Lung cancer

Public Health Genomics Knowledge Base (v1.2)




Last Updated: Oct 21, 2016

• A randomized Phase II study of veliparib with temozolomide or carboplatin/paclitaxel versus placebo with carboplatin/paclitaxel in BRCA1/2 metastatic breast cancer: design and rationale.
  Isakoff Steven J, et al. Future oncology (London, England) 2016 10
• The prevalence of EGFR mutation in patients with non-small cell lung cancer: a systematic review and meta-analysis.
  Zhang Yue-Lun, et al. Oncotarget 2016 10
• Advanced cancer patients' attitudes towards, and experiences with, screening for somatic mutations in tumours: a qualitative study.
  Liang R et al. European journal of cancer care 2016 Oct
• Clinically Viable Gene Expression Assays with Potential for Predicting Benefit from MEK Inhibitors.
  Brant Roz G, et al. Clinical cancer research : an official journal of the American Association for Cancer Research 2016 10
• Pembrolizumab versus Chemotherapy for PD-L1-Positive Non-Small-Cell Lung Cancer.
  Reck Martin, et al. The New England journal of medicine 2016 10
• The rs767649 polymorphism in the promoter of miR-155 contributes to the decreased risk for cervical cancer in a Chinese population.
  Wang Shizhi, et al. Gene 2016 10
• Divide and Conquer to Treat Lung Cancer.
  Johnson Bruce E et al. The New England journal of medicine 2016 Oct
• New and emerging targeted treatments in advanced non-small-cell lung cancer.
  Hirsch Fred R et al. Lancet (London, England) 2016 Sep 388(10048) 1012-24
• A Novel Genetic Variant in Long Non-coding RNA Gene NEXN-AS1 is Associated with Risk of Lung Cancer.
  Yuan Hua, et al. Scientific reports 2016 10 34234
• Association and multiple interaction analysis among five XRCC1 polymorphic variants in modulating lung cancer risk in North Indian population.
  Singh Amrita, et al. DNA repair 2016 9
• Development of a RNA-Seq Based Prognostic Signature in Lung Adenocarcinoma.
  Shukla Sudhanshu, et al. Journal of the National Cancer Institute 2017 1 (1)
• The Different Effect of VEGF Polymorphisms on the Prognosis of Non-Small Cell Lung Cancer according to Tumor Histology.
  Lee Soyeon, et al. Journal of Korean medical science 2016 11 (11) 1735-1741
• Role of GSTM1, GSTT1, and GSTP1 IIe105Val gene polymorphisms in the response to chemotherapy and overall survival of advanced non-small cell lung cancer.
  Jia W, et al. Genetics and molecular research : GMR 2016 9 (3)
• Two novel susceptibility loci for non-small cell lung cancer map to low-density lipoprotein receptor-related protein 5.
  Wang Ying, et al. Oncology letters 2016 10 (4) 2307-2318
• Challenges in molecular testing in non-small-cell lung cancer patients with advanced disease.
  Hiley Crispin T et al. Lancet (London, England) 2016 Sep (10048) 1002-11

• CDC Information (2)
• CDC-Authored Pub (8)

• Human (33)
• Pathogen (0)

• Human (3986)
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• Human (65)
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• Guidelines (8)
• Tier Table (4)
• Synthesis (11)

• Huamn (4)
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Relevant Resources

• Cancer Genomics and Epidemiology Navigator (CGEN)
• Genetics and Genomics Competencies Center (G2C2)
• NIH Genetic Testing Registry
• NIH MedGen Database
• Online Mendelian Inheritance in Man (OMIM)
• PharmGKB