Rheumatoid Arthritis
Rheumatoid Arthritis Genomics: Severity & Treatment Response - April 29, 2015
CDC and Related Info
- Rheumatoid arthritis
- Genes reported in relation to arthritis, including genomewide association studies via theHuGE Navigator
Association of HLA-DRB1 haplotypes with rheumatoid arthritis severity, mortality, and treatment response ![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Viatte S et al. JAMA, April 28, 2015
Viatte S et al. JAMA, April 28, 2015
RA treatment response influenced by HLA-DRB1 haplotype
by JC Kelly, Medscape, Apr 28 [by free subscription only]
Genetic architectures of seropositive and seronegative rheumatic diseases.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Kirino Y et al. Nat Rev Rheumatol 2015 Apr 28.
Kirino Y et al. Nat Rev Rheumatol 2015 Apr 28.
Human leukocyte antigen polymorphisms and personalized medicine for rheumatoid arthritis.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Furukawa H et al. J. Hum. Genet. 2015 Apr 23.
Furukawa H et al. J. Hum. Genet. 2015 Apr 23.
Replication of PTPRC as genetic biomarker of response to TNF inhibitors in patients with rheumatoid arthritis.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Ferreiro-Iglesias A et al. Pharmacogenomics J. 2015 Apr 21.
Ferreiro-Iglesias A et al. Pharmacogenomics J. 2015 Apr 21.
A genome-wide association study identifies a new locus associated with the response to anti-TNF therapy in rheumatoid arthritis.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Julià A et al. Pharmacogenomics J. 2015 Apr 21.
Julià A et al. Pharmacogenomics J. 2015 Apr 21.
Genetic variants within the TNFRSF1B gene and susceptibility to rheumatoid arthritis and response to anti-TNF drugs: a multicenter study.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Canet LM et al. Pharmacogenet. Genomics 2015 Apr 4.
Canet LM et al. Pharmacogenet. Genomics 2015 Apr 4.
Variation at FCGR2A and functionally related genes is associated with the response to anti-TNF therapy in rheumatoid arthritis.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Avila-Pedretti G et al. PLoS ONE 2015 (4) e0122088
Avila-Pedretti G et al. PLoS ONE 2015 (4) e0122088
FcGR genetic polymorphisms and the response to adalimumab in patients with rheumatoid arthritis.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Dávila-Fajardo CL et al. Pharmacogenomics 2015 Mar (4) 373-81
Dávila-Fajardo CL et al. Pharmacogenomics 2015 Mar (4) 373-81
Genetic contribution of DKK-1 polymorphisms to RA structural severity and DKK-1 level of expression.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Miceli-Richard C et al. Ann. Rheum. Dis. 2015 Mar 24.
Miceli-Richard C et al. Ann. Rheum. Dis. 2015 Mar 24.
Rheumatoid Arthritis: Recent Genetic Insights - February 5, 2015
To what extent is the familial risk of rheumatoid arthritis explained by established rheumatoid arthritis risk factors?![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Jiang Xia et al. Arthritis & rheumatology (Hoboken, N.J.) 2015 Feb (2) 352-62
Jiang Xia et al. Arthritis & rheumatology (Hoboken, N.J.) 2015 Feb (2) 352-62
Heritability of RA remains unexplained. Established risk factors only provide partial explanation for familial risk of rheumatoid arthritis![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
by Pam Harrison, Medpage Today, Feb 5
by Pam Harrison, Medpage Today, Feb 5
Personalized medicine in rheumatoid arthritis: is the glass half full or half empty.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Huizinga TW. J Intern Med. 2014 Oct 14.
Huizinga TW. J Intern Med. 2014 Oct 14.
The genetics of rheumatoid arthritis: risk and protection in different stages of the evolution of RA.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Yarwood A, et al. Rheumatology (Oxford). 2014 Sep 18
Yarwood A, et al. Rheumatology (Oxford). 2014 Sep 18
Association of susceptible genetic markers and autoantibodies in rheumatoid arthritis.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Mohan VK, et al. J Genet. 2014 Aug;93(2):597-605
Mohan VK, et al. J Genet. 2014 Aug;93(2):597-605
Interleukins and interleukin receptors in rheumatoid arthritis: Research, diagnostics and clinical implications.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Magyari L, et al. World J Orthop. 2014 Sep 18;5(4):516-36.
Magyari L, et al. World J Orthop. 2014 Sep 18;5(4):516-36.
Genetic basis of rheumatoid arthritis: A current review.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Kochi Y, et al. Biochem Biophys Res Commun. 2014 Sep 19;452(2):254-262.
Kochi Y, et al. Biochem Biophys Res Commun. 2014 Sep 19;452(2):254-262.
Early predictors of prognosis in juvenile idiopathic arthritis: a systematic literature review.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
van Dijkhuizen EH, et al. Ann Rheum Dis. 2014 Jun 24.
van Dijkhuizen EH, et al. Ann Rheum Dis. 2014 Jun 24.
Rheumatoid Arthritis: Genetics and Public Health - October 2, 2014
CDC information: Rheumatoid arthritis
Genetics and rheumatoid arthritis,
from the NIH Genetics Home Reference
Check out genetic conditions and tests associated with rheumatoid arthritis,
from the NIH Genetic Testing Registry
Did you know? 861 genes have been reported in relation to rheumatoid arthritis risk and outcomes, including 79 genomewide association studies.
To find out more, visit the HuGE Navigator
Novel risk loci for rheumatoid arthritis in Han Chinese and congruence with risk variants in Europeans.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Jiang L et al. Arthritis Rheumatol. 2014 May;66(5):1121-32.
Jiang L et al. Arthritis Rheumatol. 2014 May;66(5):1121-32.
RADB: a database of rheumatoid arthritis-related polymorphisms![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Zhang R, et al. Database (Oxford) 2014;2014
Zhang R, et al. Database (Oxford) 2014;2014
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