Brain Cancer
Brain Cancer: Public Health and Genomic Insights - July 17, 2015
Glioma![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Weller M , et al. Nature Reviews Disease Primers, July 2015
Weller M , et al. Nature Reviews Disease Primers, July 2015
Genomic underpinnings of brain tumors expanded,
National Cancer Institute, June 10
NCI information: Genetic susceptibility and brain tumors![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Risk factors for brain and spinal cord tumors include genetics and family history,
from the American Cancer Society
Check out genes reported with risk and outcomes of brain cancers,
from the HuGE Navigator
Epidemiology and diagnosis of brain tumors.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Butowski NA et al. Continuum (Minneap Minn) 2015 Apr (2 Neuro-oncology) 301-13
Butowski NA et al. Continuum (Minneap Minn) 2015 Apr (2 Neuro-oncology) 301-13
Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
N. Engl. J. Med. 2015 Jun 10.
N. Engl. J. Med. 2015 Jun 10.
Beyond the World Health Organization grading of infiltrating gliomas: advances in the molecular genetics of glioma classification.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Vigneswaran K et al. Ann Transl Med 2015 May (7) 95
Vigneswaran K et al. Ann Transl Med 2015 May (7) 95
Molecular and genomic alterations in glioblastoma multiforme.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Crespo I et al. Am. J. Pathol. 2015 May 11.
Crespo I et al. Am. J. Pathol. 2015 May 11.
The emerging molecular foundations of pediatric brain tumors.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Huse JT et al. J. Child Neurol. 2015 Apr 14.
Huse JT et al. J. Child Neurol. 2015 Apr 14.
Brain tumor mutations detected in cerebral spinal fluid.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Pan W et al. Clin. Chem. 2015 Mar (3) 514-22
Pan W et al. Clin. Chem. 2015 Mar (3) 514-22
Germline mutations in shelterin complex genes are associated with familial glioma.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Bainbridge MN et al. J. Natl. Cancer Inst. 2015 Jan (1) 384
Bainbridge MN et al. J. Natl. Cancer Inst. 2015 Jan (1) 384
Epidemiology of gliomas.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Ostrom QT et al. Cancer Treat. Res. 2015 1-14
Ostrom QT et al. Cancer Treat. Res. 2015 1-14
Risk score based on microRNA expression signature is independent prognostic classifier of glioblastoma patients.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Sana J et al. Carcinogenesis 2014 Dec (12) 2756-62
Sana J et al. Carcinogenesis 2014 Dec (12) 2756-62
Molecular characterizations of glioblastoma, targeted therapy, and clinical results to date.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Bastien JI et al. Cancer 2015 Feb 15. (4) 502-16
Bastien JI et al. Cancer 2015 Feb 15. (4) 502-16
Central nervous system germ cell tumors: an update.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Dufour C et al. Curr Opin Oncol 2014 Nov (6) 622-6
Dufour C et al. Curr Opin Oncol 2014 Nov (6) 622-6
Unique genetic and epigenetic mechanisms driving paediatric diffuse high-grade glioma.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Jones C et al. Nat. Rev. Cancer 2014 Oct (10)
Jones C et al. Nat. Rev. Cancer 2014 Oct (10)
Whole genome sequencing of glioblastoma multiforme identifies multiple structural variations involved in EGFR activation.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Furgason JM et al. Mutagenesis 2014 Sep (5) 341-50
Furgason JM et al. Mutagenesis 2014 Sep (5) 341-50
Genomic landscape of glioblastoma and the potential clinical utility.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Wang CJ et al. CNS Oncol 2014 May (3) 169-72
Wang CJ et al. CNS Oncol 2014 May (3) 169-72
Molecular and genetic pathways in gliomas: the future of personalized therapeutics.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Grant R et al. CNS Oncol 2014 Mar (2) 123-36
Grant R et al. CNS Oncol 2014 Mar (2) 123-36
The molecular landscape of pediatric brain tumors in the next-generation sequencing era.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Firme MR et al. Curr Neurol Neurosci Rep 2014 Sep (9) 474
Firme MR et al. Curr Neurol Neurosci Rep 2014 Sep (9) 474
Advances in genetic and epigenetic analyses of gliomas: a neuropathological perspective.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Tsankova NM et al. J. Neurooncol. 2014 Sep (3) 481-90
Tsankova NM et al. J. Neurooncol. 2014 Sep (3) 481-90
Gene therapy shows early promise against deadly brain cancer,
by Alan Mozes, HealthDay, Mayo Clinic, May 31
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