PubMed Clinical Queries

PubMed Clinical Queries





From PubMed Clinical Queries

PubMed Clinical Queries is an utility offered by PubMed to search scientific literature in specific clinical research areas

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• Search PubMed Clinical Queries for "Pcsk9" 

Results: 5 of 871

• Sex-Specific Mechanisms of Resistance Vessel Endothelial Dysfunction Induced by Cardiometabolic Risk Factors.
  Davel AP, Lu Q, Moss ME, Rao S, Anwar IJ, DuPont JJ, Jaffe IZ.J Am Heart Assoc. 2018 Feb 16; 7(4). Epub 2018 Feb 16.
• Alirocumab versus usual lipid-lowering care as add-on to statin therapy in individuals with type 2 diabetes and mixed dyslipidaemia: The ODYSSEY DM-DYSLIPIDEMIA randomized trial.
  Ray KK, Leiter LA, Müller-Wieland D, Cariou B, Colhoun HM, Henry RR, Tinahones FJ, Bujas-Bobanovic M, Domenger C, Letierce A, et al.Diabetes Obes Metab. 2018 Feb 13; . Epub 2018 Feb 13.
• Long-term efficacy and safety of proprotein convertase subtilisin/kexin 9 monoclonal antibodies: A meta-analysis of 11 randomized controlled trials.
  Bai J, Gong LL, Li QF, Wang ZH.J Clin Lipidol. 2018 Jan 12; . Epub 2018 Jan 12.
• PCSK9 inhibition for LDL lowering and beyond - implications for patients with peripheral artery disease.
  Gebauer K, Reinecke H.Vasa. 2018 Feb 7; :1-12. Epub 2018 Feb 7.
• PCSK9 inhibitors: a non-statin cholesterol-lowering treatment option.
  Pokrywka GS.Postgrad Med. 2018 Feb 7; . Epub 2018 Feb 7.

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This column displays citations filtered to a specific clinical study category and scope. These search filters were developed by Haynes RB et al. See more filter information.

Systematic Reviews

Results: 5 of 111

• Long-term efficacy and safety of proprotein convertase subtilisin/kexin 9 monoclonal antibodies: A meta-analysis of 11 randomized controlled trials.
  Bai J, Gong LL, Li QF, Wang ZH.J Clin Lipidol. 2018 Jan 12; . Epub 2018 Jan 12.
• Treatment Preferences in Germany Differ Among Apheresis Patients with Severe Hypercholesterolemia.
  Mühlbacher AC, Sadler A, Dippel FW, Juhnke C.Pharmacoeconomics. 2018 Jan 31; . Epub 2018 Jan 31.
• Effect of the PCSK9-monoclonal antibodies on new-onset diabetes mellitus and glucose metabolism: a systematic review and meta-analysis.
  Cao YX, Liu HH, Dong QT, Li S, Li JJ.Diabetes Obes Metab. 2018 Jan 27; . Epub 2018 Jan 27.
• The systematic review of randomized controlled trials of PCSK9 antibodies challenges their "efficacy breakthrough" and the "lower, the better" theory.
  Battaggia A, Scalisi A, Donzelli A.Curr Med Res Opin. 2018 Jan 25; :1-6. Epub 2018 Jan 25.
• High circulating proprotein convertase subtilisin/Kexin type 9 concentration associates with cardiovascular risk: A meta-analysis of cohort studies.
  Qiu C, Zhou Q, Li X, Zhang Z, Zeng P, Cao Z, Pan B, Li X, Chen AF.Medicine (Baltimore). 2017 Dec; 96(48):e8848.

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This column displays citations for systematic reviews, meta-analyses, reviews of clinical trials, evidence-based medicine, consensus development conferences, and guidelines. See filter information or additional related sources.

Medical Genetics

Topic:AllDiagnosisDifferential DiagnosisClinical DescriptionManagementGenetic CounselingMolecular GeneticsGenetic Testing

Results: 5 of 875

• New Sequencing technologies help revealing unexpected mutations in Autosomal Dominant Hypercholesterolemia.
  Elbitar S, Susan-Resiga D, Ghaleb Y, El Khoury P, Peloso G, Stitziel N, Rabès JP, Carreau V, Hamelin J, Ben-Djoudi-Ouadda A, et al.Sci Rep. 2018 Jan 31; 8(1):1943. Epub 2018 Jan 31.
• Usefulness of the genetic risk score to identify phenocopies in families with familial hypercholesterolemia?
  Ghaleb Y, Elbitar S, El Khoury P, Bruckert E, Carreau V, Carrié A, Moulin P, Di-Filippo M, Charriere S, Iliozer H, et al.Eur J Hum Genet. 2018 Jan 26; . Epub 2018 Jan 26.
• The natural history of phytosterolemia: Observations on its homeostasis.
  Mymin D, Salen G, Triggs-Raine B, Waggoner DJ, Dembinski T, Hatch GM.Atherosclerosis. 2018 Feb; 269:122-128. Epub 2017 Dec 28.
• Genetic spectrum of low density lipoprotein receptor gene variations in South Indian population.
  ArulJothi KN, Suruthi Abirami B, Devi A.Clin Chim Acta. 2018 Mar; 478:28-36. Epub 2017 Dec 19.
• Analysis of publicly available LDLR, APOB, and PCSK9 variants associated with familial hypercholesterolemia: application of ACMG guidelines and implications for familial hypercholesterolemia diagnosis.
  Chora JR, Medeiros AM, Alves AC, Bourbon M.Genet Med. 2017 Oct 26; . Epub 2017 Oct 26.

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This column displays citations pertaining to topics in medical genetics. See more filter information.