BRCA1 and BRCA2 genes UPDATE: July 28 - August 4, 2016 || Public Health Genomics Knowledge Base (v1.0)

July 28 - August 4, 2016 

Last Updated: Jul 29, 2016

• International cancer genetics researchers meeting in Israel say half of people who would benefit from testing aren’t candidates under current rules
  Israel 21c, July 28, 2016
• What Men Should Know About BRCA Variant Testing
  M Jacobs, University of Michigan, July 22, 2016
• First application of next-generation sequencing in Moroccan breast/ovarian cancer families and report of a novel frameshift mutation of the BRCA1 gene.
  Jouali Farah, et al. Oncology letters 2016 8 (2) 1192-1196
• The Activities and Impact of State Programs to Address Hereditary Breast and Ovarian Cancer, 2011–2014
  Disease: Breast Cancer|Ovarian Cancer; Type: Multipe Types; State: Georgia|Michigan|Oregon
• Comparison of effectiveness of treatment of patients with sporadic and germline BRCA1-related ovarian cancer.
  Szatkowski Wiktor, et al. Ginekologia polska 2016 0 (6) 422-5
• Implementing rapid, robust, cost-effective, patient-centred, routine genetic testing in ovarian cancer patients.
  George Angela et al. Scientific reports 2016 629506
• Changes of Socio-demographic data of clients seeking genetic counseling for hereditary breast and ovarian cancer due to the "Angelina Jolie Effect".
  Staudigl Christine et al. BMC cancer 2016 16436
• Long-term survival and BRCA status in male breast cancer: a retrospective single-center analysis.
  Gargiulo Piera, et al. BMC cancer 2016 0 (1) 375
• Drawing the Line in Risk-Reducing Gynecologic Surgery in Women With a BRCA Mutation.
  Leath Charles A et al. JAMA oncology 2016 Jun
• Uterine Cancer After Risk-Reducing Salpingo-oophorectomy Without Hysterectomy in Women With BRCA Mutations.
  Shu Catherine A et al. JAMA oncology 2016 Jun
• Contralateral Prophylactic Mastectomy for Women with T4 Locally Advanced Breast Cancer.
  Murphy Brittany L, et al. Annals of surgical oncology 2016 6
• Ovarian cancer in BRCA1 and BRCA2 gene mutation carriers: analysis of prognostic factors and survival.
  Biglia Nicoletta, et al. Ecancermedicalscience 2016 0 639
• Drawing the Line in Risk-Reducing Gynecologic Surgery in Women With a BRCA Mutation
  CA Leath et al, JAMA Oncology, July 1, 2016
• Uterine Cancer After Risk-Reducing Salpingo-oophorectomy Without Hysterectomy in Women With BRCA Mutations
  CA Shu et al, JAMA Oncology, July 1, 2016
• Impact that Timing of Genetic Mutation Diagnosis has on Surgical Decision Making and Outcome for BRCA1/BRCA2 Mutation Carriers with Breast Cancer.
  Chiba Akiko et al. Annals of surgical oncology 2016 Jun

• CDC Information (4)
• CDC-Authored Pub (2)

• Human (40)
• Pathogen (0)

• Human (469)
• Pathogen (0)

• Human (133)
• Pathogen (0)

• Guidelines (7)
• Tier Table (3)
• Synthesis (7)

• Huamn (27)
• Pathogen (0)

Relevant Resources

• Cancer Genomics and Epidemiology Navigator (CGEN)
• Genetics and Genomics Competencies Center (G2C2)
• NIH Genetic Testing Registry
• NIH MedGen Database
• Online Mendelian Inheritance in Man (OMIM)
• PharmGKB

Public Health Genomics Knowledge Base (v1.0)