Crizotinib - National Cancer Institute

Crizotinib - National Cancer Institute

Crizotinib

• 
• 
• 
• 
• 
• 
• 

listen (krih-ZOH-tih-nib)

This page contains brief information about crizotinib and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.

US Brand Name(s)

Xalkori

FDA Approved

Yes

FDA Approval for Crizotinib (2016)

FDA Approval for Crizotinib (2013)

Use in Cancer

Crizotinib is approved to treat:

• Non-small cell lung cancer that has metastasized (spread to other parts of the body). It is used in patients whose cancer has a certain type of chromosomemutation that affects the anaplastic lymphoma kinase (ALK) gene or the ROS1 gene.

Crizotinib is also being studied in the treatment of other types of cancer.

More About Crizotinib

Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.

MedlinePlus Information on Crizotinib - A lay language summary of important information about this drug that may include the following:

• warnings about this drug,
• what this drug is used for and how it is used,
• what you should tell your doctor before using this drug,
• what you should know about this drug before using it,
• other drugs that may interact with this drug, and
• possible side effects.

Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.

Crizotinib Approval Expanded for Advanced Lung Cancer - Information from NCI about this drug.

Targeted Cancer Therapies - Information about the use of this drug to treat cancer.

Research Results

Clinical Trial Results: Crizotinib Improves Progression-Free Survival in Some Patients With Advanced Lung Cancer - Important clinical trial results for this drug, background information, and how the trial was done.

Lung Cancer Precision Medicine Trials: Adapting to Progress - Information from NCI about this drug.

Clinical Trials Accepting Patients

Find Clinical Trials for Crizotinib - Check for trials from NCI's list of cancer clinical trials now accepting patients.

Important: The drug information on this page is meant to be educational. It is not a substitute for medical advice. The information may not cover all possible uses, actions, interactions, or side effects of this drug, or precautions to be taken while using it. Please see your health care professional for more information about your specific medical condition and the use of this drug.

• Posted: October 11, 2011
• Updated: March 24, 2016