| Almost all cells in the human body have identical DNA sequences, yet there are 200-plus cell types with different sizes, shapes, and chemical compositions. Determining what parts of the genome are read to make protein and which are silenced is orchestrated by proteins called transcription factors. | |
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| Single-cell analysis holds enormous potential to study how individual cells influence disease and respond to treatment, but the lack of cost-effective and user-friendly instrumentation remains challenging. | |
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| Researchers at St. Jude Children's Research Hospital have discovered that a protein critical to a process called liquid-liquid phase separation within the cell undergoes internal changes in conformation that are key to its function. | |
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| The burst of cells forming cartilage is associated with mineralization during the early stages of bone formation, and nanofragments of the cell membranes can act as nucleation sites for amorphous calcium phosphate, as reported in two studies just published in Integrative Biology and ASC Biomaterials Science and Engineering. | |
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