LO ÚLTIMO EN DEGENERACIÓN MACULAR RELACIONADA CON LA EDAD ► Genomics|Features|Age-Related Macular Degeneration [idioma inglés únicamente]

Genomics|Features|Age-Related Macular Degeneration

Age-Related Macular Degeneration

Macular Degeneration: Smoking, Genomics and Public Health - March 30, 2015

CDC Info

• The new smoking story: Going blind
• CDC tips from former smokers
• Common eye diseases include age-related macular degeneration

CDC Feature: The new smoking story: Going blind

CDC tips from former smokers
Marlene developed an advanced eye disease called age-related macular degeneration

Risk factors for macular degeneration
Include smoking, family history and genetics, from the Mayo Clinic

Age-related macular degeneration: insights into inflammatory genes.
Cascella R et al. J Ophthalmol 2014 582842

Nature and nurture- genes and environment- predict onset and progression of macular degeneration.
Sobrin L et al. Prog Retin Eye Res 2014 May 1-15

Genetic testing for age-related macular degeneration: Not indicated now.
Stone EM et al. JAMA Ophthalmol 2015 Mar 19.

Rare genetic variants in the CFI gene are associated with advanced age-related macular degeneration and commonly result in reduced serum factor I levels.
Kavanagh D et al. Hum. Mol. Genet. 2015 Mar 18.

Lens status influences the association between CFH polymorphisms and age-related macular degeneration: Findings from two population-based studies in Singapore.
Wong CW et al. PLoS ONE 2015 (3) e0119570

Association of smoking and CFH and ARMS2 risk variants with younger age at onset of neovascular age-related macular degeneration.
Lechanteur YT et al. JAMA Ophthalmol 2015 Feb 19.

Risk prediction for progression of macular degeneration: 10 common and rare genetic variants, demographic, environmental, and macular covariates.
Seddon JM et al. Invest. Ophthalmol. Vis. Sci. 2015 Feb 5.

Pharmacogenomics of response to anti-VEGF therapy in exudative age-related macular degeneration.
Dedania VS et al. Retina (Philadelphia, Pa.) 2015 Mar (3) 381-91

Genetic testing in persons with age-related macular degeneration and the use of the AREDS supplements: to test or not to test?
Chew EY et al. Ophthalmology 2015 Jan (1) 212-5

Does genetic variation influence response to treatment with vascular endothelial growth factor inhibitors in neovascular age-related macular degeneration?
Chakravarthy U et al. Ophthalmic Epidemiol 2014 Dec (6) 345-6

The role of epigenetics in age-related macular degeneration.
Gemenetzi M et al. Eye (Lond) 2014 Dec (12) 1407-17

Genome-wide association studies: getting to pathogenesis, the role of inflammation/complement in age-related macular degeneration.
Cooke BJ et al. Cold Spring Harb Perspect Med 2014 Dec (12) a017186

Genetic determinants of age-related macular degeneration in diverse populations from the PAGE study.
Restrepo NA et al. Invest. Ophthalmol. Vis. Sci. 2014 Oct (10) 6839-50

Direct-to-consumer personal genome testing for age-related macular degeneration.
Buitendijk GH et al. Invest. Ophthalmol. Vis. Sci. 2014 Oct (10) 6167-74

Age-Related Macular Degeneration: Role of Genetics - November 14, 2013

CDC information: Common eye diseases include age-related macular degeneration

Genetics of age-related macular degeneration: from the NIH Genetics Home Reference

Prediction of age-related macular degeneration in the general population: The three continent AMD consortium.
Buitendijk GH et al. Ophtalmology, Oct 2013

Did you know? 270 genes have been reported with risk and outcome of macular degeneration? The most cited are CFH, ARMS2 and HTRA1. To find out more, visit the HuGE Navigator

Find out which genetic conditions and tests are available for age-related macular degeneration from the NIH Genetic Testing Registry