nasal Congestion Causes A stuffy nose is also called nasal congestion. It is the result of swelling and inflammation of the nasal mucosa and underlying tissues, along with the blood vessels that network beneath them. They trap excess fluid, thus becoming full and stuffy. In some cases the nasal congestion is accompanied by a nasal discharge.

	Type 3c diabetes commonly mistaken for type 2 diabetes - study According to British researchers, there is a third kind of diabetes that has until now been misdiagnosed as type 2 diabetes. It is termed type 3c diabetes mellitus write the researchers in the November issue of the journal Diabetes Care.

	Study discovers new genetic risk loci linked to children's food allergies What role do genes play in egg, milk, and nut allergies? A study published in Nature Communications, led by the Max Delbrück Center for Molecular Medicine and Charité - Universitätsmedizin Berlin, has found five genetic risk loci that point to the importance of skin and mucous membrane barriers and the immune system in the development of food allergies.

	Report reveals 84% drop in global measles deaths, but disease still kills 90 000 every year In 2016, an estimated 90 000 people died from measles - an 84% drop from more than 550 000 deaths in 2000 - according to a new report published today by leading health organizations. This marks the first time global measles deaths have fallen below 100 000 per year.

	Blood transfusions should be gender matched between donor and recipient An emergency blood transfusion mandates matching of the blood types so that the donor and the recipient are compatible in their blood types. There is no other matching between the blood bag and the recipient – race, ethnicity, religion, gender etc.

	Study examines risk of using liver organs from hepatitis C positive donors Use of liver organs from selected hepatitis C positive donors should be considered due to modest risk of hepatitis C transmission and the availability of safe and effective direct‐acting antiviral therapies, according to research presented this week at The Liver Meeting -; held by the American Association for the Study of Liver Diseases.

	Researchers use nanopore technique to detect biomarkers of disease Adam Hall, Ph.D., isn't kidding when he says the research he does is on a very small scale. But he is understating things more than just a little.