Cancer Genomics
The Cancer Genome Atlas: Accomplishments and Future - April 3, 2015
The Cancer Genome Atlas (TCGA): an immeasurable source of knowledge
Tomczak K, et al. Contemp Oncol (Pozn). 2015; 19(1A): A68-A77.
Tomczak K, et al. Contemp Oncol (Pozn). 2015; 19(1A): A68-A77.
The Cancer Genome Atlas (TCGA) Data Portal
Portal provides a platform for researchers to search, download, and analyze data sets generated by TCGA
Portal provides a platform for researchers to search, download, and analyze data sets generated by TCGA
Cancer Genomics Hub: A resource of the National Cancer Institute, from the USC Genome Browser
Molecular classification of gastric adenocarcinoma: translating new insights from the cancer genome atlas research network.
Sunakawa Y et al. Curr Treat Options Oncol 2015 Apr (4) 331
Sunakawa Y et al. Curr Treat Options Oncol 2015 Apr (4) 331
TCGA data and patient-derived orthotopic xenografts highlight pancreatic cancer-associated angiogenesis.
Gore J et al. Oncotarget 2015 Feb 25.
Gore J et al. Oncotarget 2015 Feb 25.
Radiogenomics of clear cell renal cell carcinoma: preliminary findings of The Cancer Genome Atlas-Renal Cell Carcinoma (TCGA-RCC) Imaging Research Group.
Shinagare AB et al. Abdom Imaging 2015 Mar 10.
Shinagare AB et al. Abdom Imaging 2015 Mar 10.
Proteomics of colorectal cancer in a genomic context: First large-scale mass spectrometry-based analysis from the Cancer Genome Atlas.
Jimenez CR et al. Clin. Chem. 2015 Feb 26.
Jimenez CR et al. Clin. Chem. 2015 Feb 26.
End of cancer-genome project prompts rethink
Geneticists debate whether focus should shift from sequencing genomes to analysing function. Heidi Ledford, Nature News and Comments, January 2015
Geneticists debate whether focus should shift from sequencing genomes to analysing function. Heidi Ledford, Nature News and Comments, January 2015
Cancer Genomics: Insights into Driver Mutations - March 10, 2015
Seek and destroy: Relating cancer drivers to therapies
E. Martinez-Ledesma et al. Cell, March 9, 2015
E. Martinez-Ledesma et al. Cell, March 9, 2015
In silico prescription of anticancer drugs to cohorts of 28 tumor types reveals targeting opportunities
C Rubio-Perez et al. Cancer Cell, March 9, 2015
C Rubio-Perez et al. Cancer Cell, March 9, 2015
MADGiC: a model-based approach for identifying driver genes in cancer. [PDF 373.56 KB]
Keegan D. Korthauer et al. Bioinformatics, January 2015
Keegan D. Korthauer et al. Bioinformatics, January 2015
Identifying driver mutations in sequenced cancer genomes: computational approaches to enable precision medicine.
Benjamin J Raphael et al. Genome Medicine 2014
Benjamin J Raphael et al. Genome Medicine 2014
Novel recurrently mutated genes in African American colon cancers.
Guda K et al. Proc Natl Acad Sci U S A. 2015 Jan 12
Guda K et al. Proc Natl Acad Sci U S A. 2015 Jan 12
Sparse expression bases in cancer reveal tumor drivers.
Logsdon BA, et al. Nucleic Acids Res. 2015 Jan 12
Logsdon BA, et al. Nucleic Acids Res. 2015 Jan 12
Patient-specific driver gene prediction and risk assessment through integrated network analysis of cancer omics profiles.
Bertrand D, et al. Nucleic Acids Res. 2015 Jan 8
Bertrand D, et al. Nucleic Acids Res. 2015 Jan 8
Identification of constrained cancer driver genes based on mutation timing.
Sakoparnig T, et al. PLoS Comput Biol. 2015 Jan 8;11(1):e1004027
Sakoparnig T, et al. PLoS Comput Biol. 2015 Jan 8;11(1):e1004027
CaMoDi: a new method for cancer module discovery.
Manolakos A, et al. BMC Genomics. 2014 Dec 12;15 Suppl 10:S8.
Manolakos A, et al. BMC Genomics. 2014 Dec 12;15 Suppl 10:S8.
VHL, the story of a tumour suppressor gene.
Gossage L, et al. Nat Rev Cancer. 2014 Dec 23;15(1):55-64
Gossage L, et al. Nat Rev Cancer. 2014 Dec 23;15(1):55-64
Targeting the MET pathway for potential treatment of NSCLC.
Li A, et al. Expert Opin Ther Targets. 2014 Dec 23:1-12
Li A, et al. Expert Opin Ther Targets. 2014 Dec 23:1-12
Deciphering oncogenic drivers: from single genes to integrated pathways.
Chen J, et al. Brief Bioinform. 2014 Nov 5.
Chen J, et al. Brief Bioinform. 2014 Nov 5.
Cancer Genomics: Impact of Recent Insights - October 30, 2014
Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin.
Katherine A. Hoadley et al. Cell, August 2014
Katherine A. Hoadley et al. Cell, August 2014
Genome study overhauls cancer categories, shifts from tissues to molecular subtypes, by Kevin Mayer, Genetics Bioengineering News, Aug 8
It's time for us to think about cancer differently, by Paula Mejia, Newsweek, Aug 8
NIH information: What is cancer genomics and the genetic basis of cancer?
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