Genomics|Features|Cancer Genomics
Cancer Genomics
The Cancer Genome Atlas: Accomplishments and Future - April 3, 2015
The Cancer Genome Atlas (TCGA): an immeasurable source of knowledge![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Tomczak K, et al. Contemp Oncol (Pozn). 2015; 19(1A): A68-A77.
Tomczak K, et al. Contemp Oncol (Pozn). 2015; 19(1A): A68-A77.
The Cancer Genome Atlas' 4th Annual Scientific Symposium![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
May 11-12 ~ Bethesda, MD
May 11-12 ~ Bethesda, MD
The Cancer Genome Atlas (TCGA) Data Portal ![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Portal provides a platform for researchers to search, download, and analyze data sets generated by TCGA
Portal provides a platform for researchers to search, download, and analyze data sets generated by TCGA
Cancer Genomics Hub: A resource of the National Cancer Institute,
from the USC Genome Browser
Molecular classification of gastric adenocarcinoma: translating new insights from The Cancer Genome Atlas Research Network.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Sunakawa Y et al. Curr Treat Options Oncol 2015 Apr (4) 331
Sunakawa Y et al. Curr Treat Options Oncol 2015 Apr (4) 331
TCGA data and patient-derived orthotopic xenografts highlight pancreatic cancer-associated angiogenesis.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Gore J et al. Oncotarget 2015 Feb 25.
Gore J et al. Oncotarget 2015 Feb 25.
Radiogenomics of clear cell renal cell carcinoma: preliminary findings of The Cancer Genome Atlas-Renal Cell Carcinoma (TCGA-RCC) Imaging Research Group.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Shinagare AB et al. Abdom Imaging 2015 Mar 10.
Shinagare AB et al. Abdom Imaging 2015 Mar 10.
Proteomics of colorectal cancer in a genomic context: First large-scale mass spectrometry-based analysis from the Cancer Genome Atlas.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Jimenez CR et al. Clin. Chem. 2015 Feb 26.
Jimenez CR et al. Clin. Chem. 2015 Feb 26.
End of cancer-genome project prompts rethink![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Geneticists debate whether focus should shift from sequencing genomes to analysing function. Heidi Ledford, Nature News and Comments, January 2015
Geneticists debate whether focus should shift from sequencing genomes to analysing function. Heidi Ledford, Nature News and Comments, January 2015
Cancer Genomics: Insights into Driver Mutations - March 10, 2015
Seek and destroy: Relating cancer drivers to therapies![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
E. Martinez-Ledesma et al. Cell, March 9, 2015
E. Martinez-Ledesma et al. Cell, March 9, 2015
In silico prescription of anticancer drugs to cohorts of 28 tumor types reveals targeting opportunities![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
C Rubio-Perez et al. Cancer Cell, March 9, 2015
C Rubio-Perez et al. Cancer Cell, March 9, 2015
MADGiC: a model-based approach for identifying driver genes in cancer.
[PDF 373.56 KB]
Keegan D. Korthauer et al. Bioinformatics, January 2015
Keegan D. Korthauer et al. Bioinformatics, January 2015
Identifying driver mutations in sequenced cancer genomes: computational approaches to enable precision medicine.
Benjamin J Raphael et al. Genome Medicine 2014
Benjamin J Raphael et al. Genome Medicine 2014
Novel recurrently mutated genes in African American colon cancers.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Guda K et al. Proc Natl Acad Sci U S A. 2015 Jan 12
Guda K et al. Proc Natl Acad Sci U S A. 2015 Jan 12
Sparse expression bases in cancer reveal tumor drivers.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Logsdon BA, et al. Nucleic Acids Res. 2015 Jan 12
Logsdon BA, et al. Nucleic Acids Res. 2015 Jan 12
Patient-specific driver gene prediction and risk assessment through integrated network analysis of cancer omics profiles.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Bertrand D, et al. Nucleic Acids Res. 2015 Jan 8
Bertrand D, et al. Nucleic Acids Res. 2015 Jan 8
Identification of constrained cancer driver genes based on mutation timing.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Sakoparnig T, et al. PLoS Comput Biol. 2015 Jan 8;11(1):e1004027
Sakoparnig T, et al. PLoS Comput Biol. 2015 Jan 8;11(1):e1004027
CaMoDi: a new method for cancer module discovery.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Manolakos A, et al. BMC Genomics. 2014 Dec 12;15 Suppl 10:S8.
Manolakos A, et al. BMC Genomics. 2014 Dec 12;15 Suppl 10:S8.
VHL, the story of a tumour suppressor gene.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Gossage L, et al. Nat Rev Cancer. 2014 Dec 23;15(1):55-64
Gossage L, et al. Nat Rev Cancer. 2014 Dec 23;15(1):55-64
Targeting the MET pathway for potential treatment of NSCLC.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Li A, et al. Expert Opin Ther Targets. 2014 Dec 23:1-12
Li A, et al. Expert Opin Ther Targets. 2014 Dec 23:1-12
Deciphering oncogenic drivers: from single genes to integrated pathways.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Chen J, et al. Brief Bioinform. 2014 Nov 5.
Chen J, et al. Brief Bioinform. 2014 Nov 5.
Driver and passenger mutations in cancer.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Pon JR, et al. Annu Rev Pathol. 2014 Oct 17
Pon JR, et al. Annu Rev Pathol. 2014 Oct 17
Cancer Genomics: Impact of Recent Insights - October 30, 2014
Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin.
Katherine A. Hoadley et al. Cell, August 2014
Katherine A. Hoadley et al. Cell, August 2014
Genome study overhauls cancer categories, shifts from tissues to molecular subtypes,
by Kevin Mayer, Genetics Bioengineering News, Aug 8
It's time for us to think about cancer differently,
by Paula Mejia, Newsweek, Aug 8
NIH information: What is cancer genomics and the genetic basis of cancer?![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
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