Meningococcal Disease
Meningococcal Disease, Vaccines and Genomics - April 21, 2015
CDC and Related Info
- Meningococcal disease
- Preteens, teens need Meningococcal vaccine
- Genes reported in relation to risk of meningococcal meningitis, including genomewide association studies via theHuGE Navigator
CDC information:Meningococcal disease
Find out what genes have been reported in relation to risk of meningococcal meningitis,
from the HuGE Navigator
A complement C5 gene mutation, c.754G>A:p.A252T, is common in the Western Cape, South Africa and found to be homozygous in seven percent of Black African meningococcal disease cases.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Owen EP et al. Mol. Immunol. 2015 Mar (1) 170-6
Owen EP et al. Mol. Immunol. 2015 Mar (1) 170-6
Genetic susceptibility to meningococcal infection.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Dale AP et al. Expert Rev Anti Infect Ther 2013 Feb (2) 187-99
Dale AP et al. Expert Rev Anti Infect Ther 2013 Feb (2) 187-99
Host genetics and outcome in meningococcal disease: a systematic review and meta-analysis.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Brouwer MC et al. Lancet Infect Dis 2010 Apr (4) 262-74
Brouwer MC et al. Lancet Infect Dis 2010 Apr (4) 262-74
Competition between antagonistic complement factors for a single protein on N. meningitidis rules disease susceptibility.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Caesar JJ et al. Elife 2014
Caesar JJ et al. Elife 2014
A gene-by-gene population genomics platform: de novo assembly, annotation and genealogical analysis of 108 representative Neisseria meningitidis genomes.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Bratcher HB et al. BMC Genomics 2014 1138
Bratcher HB et al. BMC Genomics 2014 1138
Genetic diversity and levels of expression of factor H binding protein among carriage isolates of Neisseria meningitidis.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Lemée L et al. PLoS ONE 2014 (9) e107240
Lemée L et al. PLoS ONE 2014 (9) e107240
nspA gene as a specific genetic marker for detection of Neisseria meningitidis causing bacterial meningitis.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Bhatt N et al. Indian J. Biochem. Biophys. 2014 Jun (3) 211-4
Bhatt N et al. Indian J. Biochem. Biophys. 2014 Jun (3) 211-4
Prognostic markers of pediatric meningococcal sepsis.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Briassoulis G et al. Expert Rev Anti Infect Ther 2014 Sep (9) 1017-20
Briassoulis G et al. Expert Rev Anti Infect Ther 2014 Sep (9) 1017-20
Draft genome sequence of C:P1.5-1,10-8:F3-6:ST-11 meningococcal clinical isolate associated with a cluster on a cruise ship.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Neri A et al. Genome Announc 2014 (6)
Neri A et al. Genome Announc 2014 (6)
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