Colorectal Cancer
Genomic Tests in Management of Colorectal Cancer - April 2, 2015
CDC Info
- Check out the CDC evidence table on tiered classification of genomic tests for colorectal cancer
- Genetic testing for hereditary colorectal cancer
- March is Colorectal Cancer Awareness
- Screen for Life: National Colorectal Cancer Action Campaign
- Colorectal Cancer Awareness
- Listen to a CDC podcast about genetic testing for Lynch syndrome
- Colorectal cancer screening tests
Costs and effectiveness of genomic testing in the management of colorectal cancer.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sTOQXSz98DkiVr599EHle6XoRFsNJKsms-6eK7JZXK2xMEh4thMlRSTLMSBlaucQCBeW87KGynLIASkyNRbuxjTv3aussFzSE6feLWtJAJ_GJDNzJ-NJ1W=s0-d)
Goldstein DA et al.Oncology (Williston Park, N.Y.) 2015 Mar 15. (3)
Goldstein DA et al.Oncology (Williston Park, N.Y.) 2015 Mar 15. (3)
Cost-effectiveness of genomic testing for colorectal cancer: Are we there yet?![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sTOQXSz98DkiVr599EHle6XoRFsNJKsms-6eK7JZXK2xMEh4thMlRSTLMSBlaucQCBeW87KGynLIASkyNRbuxjTv3aussFzSE6feLWtJAJ_GJDNzJ-NJ1W=s0-d)
Barzi A et al. Oncology, March 2015
Barzi A et al. Oncology, March 2015
Aspirin: Genetics and Colorectal Cancer Risk - March 24, 2015
Precision medicine: Who benefits from Aspirin to prevent colorectal cancer?
Francis Collins, NIH Director, Mar 24
Association of Aspirin and NSAID use with risk of colorectal cancer according to genetic variants.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sTOQXSz98DkiVr599EHle6XoRFsNJKsms-6eK7JZXK2xMEh4thMlRSTLMSBlaucQCBeW87KGynLIASkyNRbuxjTv3aussFzSE6feLWtJAJ_GJDNzJ-NJ1W=s0-d)
Nan H et al. JAMA 2015 Mar 17. (11) 1133-42
Nan H et al. JAMA 2015 Mar 17. (11) 1133-42
Aspirin and NSAID chemoprevention, gene-environment interactions, and risk of colorectal cancer.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sTOQXSz98DkiVr599EHle6XoRFsNJKsms-6eK7JZXK2xMEh4thMlRSTLMSBlaucQCBeW87KGynLIASkyNRbuxjTv3aussFzSE6feLWtJAJ_GJDNzJ-NJ1W=s0-d)
Wender RC et al. JAMA 2015 Mar 17. (11) 1111-2
Wender RC et al. JAMA 2015 Mar 17. (11) 1111-2
Can Aspirin and cancer prevention be ageless companions?![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sTOQXSz98DkiVr599EHle6XoRFsNJKsms-6eK7JZXK2xMEh4thMlRSTLMSBlaucQCBeW87KGynLIASkyNRbuxjTv3aussFzSE6feLWtJAJ_GJDNzJ-NJ1W=s0-d)
Farag M et al. J Clin Diagn Res 2015 Jan (1) XE01-XE03
Farag M et al. J Clin Diagn Res 2015 Jan (1) XE01-XE03
P342. Meta-analysis: Does aspirin or non-aspirin non-steroidal anti-inflammatory drug use reduce colorectal cancer risk in patients with inflammatory bowel disease?![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sTOQXSz98DkiVr599EHle6XoRFsNJKsms-6eK7JZXK2xMEh4thMlRSTLMSBlaucQCBeW87KGynLIASkyNRbuxjTv3aussFzSE6feLWtJAJ_GJDNzJ-NJ1W=s0-d)
J Crohns Colitis 2015 Feb S250
J Crohns Colitis 2015 Feb S250
Impact of regular aspirin use on overall and cancer-specific survival in patients with colorectal cancer harboring a PIK3CA mutation.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sTOQXSz98DkiVr599EHle6XoRFsNJKsms-6eK7JZXK2xMEh4thMlRSTLMSBlaucQCBeW87KGynLIASkyNRbuxjTv3aussFzSE6feLWtJAJ_GJDNzJ-NJ1W=s0-d)
Kothari N et al. Acta Oncol 2015 Apr (4) 487-92
Kothari N et al. Acta Oncol 2015 Apr (4) 487-92
Molecular pathways: Aspirin and Wnt signaling-A molecularly targeted approach to cancer prevention and treatment.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sTOQXSz98DkiVr599EHle6XoRFsNJKsms-6eK7JZXK2xMEh4thMlRSTLMSBlaucQCBeW87KGynLIASkyNRbuxjTv3aussFzSE6feLWtJAJ_GJDNzJ-NJ1W=s0-d)
Gala MK et al. Clin. Cancer Res. 2014 Dec 11.
Gala MK et al. Clin. Cancer Res. 2014 Dec 11.
Gene-environment interaction involving recently identified colorectal cancer susceptibility Loci.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sTOQXSz98DkiVr599EHle6XoRFsNJKsms-6eK7JZXK2xMEh4thMlRSTLMSBlaucQCBeW87KGynLIASkyNRbuxjTv3aussFzSE6feLWtJAJ_GJDNzJ-NJ1W=s0-d)
Kantor D et al. Cancer Epidemiol. Biomarkers Prev. 2014 Sep (9) 1824-33
Kantor D et al. Cancer Epidemiol. Biomarkers Prev. 2014 Sep (9) 1824-33
Modulation of age- and cancer-associated DNA methylation change in the healthy colon by aspirin and lifestyle.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sTOQXSz98DkiVr599EHle6XoRFsNJKsms-6eK7JZXK2xMEh4thMlRSTLMSBlaucQCBeW87KGynLIASkyNRbuxjTv3aussFzSE6feLWtJAJ_GJDNzJ-NJ1W=s0-d)
Noreen F et al. J. Natl. Cancer Inst. 2014 Jul (7)
Noreen F et al. J. Natl. Cancer Inst. 2014 Jul (7)
Aspirin and the risk of colorectal cancer in relation to the expression of 15-hydroxyprostaglandin dehydrogenase (HPGD).![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sTOQXSz98DkiVr599EHle6XoRFsNJKsms-6eK7JZXK2xMEh4thMlRSTLMSBlaucQCBeW87KGynLIASkyNRbuxjTv3aussFzSE6feLWtJAJ_GJDNzJ-NJ1W=s0-d)
Fink SP et al. Sci Transl Med 2014 Apr 23. (233) 233re2
Fink SP et al. Sci Transl Med 2014 Apr 23. (233) 233re2
Expression of HLA class I antigen, aspirin use, and survival after a diagnosis of colon cancer.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sTOQXSz98DkiVr599EHle6XoRFsNJKsms-6eK7JZXK2xMEh4thMlRSTLMSBlaucQCBeW87KGynLIASkyNRbuxjTv3aussFzSE6feLWtJAJ_GJDNzJ-NJ1W=s0-d)
Reimers MS et al. JAMA Intern Med 2014 May (5) 732-9
Reimers MS et al. JAMA Intern Med 2014 May (5) 732-9
Genetic variation in UGT genes modify the associations of NSAIDs with risk of colorectal cancer: colon cancer family registry.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sTOQXSz98DkiVr599EHle6XoRFsNJKsms-6eK7JZXK2xMEh4thMlRSTLMSBlaucQCBeW87KGynLIASkyNRbuxjTv3aussFzSE6feLWtJAJ_GJDNzJ-NJ1W=s0-d)
Scherer D et al. Genes Chromosomes Cancer 2014 Jul (7) 568-78
Scherer D et al. Genes Chromosomes Cancer 2014 Jul (7) 568-78
March is Colorectal Cancer Awareness Month - March 5, 2015
CDC information: Genetic testing for hereditary colorectal cancer
CDC information: Colorectal Cancer Awareness
CDC genomics and health information: Colorectal Cancer Awareness
Colorectal Cancer Screening & Prediction: Recent Genomic Insights - February 20, 2015
Role of tumour molecular and pathology features to estimate colorectal cancer risk for first-degree relatives.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sTOQXSz98DkiVr599EHle6XoRFsNJKsms-6eK7JZXK2xMEh4thMlRSTLMSBlaucQCBeW87KGynLIASkyNRbuxjTv3aussFzSE6feLWtJAJ_GJDNzJ-NJ1W=s0-d)
Win Aung Ko et al. Gut 2015 Jan (1) 101-10
Win Aung Ko et al. Gut 2015 Jan (1) 101-10
Awareness and uptake of family screening in patients diagnosed with colorectal cancer at a young age.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sTOQXSz98DkiVr599EHle6XoRFsNJKsms-6eK7JZXK2xMEh4thMlRSTLMSBlaucQCBeW87KGynLIASkyNRbuxjTv3aussFzSE6feLWtJAJ_GJDNzJ-NJ1W=s0-d)
Hogan Niamh M et al. Gastroenterol Res Pract 2015 194931
Hogan Niamh M et al. Gastroenterol Res Pract 2015 194931
A candidate gene study of capecitabine-related toxicity in colorectal cancer identifies new toxicity variants at DPYD and a putative role for ENOSF1 rather than TYMS.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sTOQXSz98DkiVr599EHle6XoRFsNJKsms-6eK7JZXK2xMEh4thMlRSTLMSBlaucQCBeW87KGynLIASkyNRbuxjTv3aussFzSE6feLWtJAJ_GJDNzJ-NJ1W=s0-d)
Rosmarin Dan et al. Gut 2015 Jan (1) 111-20
Rosmarin Dan et al. Gut 2015 Jan (1) 111-20
Applicability of next generation sequencing technology in microsatellite instability testing.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sTOQXSz98DkiVr599EHle6XoRFsNJKsms-6eK7JZXK2xMEh4thMlRSTLMSBlaucQCBeW87KGynLIASkyNRbuxjTv3aussFzSE6feLWtJAJ_GJDNzJ-NJ1W=s0-d)
Gan Chun et al. Genes (Basel) 2015 (1) 46-59
Gan Chun et al. Genes (Basel) 2015 (1) 46-59
A model to determine colorectal cancer risk using common genetic susceptibility loci.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sTOQXSz98DkiVr599EHle6XoRFsNJKsms-6eK7JZXK2xMEh4thMlRSTLMSBlaucQCBeW87KGynLIASkyNRbuxjTv3aussFzSE6feLWtJAJ_GJDNzJ-NJ1W=s0-d)
Hsu Li et al. Gastroenterology 2015 Feb 12.
Hsu Li et al. Gastroenterology 2015 Feb 12.
The impact of stratifying by family history in colorectal cancer screening programs.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sTOQXSz98DkiVr599EHle6XoRFsNJKsms-6eK7JZXK2xMEh4thMlRSTLMSBlaucQCBeW87KGynLIASkyNRbuxjTv3aussFzSE6feLWtJAJ_GJDNzJ-NJ1W=s0-d)
Goede S Lucas et al. Int. J. Cancer 2015 Feb 6.
Goede S Lucas et al. Int. J. Cancer 2015 Feb 6.
Preliminary validation of a consumer-oriented colorectal cancer risk assessment tool compatible with the US Surgeon General's My Family Health Portrait.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sTOQXSz98DkiVr599EHle6XoRFsNJKsms-6eK7JZXK2xMEh4thMlRSTLMSBlaucQCBeW87KGynLIASkyNRbuxjTv3aussFzSE6feLWtJAJ_GJDNzJ-NJ1W=s0-d)
Feero WG, et al. Genet Med. 2014 Dec 18
Feero WG, et al. Genet Med. 2014 Dec 18
Potential of fecal microbiota for early‐stage detection of colorectal cancer.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sTOQXSz98DkiVr599EHle6XoRFsNJKsms-6eK7JZXK2xMEh4thMlRSTLMSBlaucQCBeW87KGynLIASkyNRbuxjTv3aussFzSE6feLWtJAJ_GJDNzJ-NJ1W=s0-d)
Georg Zeller, et al. Molecular Systems Biology(2014)10:766
Georg Zeller, et al. Molecular Systems Biology(2014)10:766
Valuations of genetic test information for treatable conditions: the case of colorectal cancer screening![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sTOQXSz98DkiVr599EHle6XoRFsNJKsms-6eK7JZXK2xMEh4thMlRSTLMSBlaucQCBeW87KGynLIASkyNRbuxjTv3aussFzSE6feLWtJAJ_GJDNzJ-NJ1W=s0-d)
Kilambi V, et al. Value Health 2014 Dec;17(8):838-45
Kilambi V, et al. Value Health 2014 Dec;17(8):838-45
Clinical potential role of circulating microRNAs in early diagnosis of colorectal cancer patients.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sTOQXSz98DkiVr599EHle6XoRFsNJKsms-6eK7JZXK2xMEh4thMlRSTLMSBlaucQCBeW87KGynLIASkyNRbuxjTv3aussFzSE6feLWtJAJ_GJDNzJ-NJ1W=s0-d)
Du M, et al. Carcinogenesis. 2014 Dec;35(12):2723-30.
Du M, et al. Carcinogenesis. 2014 Dec;35(12):2723-30.
Colorectal Cancer Screening: Stool DNA Screening Test - August 21, 2014
CDC information: Colorectal cancer screening tests
Multitarget stool DNA testing for colorectal-cancer screening![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sTOQXSz98DkiVr599EHle6XoRFsNJKsms-6eK7JZXK2xMEh4thMlRSTLMSBlaucQCBeW87KGynLIASkyNRbuxjTv3aussFzSE6feLWtJAJ_GJDNzJ-NJ1W=s0-d)
Imperiale T, et al. New England Journal of Medicine Mar 2014
Imperiale T, et al. New England Journal of Medicine Mar 2014
Public stated preferences and predicted uptake for genome-based colorectal cancer screening![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sTOQXSz98DkiVr599EHle6XoRFsNJKsms-6eK7JZXK2xMEh4thMlRSTLMSBlaucQCBeW87KGynLIASkyNRbuxjTv3aussFzSE6feLWtJAJ_GJDNzJ-NJ1W=s0-d)
Groothuis-Oudshoorn CG, et al. BMC Med Inform Decis Mak 2014 Mar;14(1):18
Groothuis-Oudshoorn CG, et al. BMC Med Inform Decis Mak 2014 Mar;14(1):18
Stool DNA and colorectal-cancer screening
editorial
Robertson D, et al. New England Journal of Medicine Mar 19
Robertson D, et al. New England Journal of Medicine Mar 19
Colorectal cancer screening: will non-invasive procedures triumph?![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sTOQXSz98DkiVr599EHle6XoRFsNJKsms-6eK7JZXK2xMEh4thMlRSTLMSBlaucQCBeW87KGynLIASkyNRbuxjTv3aussFzSE6feLWtJAJ_GJDNzJ-NJ1W=s0-d)
Timothy Church. Genome Medicine, June 2014
Timothy Church. Genome Medicine, June 2014
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