Systemic Lupus Erythematosus
Systemic Lupus Erythematosus: Public Health and Genomic Insights - July 20, 2015
CDC information: SLE is an autoimmune disease in which the immune system makes antibodies to cells in the body leading to widespread inflammation and tissue damage.
CDC information: Although there is a strong familial aggregation in SLE, the disease is relatively uncommon and most cases are sporadic
Find out which genetic disorders and tests are associated with systemic lupus erythematosus,
from the NIH Genetic Testing Registry
from the NIH Genetic Testing RegistryFind out which genes have been reported in relation to SLE, from the HuGE Navigator
from the HuGE NavigatorGene/environment interactions in the pathogenesis of autoimmunity: New insights on the role of toll-like receptors.
Gianchecchi E et al. Autoimmun Rev 2015 Jul 13.
Gianchecchi E et al. Autoimmun Rev 2015 Jul 13.
Genetics and novel aspects of therapies in systemic lupus erythematosus.
Relle M et al. Autoimmun Rev 2015 Jul 9.
Relle M et al. Autoimmun Rev 2015 Jul 9.
Familial aggregation of systemic lupus erythematosus and coaggregation of autoimmune diseases in affected families
Kuo CF et al. JAMA Internal Medicine, July 20, 2015
Kuo CF et al. JAMA Internal Medicine, July 20, 2015
Inflammasome polymorphisms in juvenile systemic lupus erythematosus.
Pontillo A et al. Autoimmunity 2015 Jul 16. 1-4
Pontillo A et al. Autoimmunity 2015 Jul 16. 1-4
Genetic variants of IκB Kinase ß (IKBKB) and polymerase ß (POLB) were not associated with systemic lupus erythematosus risk in a Chinese Han population.
Li Y et al. PLoS ONE 2015 (7) e0132556
Li Y et al. PLoS ONE 2015 (7) e0132556
The real culprit in systemic lupus erythematosus: abnormal epigenetic regulation.
Wu H et al. Int J Mol Sci 2015 (5) 11013-33
Wu H et al. Int J Mol Sci 2015 (5) 11013-33
Genetic architectures of seropositive and seronegative rheumatic diseases.
Kirino Y et al. Nat Rev Rheumatol 2015 Jul (7) 401-14
Kirino Y et al. Nat Rev Rheumatol 2015 Jul (7) 401-14
Genome-wide search followed by replication reveals genetic interaction of CD80 and ALOX5AP associated with systemic lupus erythematosus in Asian populations.
Zhang Y et al. Ann. Rheum. Dis. 2015 Apr 10.
Zhang Y et al. Ann. Rheum. Dis. 2015 Apr 10.
Genome-wide association study identifies new susceptibility loci for cutaneous lupus erythematosus.
Kunz M et al. Exp. Dermatol. 2015 Jul (7) 510-5
Kunz M et al. Exp. Dermatol. 2015 Jul (7) 510-5
Genetics and pathogenesis of systemic lupus erythematosus and lupus nephritis.
Mohan C et al. Nat Rev Nephrol 2015 Jun (6) 329-341
Mohan C et al. Nat Rev Nephrol 2015 Jun (6) 329-341
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