Fluorouracil (Topical) - National Cancer Institute

Fluorouracil (Topical) - National Cancer Institute









Fluorouracil for Skin Cancer and Other Conditions

We've added a new drug summary for topical fluorouracil, which is used to treat superficial basal cell carcinoma and actinic keratosis.

Fluorouracil (Topical)

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This page contains brief information about topical fluorouracil and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.

US Brand Name(s)

Carac
Tolak
Efudex
Fluoroplex

FDA Approved

Yes

Use in Cancer

Topical fluorouracil is approved to treat:

• Actinic keratosis. This use is approved for the Carac, Efudex, Fluoroplex, and Tolak brands of topical fluorouracil.
• Basal cell carcinoma that is superficial and cannot be removed by surgery. This use is approved for the Efudex brand of topical fluorouracil.

Fluorouracil is also called 5-FU. Fluorouracil is also being studied in the treatment of other conditions and types of cancer.

Fluorouracil is also available in an injection form. For more information, see the Drug Information Summary for Fluorouracil Injection.

More About Fluorouracil (Topical)

Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.

MedlinePlus Information on Topical Fluorouracil - A lay language summary of important information about this drug that may include the following:

• warnings about this drug,
• what this drug is used for and how it is used,
• what you should tell your doctor before using this drug,
• what you should know about this drug before using it,
• other drugs that may interact with this drug, and
• possible side effects.

Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.

Clinical Trials Accepting Patients

Find Clinical Trials for Topical Fluorouracil - Check for trials from NCI's list of cancer clinical trials now accepting patients.

Important: The drug information on this page is meant to be educational. It is not a substitute for medical advice. The information may not cover all possible uses, actions, interactions, or side effects of this drug, or precautions to be taken while using it. Please see your health care professional for more information about your specific medical condition and the use of this drug.