Alzheimer's Disease
Early Onset Alzheimer's Disease: Genetic Insights - July 23, 2015
Younger adults with Alzheimer's are key to drug search,
National Public Radio, Jul 23
Genetic testing and counseling in the diagnosis and management of young-onset dementias.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Goldman JS et al. Psychiatr. Clin. North Am. 2015 Jun (2) 295-308
Goldman JS et al. Psychiatr. Clin. North Am. 2015 Jun (2) 295-308
Autosomal dominant Alzheimer disease: A unique resource to study CSF biomarker changes in preclinical AD.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Schindler SE et al. Front Neurol 2015 142
Schindler SE et al. Front Neurol 2015 142
Brain imaging and blood biomarker abnormalities in children with autosomal dominant Alzheimer disease: A cross-sectional study.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Quiroz YT et al. JAMA Neurol 2015 Jun 29.
Quiroz YT et al. JAMA Neurol 2015 Jun 29.
R47H variant of TREM2 associated with Alzheimer disease in a large late-onset family: Clinical, genetic, and neuropathological study.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Korvatska O et al. JAMA Neurol 2015 Jun 15.
Korvatska O et al. JAMA Neurol 2015 Jun 15.
Diagnostic value of subjective memory complaints assessed with a single item in dominantly inherited Alzheimer's disease: Results of the DIAN study.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Laske C et al. Biomed Res Int 2015 828120
Laske C et al. Biomed Res Int 2015 828120
Early behavioural changes in familial Alzheimer's disease in the Dominantly Inherited Alzheimer Network.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Ringman JM et al. Brain 2015 Apr (Pt 4) 1036-45
Ringman JM et al. Brain 2015 Apr (Pt 4) 1036-45
Associations between biomarkers and age in the presenilin 1 E280A autosomal dominant Alzheimer disease kindred: a cross-sectional study.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Fleisher AS et al. JAMA Neurol 2015 Mar (3) 316-24
Fleisher AS et al. JAMA Neurol 2015 Mar (3) 316-24
Alzheimer's Disease: Genomic Insights - June 18, 2015
Associations between potentially modifiable risk factors and Alzheimer disease: A Mendelian randomization study.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Østergaard Søren D et al. PLoS Med. 2015 Jun (6) e1001841
Østergaard Søren D et al. PLoS Med. 2015 Jun (6) e1001841
Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Mukherjee S et al. Alzheimers Dement 2015 Jun 12.
Mukherjee S et al. Alzheimers Dement 2015 Jun 12.
Prevalence of Amyloid PET positivity in dementia syndromes: A meta-analysis![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Ossenkoppele R et al, JAMA May 19, 2015
Ossenkoppele R et al, JAMA May 19, 2015
Prevalence of cerebral amyloid pathology in persons without dementia: A meta-analysis![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Jansen WJ et al, JAMA, May 19, 2015
Jansen WJ et al, JAMA, May 19, 2015
Defining amyloid pathology in persons with and without dementia syndromes - making the right diagnosis ![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Rosenberg RN , JAMA May 19, 2015
Rosenberg RN , JAMA May 19, 2015
National plan to address Alzheimer's disease:
2014 update
Additional mechanisms conferring genetic susceptibility to Alzheimer's disease.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Calero M et al. Front Cell Neurosci 2015 138
Calero M et al. Front Cell Neurosci 2015 138
Predicting Alzheimer's disease using combined imaging-whole genome SNP data.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Kong D et al. J. Alzheimers Dis. 2015 Apr 13.
Kong D et al. J. Alzheimers Dis. 2015 Apr 13.
Polygenic overlap between C-reactive protein, plasma lipids and Alzheimer's disease.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Desikan RS et al. Circulation 2015 Apr 10.
Desikan RS et al. Circulation 2015 Apr 10.
PLD3 gene variants and Alzheimer's disease.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Hooli BV et al. Nature 2015 Apr 2. (7545) E7-8
Hooli BV et al. Nature 2015 Apr 2. (7545) E7-8
PLD3 in non-familial Alzheimer's disease.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Heilmann S et al. Nature 2015 Apr 2. (7545) E3-5
Heilmann S et al. Nature 2015 Apr 2. (7545) E3-5
PLD3 variants in population studies.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
van der Lee SJ et al. Nature 2015 Apr 2. (7545) E2-3
van der Lee SJ et al. Nature 2015 Apr 2. (7545) E2-3
Genetic variability in SQSTM1 and risk of early-onset Alzheimer dementia: a European early-onset dementia consortium study.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Cuyvers E et al. Neurobiol. Aging 2015 May (5) 2005.e15-22
Cuyvers E et al. Neurobiol. Aging 2015 May (5) 2005.e15-22
A novel Alzheimer disease locus located near the gene encoding tau protein.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Jun G et al. Mol. Psychiatry 2015 Mar 17.
Jun G et al. Mol. Psychiatry 2015 Mar 17.
The biomarker and therapeutic potential of miRNA in Alzheimer's disease.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Bekris LM et al. Neurodegener Dis Manag 2015 Feb (1) 61-74
Bekris LM et al. Neurodegener Dis Manag 2015 Feb (1) 61-74
Alzheimer's Disease: Genomic Insights - March 3, 2015
Personalized Medicine for Effective Alzheimer Disease Treatment.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Kosik Kenneth S et al. JAMA Neurol 2015 Mar 2.
Kosik Kenneth S et al. JAMA Neurol 2015 Mar 2.
Association of Alzheimer's disease GWAS loci with MRI markers of brain aging.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Chauhan Ganesh et al. Neurobiol. Aging 2015 Jan 6.
Chauhan Ganesh et al. Neurobiol. Aging 2015 Jan 6.
Examination of candidate exonic variants for association to Alzheimer disease in the Amish.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
D'Aoust Laura N et al. PLoS ONE 2015 (2) e0118043
D'Aoust Laura N et al. PLoS ONE 2015 (2) e0118043
The influence of genetic variants in SORL1 gene on the manifestation of Alzheimer's disease.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Louwersheimer Eva et al. Neurobiol. Aging 2014 Dec 11.
Louwersheimer Eva et al. Neurobiol. Aging 2014 Dec 11.
Identifying genetic interactions associated with late-onset Alzheimer's disease.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Floudas Charalampos S et al. BioData Min 2014 (1) 35
Floudas Charalampos S et al. BioData Min 2014 (1) 35
Genetic determinants of survival in patients with Alzheimer's disease.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Wang Xingbin et al. J. Alzheimers Dis. 2015 Feb 3.
Wang Xingbin et al. J. Alzheimers Dis. 2015 Feb 3.
Genome-wide studies of verbal declarative memory in nondemented older people: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Debette Stéphanie et al. Biol. Psychiatry 2014 Nov 25.
Debette Stéphanie et al. Biol. Psychiatry 2014 Nov 25.
Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949).![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Davies G et al. Mol. Psychiatry 2015 Feb 3.
Davies G et al. Mol. Psychiatry 2015 Feb 3.
The effects of two polymorphisms on p21cip1 function and their association with Alzheimer's disease in a population of European descent.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Yates Sharon C et al. PLoS ONE 2015 (1) e0114050
Yates Sharon C et al. PLoS ONE 2015 (1) e0114050
Evaluation of candidate genes related to neuronal apoptosis in late-onset Alzheimer's disease.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Moreno-Grau Sonia et al. J. Alzheimers Dis. 2015 Jan 22.
Moreno-Grau Sonia et al. J. Alzheimers Dis. 2015 Jan 22.
Common genetic variants influence human subcortical brain structures.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Hibar Derrek P et al. Nature 2015 Jan 21.
Hibar Derrek P et al. Nature 2015 Jan 21.
Associations between biomarkers and age in the presenilin 1 E280A autosomal dominant Alzheimer disease kindred: A cross-sectional study.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Fleisher Adam S et al. JAMA Neurol 2015 Jan 12.
Fleisher Adam S et al. JAMA Neurol 2015 Jan 12.
Convergent genetic and expression data implicate immunity in Alzheimer's disease.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
International Genomics of Alzheimer's Disease Consortium (IGAP). Alzheimers Dement 2014 Dec 20.
International Genomics of Alzheimer's Disease Consortium (IGAP). Alzheimers Dement 2014 Dec 20.
Alzheimer's Disease: Recent Genomic Insights - December 4, 2014
A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death.
Monica K Wetzel-Smith et al. Nature Medicine, November 24, 2014
Monica K Wetzel-Smith et al. Nature Medicine, November 24, 2014
Genetics of Alzheimer's disease.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Chouraki V, Seshadri S. Adv Genet. 2014;87:245-94.
Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
O'Bryant SE et al. Alzheimers Dement. 2014 Sep 27. pii: S1552-5260(14)02765-4.
Chouraki V, Seshadri S. Adv Genet. 2014;87:245-94.
Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research.
O'Bryant SE et al. Alzheimers Dement. 2014 Sep 27. pii: S1552-5260(14)02765-4.
Alzheimer's test detects disease decade ahead of onset,
by Megan Scudellari, Bloomberg News, Nov 17
New blood-based Alzheimer's biomarker panel uses exosomal miRNA,
by Madeleine Johnson, GenomeWeb, Nov 21 [by free subscription only]
Alzheimer's Disease Awareness: Genetics and Family Health History - September 25, 2014
CDC information: September is World Alzheimer's Month- Risk factors for Alzheimer's disease include genetics
CDC report: 2013-2018 Road Map- The Healthy Brain Initiative
Alzheimer's disease genetics fact sheet,
from the National Institute on Aging
Did you know? 1621 genes have been reported in relation to risk or outcomes of Alzheimer's disease, including 155 genomewide association studies? ApoE is the most commonly reported gene. To find out more, visit the HuGE Navigator![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Find out what genetic conditions and tests are associated with Alzheimer's disease,
NIH Genetic Testing Registry
Is Alzheimer's disease genetic?
WebMD, July 2014
Alzheimer's genes: Are you at risk?
Several genes have been associated with Alzheimer's disease, but more research is needed, Mayo Clinic
Alzheimer's Disease and Genetics: Recent Insights - August 21, 2014
CDC information: Facts about Alzheimer's disease
CDC report: 2013-2018 Road Map- The Healthy Brain Initiative
Did you know? 1615 genes have beern reported in relation to risk our outcomes of Alzheimer's disease, including 149 genomewide association studies? ApoE is the most commonly reported gene. To find out more, visit the HuGE Navigator![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Find out what genetic conditions and tests are associated with Alzheimer's disease,
NIH Genetic Testing Registry
Recent Insights
Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy.
Chia-Chen Liu et al. Nature Reviews Neurology 9, 106-118 (February 2013)
Chia-Chen Liu et al. Nature Reviews Neurology 9, 106-118 (February 2013)
Is apolipoprotein E required for cognitive function in humans? Implications for Alzheimer drug development![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vOkHr9hY24SDMzkVM2iUOXfIhqzUiqUlvYrAtOFFk0w5uVVJbXYGfx7VBrBflBpn92jbUG7WOCJSMPV2leo-6k7u6JZ0omR8iphwnji-lXPZwAaFf8SAAS=s0-d)
Courtney Lane-Donovan et al. JAMA Neurology, August 11, 2014
Courtney Lane-Donovan et al. JAMA Neurology, August 11, 2014
Delete ApoE gene, set back Alzheimer's, and preserve brain health?
GEN News Highlights, Aug 12
Effects of the absence of apolipoprotein E on lipoproteins, neurocognitive function, and retinal function.
Mak AC et al, JAMA Neurol. 2014 Aug 11.
Mak AC et al, JAMA Neurol. 2014 Aug 11.
Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease.
Katie Lunnon et al. Nature Neuroscience, August 18, 2014
Katie Lunnon et al. Nature Neuroscience, August 18, 2014
Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.
Philip L De Jager et al. Nature Neuroscience, August 18, 2014
Philip L De Jager et al. Nature Neuroscience, August 18, 2014
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