Obesity
Obesity: New Genomic Insights - March 30, 2015
The Hunger Genes: Pathways to obesity![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
van der Klaauw AA et al. Cell, March 26, 2015
van der Klaauw AA et al. Cell, March 26, 2015
Polymorphisms in endothelin system genes, arsenic levels and obesity risk.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Martínez-Barquero V et al. PLoS ONE 2015 (3) e0118471
Martínez-Barquero V et al. PLoS ONE 2015 (3) e0118471
Contribution of common non-synonymous variants in PCSK1 to body-mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331,175 individuals.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Nead KT et al. Hum. Mol. Genet. 2015 Mar 17.
Nead KT et al. Hum. Mol. Genet. 2015 Mar 17.
Gene-environment interactions and obesity: recent developments and future directions.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Huang T et al. BMC Med Genomics 2015 530
Huang T et al. BMC Med Genomics 2015 530
Genetic studies yield new insights into obesity
by Dr. Francis Collins, NIH Director's Blog, Feb 19
Weighty impact of new genetic fat map ,
by Rebecca Burbridge, PHG Foundation, Feb 13
Genetic studies of body mass index yield new insights for obesity biology.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Locke Adam E et al. Nature 2015 Feb 12. (7538) 197-206
Locke Adam E et al. Nature 2015 Feb 12. (7538) 197-206
New genetic loci link adipose and insulin biology to body fat distribution.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Shungin Dmitry et al. Nature 2015 Feb 12. (7538) 187-96
Shungin Dmitry et al. Nature 2015 Feb 12. (7538) 187-96
Lipid exposure elicits differential responses in gene expression and DNA methylation in primary human skeletal muscle cells from severely obese women.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Maples Jill M et al. Physiol. Genomics 2015 Feb 10.
Maples Jill M et al. Physiol. Genomics 2015 Feb 10.
Associations between TRPV4 genotypes and body mass index in Taiwanese subjects.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Duan De-Min et al. Mol. Genet. Genomics 2015 Feb 3.
Duan De-Min et al. Mol. Genet. Genomics 2015 Feb 3.
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Wessel Jennifer et al. Nat Commun 2015 5897
Wessel Jennifer et al. Nat Commun 2015 5897
Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Mahajan Anubha et al. PLoS Genet. 2015 Jan (1) e1004876
Mahajan Anubha et al. PLoS Genet. 2015 Jan (1) e1004876
Obesity breakthrough: Researchers identify new genetic markers for obesity in largest-ever genomic study on the disease,
International Business Times, Feb 11
Obesity: Recent Public Health and Genomic Insights- January 8, 2015
Life years lost and lifetime healthcare expenditures associated with diabetes in the U.S., National Health Interview Survey, 1997-2000.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Leung MM, et al. Diabetes Care. 2014 Dec 31.
Cohort of birth modifies the association between FTO genotype and BMI.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
James Niels Rosenquist, et al. PNAS, December 2014
Leung MM, et al. Diabetes Care. 2014 Dec 31.
Cohort of birth modifies the association between FTO genotype and BMI.
James Niels Rosenquist, et al. PNAS, December 2014
Gene linked to obesity hasn’t always been a problem, study finds,
New York Times, Dec 31, 2014
FTO and obesity: mechanisms of association.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Zhao X, et al. Curr Diab Rep. 2014;14(5):486
Zhao X, et al. Curr Diab Rep. 2014;14(5):486
Nutritional genomics and metabolomics in obesity and type 2 diabetes.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Frank B Hu et al. BMC Genomics 2014, 15(Suppl 2):O10
Frank B Hu et al. BMC Genomics 2014, 15(Suppl 2):O10
Advances in exercise, fitness, and performance genomics in 2013.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Wolfarth B, et al. Med Sci Sports Exerc. 2014;46(5):851-9
Wolfarth B, et al. Med Sci Sports Exerc. 2014;46(5):851-9
Genetic susceptibility to type 2 diabetes and obesity: follow-up of findings from genome-wide association studies.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Basile KJ, et al. Int J Endocrinol. 2014;2014:769671
Basile KJ, et al. Int J Endocrinol. 2014;2014:769671
Obesity: Genes, Environment & Public Health - September 11, 2014
CDC media advisory: New CDC state obesity map now available, Sep 4
CDC information: Obesity prevalence in 2013 varies across states and regions
CDC information: Genomics and health- Behavior, environment, and genetic factors all have a role in causing people to be overweight and obese
Did you know? More than 1660 genes have been reported in relation to obesity occurrence and outcomes including 178 genomewide association studies? To find out more, visit the HuGE Navigator![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_v3cIWXmdKNZcprEpZcaRt3r76_tygEW3QcbjbyD96VNB-BWM-jt6903EobvLmlakeCVbdPZqCtYhroAj5NPxafr5LZh4Iv84T2UT3ZbfaaCDhYoJeNeqjC=s0-d)
Genes are not destiny. Obesity-promoting genes in an obesity-promoting world,
Harvard School of Public Health
It's not all in the genes,
Tim Caulfield, Policy Options, Jul 2014
The application of public health genomics to the prevention and management of obesity in the UK,
PHG Foundation (2013)
Ancient famine-fighting genes can't explain obesity. Scientists look beyond calorie-hoarding genes to understand widening waistlines,
by Laura Beil, Science News, Sep 5
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