HIV/AIDS
HIV/AIDS: Recent Genomic Insights - December 4, 2014
CDC Vital Signs: HIV care saves lives. Viral suppression is key, November 2014
Recent Advances
Review: influence of ART on HIV genetics.
Simonetti FR, et al. Curr Opin HIV AIDS. 2014 Nov 11.
Simonetti FR, et al. Curr Opin HIV AIDS. 2014 Nov 11.
RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Hu W, et al. PNAS, Jul 21, 2014.
Hu W, et al. PNAS, Jul 21, 2014.
Genome editing cuts out HIV![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Grens K. The Scientist, Jul 21, 2014.
Grens K. The Scientist, Jul 21, 2014.
Gene researchers work to engineer HIV-resistant cells
Hampton T. JAMA, Jul 9, 2014.
Hampton T. JAMA, Jul 9, 2014.
Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Tebas P, et al. N Engl J Med. 2014 Mar 6;370(10):901-10.
Tebas P, et al. N Engl J Med. 2014 Mar 6;370(10):901-10.
Promising results from HIV gene editing therapy,
PHG Foundation, Mar 10
Testing for risk and protective trends in genetic analyses of HIV acquisition.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Mccarthy JM, et al. Biostatistics. 2014 Sep 29
Mccarthy JM, et al. Biostatistics. 2014 Sep 29
Biomarkers of HIV-associated Cancer.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Flepisi BT, et al. Biomark Cancer. 2014 Jul 3;6:11-20. doi
Flepisi BT, et al. Biomark Cancer. 2014 Jul 3;6:11-20. doi
HIV/AIDS Genomics: Advances in Therapy & Tests - July 31, 2014
RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Hu W, et al. PNAS, Jul 21, 2014.
Hu W, et al. PNAS, Jul 21, 2014.
Genome editing cuts out HIV![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Grens K. The Scientist, Jul 21, 2014.
Grens K. The Scientist, Jul 21, 2014.
Gene researchers work to engineer HIV-resistant cells
Hampton T. JAMA, Jul 9, 2014.
Hampton T. JAMA, Jul 9, 2014.
Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Tebas P, et al. N Engl J Med. 2014 Mar 6;370(10):901-10.
Tebas P, et al. N Engl J Med. 2014 Mar 6;370(10):901-10.
Promising results from HIV gene editing therapy,
PHG Foundation, Mar 10
Check out guidelines on genomic tests associated with HIV/AIDS treatment, from the CDC evidence-based table
HLA-B*5701/abacavir | |
CCR5-tropic HIV-1 /maraviroc |
Diagnostic accuracy of HLA-B*57:01 screening for the prediction of abacavir hypersensitivity and clinical utility of the test: a meta-analytic review![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Cargnin S, et al. Pharmacogenomics. 2014;15(7):963-76.
Cargnin S, et al. Pharmacogenomics. 2014;15(7):963-76.
Did you know? 1799 genes have been reported in relation to HIV risk & outcomes including 33 genomewide association studies. To find out more, visit the HuGE Navigator![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
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