recurrent hydatidiform mole
Recurrent hydatidiform mole occurs when women have at least two abnormal pregnancies described as hydatidiform moles. A hydatidiform mole occurs early in pregnancy when an embryo does not fully develop and the placenta develops abnormally. The placenta is a solid structure inthe uterus that normally provides nutrients to a growing fetus. If a hydatidiform mole occurs once, it is known a sporadic hydatidiform mole; if it happens again, the condition is known as recurrent hydatidiform mole.
A hydatidiform mole often causes vaginal bleeding in the first trimester of the pregnancy. In an ultrasound examination, the abnormal placenta appears as numerous small sacs, often described as resembling a bunch of grapes. In some cases, the ultrasound shows no fetus, umbilical cord, or amniotic sac (a fluid-filled sac that normally surrounds the fetus).
Hydatidiform moles are not naturally discharged from the body and must be surgically removed, typically by the end of the first trimester. After removal, there is up to a 20 percent risk that any tissue left behind (persistent mole) will continue to grow and become a cancerous tumor called an invasive mole. The invasive mole can transform into a different form of cancer called gestational choriocarcinoma that can spread (metastasize) to other tissues such as the liver, lungs, or brain.
Tumors and Pregnancy Update
MedlinePlus sent this bulletin at 04/18/2016 01:10 PM EDTNew on the MedlinePlus Tumors and Pregnancy page:
04/13/2016 02:39 PM EDT
Source: National Library of Medicine -
MEDICAL ENCYCLOPEDIA
National Institutes of Health
Tumors during pregnancy are rare, but they can happen. Tumors can be either benign or malignant. Benign tumors aren't cancer. Malignant ones are. The most common cancers in pregnancy are breast cancer, cervical cancer, lymphoma, and melanoma. Cancer itself rarely harms the baby, and some cancer treatments are safe during pregnancy. You and your health care provider will work together to find the best treatment. Your options will depend on how far along the pregnancy is, as well as the type, size, and stage of your cancer.
Another type of tumor that women can get is called a gestational trophoblastic disease (GTD). It happens when a fertilized egg doesn't become a fetus. GTD is not always easy to find. It is usually benign, but some types can be malignant. The most common type of GTD is a molar pregnancy. In its early stages, it may look like a normal pregnancy. You should see your health care provider if you have vaginal bleeding (not menstrual bleeding).
Treatment depends on the type of tumor, whether it has spread to other places, and your overall health.
- hCG Test (Pregnancy Test) (American Association for Clinical Chemistry)
- How Is Gestational Trophoblastic Disease Diagnosed? (American Cancer Society)
- Stages of Gestational Trophoblastic Tumors and Neoplasia (National Cancer Institute)Available in Spanish
- Gestational Trophoblastic Disease Treatment (National Cancer Institute)
- Treatment of Breast Cancer during Pregnancy (American Cancer Society)
- Treatment Options for Hodgkin Lymphoma during Pregnancy (National Cancer Institute)
- Diethylstilbestrol (DES) and Cancer (National Cancer Institute)Available in Spanish
- Do We Know What Causes Gestational Trophoblastic Disease? (American Cancer Society)
- Other Considerations for Pregnancy and Breast Cancer (National Cancer Institute)
- Detecting and Treating Thyroid Nodules and Cancer Before, During, and After Pregnancy (Hormone Health Network) - PDF
- Molar Pregnancy (Mayo Foundation for Medical Education and Research)
- Pheochromocytoma during Pregnancy (National Cancer Institute)Available in Spanish
- Genetics Home Reference: recurrent hydatidiform mole (National Library of Medicine)
- ClinicalTrials.gov: Gestational Trophoblastic Disease (National Institutes of Health)
- ClinicalTrials.gov: Hydatidiform Mole (National Institutes of Health)
- ClinicalTrials.gov: Pregnancy Complications, Neoplastic (National Institutes of Health)
- ClinicalTrials.gov: Cancer and Pregnancy (National Institutes of Health)
- American Cancer Society
- Find a Cancer Doctor (American Society of Clinical Oncology)
- National Cancer Institute Available in Spanish
- Choriocarcinoma Available in Spanish
- Gestational trophoblastic disease Available in Spanish
- Hydatidiform mole Available in Spanish
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