LO ÚLTIMO EN ALZHEIMER ► Genomics|Features|Alzheimer [idioma inglés únicamente]

Genomics|Features|Alzheimer

Alzheimer's Disease

CDC Info

• Alzheimer's Disease
• September is World Alzheimer's Month
• FastStats on Alzheimer's Disease
• Caregiving for Alzheimer’s Disease
• Podcasts on Alzheimer Disease

Alzheimer's Disease: Recent Genomic Insights - December 4, 2014

A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death. 
Monica K Wetzel-Smith et al. Nature Medicine, November 24, 2014

Genetics of Alzheimer's disease.
Chouraki V, Seshadri S. Adv Genet. 2014;87:245-94.

Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research.
O'Bryant SE et al. Alzheimers Dement. 2014 Sep 27. pii: S1552-5260(14)02765-4.

Alzheimer's test detects disease decade ahead of onset, by Megan Scudellari, Bloomberg News, Nov 17

New blood-based Alzheimer's biomarker panel uses exosomal miRNA, by Madeleine Johnson, GenomeWeb, Nov 21 [by free subscription only]

Alzheimer's Disease Awareness: Genetics & Family History - September 25, 2014

CDC information: September is World Alzheimer's Month- Risk factors for Alzheimer's disease include genetics

CDC report: 2013-2018 Road Map- The Healthy Brain Initiative

Alzheimer's disease genetics fact sheet, from the National Institute on Aging

Did you know? 1621 genes have been reported in relation to risk or outcomes of Alzheimer's disease, including 155 genomewide association studies? ApoE is the most commonly reported gene. To find out more, visit the HuGE Navigator

Find out what genetic conditions and tests are associated with Alzheimer's disease, NIH Genetic Testing Registry

Is Alzheimer's disease genetic? WebMD, July 2014 

Alzheimer's genes: Are you at risk? Several genes have been associated with Alzheimer's disease, but more research is needed, Mayo Clinic

Alzforum

Alzheimer's Disease & Genetics: Recent Insights - August 21, 2014

CDC information: Facts about Alzheimer's disease

CDC report: 2013-2018 Road Map- The Healthy Brain Initiative

Did you know? 1615 genes have beern reported in relation to risk our outcomes of Alzheimer's disease, including 149 genomewide association studies? ApoE is the most commonly reported gene. To find out more, visit the HuGE Navigator

Find out what genetic conditions and tests are associated with Alzheimer's disease, NIH Genetic Testing Registry

Recent Insights

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy. 
Chia-Chen Liu et al.  Nature Reviews Neurology 9, 106-118 (February 2013)

Is apolipoprotein E required for cognitive function in humans?  Implications for Alzheimer drug development
Courtney Lane-Donovan et al. JAMA Neurology, August 11, 2014

Delete ApoE gene, set back Alzheimer's, and preserve brain health? GEN News Highlights, Aug 12

Effects of the absence of apolipoprotein E on lipoproteins, neurocognitive function, and retinal function. 
Mak AC et al, JAMA Neurol. 2014 Aug 11. 

Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease. 
Katie Lunnon et al. Nature Neuroscience, August 18, 2014

Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.